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检索条件"主题词=PARPi resistance"
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The evolving role of DNA damage response in overcoming therapeutic resistance in ovarian cancer
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Cancer Drug resistance 2023年 第2期6卷 345-357页
作者: Sara Bouberhan Liron Bar-Peled Yusuke Matoba Varvara Mazina Lauren Philp Bo R.eda Division of Hematology/Oncology Department of MedicineMassachusetts General HospitalBostonMA 02114USA Department of Medicine Harvard Medical SchoolBostonMA 02115USA Center for Cancer Research Massachusetts General HospitalBostonMA 02114USA Department of Obstetrics and Gynecology Vincent Center for Reproductive BiologyMassachusetts General HospitalBostonMA 02114USA Obstetrics Gynecologyand Reproductive BiologyHarvard Medical SchoolBostonMA 02115 USA Division of Gynecologic Oncology Department of Obstetrics and GynecologyMassachusetts General HospitalBostonMA 02114USA
Epithelial ovarian cancer(EOC)is treated in the first-line setting with combined platinum and taxane chemotherapy,often followed by a maintenance poly(ADP-ribose)polymerase inhibitor(parpi).Responses to first-line tre... 详细信息
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