检索结果-南通市图书馆

Towards an actionable one health approach

贫困所致传染病(英文) 2024年第2期13卷 1-6页

作者： Zhang Xiao-Xi Lederman Zohar Han Le-Fei Schurer Janna M. Xiao Li-Hua Zhang Zhi-Bing Chen Qiu-Lan Pfeiffer Dirk Ward Michael P. Sripa Banchob Gabri?l Sarah Dhama Kuldeep Acharya Krishna Prasad Robertson Lucy J. Deem Sharon L. Aenishaenslin Cécile Dantas-Torres Filipe Otranto Domenico Grace Delia Wang Yang Li Peng Fu Chao Poeta Patrícia Rahman Md. Tanvir Kassegne Kokouvi Zhu Yong-Zhang Yin Kun Liu Jiming Wang Zhao-Jun Guo Xiao-Kui Gong Wen-Feng Schwartl?nder Bernhard Ren Ming-Hui Zhou Xiao-Nong Sydney School of Veterinary Science The University of Sydney Camden Australia Tropical Disease Research Center Department of Tropical Medicine Faculty of Medicine Khon Kaen University Khon Kaen Thailand Laboratory of foodborne parasitic zoonoses Department of translational physiology infectiology and public health Chair Faculty Committee on Internationalisation Faculty of Veterinary Medicine Ghent University Merelbeke Belgium Division of Pathology ICAR-Indian Veterinary Research Institute (IVRI) Bareilly Uttar Pradesh India Department of Livestock Services Animal Quarantine Office-Kathmandu Budhanilkantha Kathmandu Nepal Parasitology Department of Paraclinical Sciences Faculty of Veterinary Medicine Norwegian University of Life Sciences ?s Norway one Government Drive Saint Louis Zoo Institute for Conservation Medicine St. Louis USA Groupe de Recherche en épidémiologie des Zoonoses et Santé Publique (GREZOSP) Faculté de médecine vétérinaire Université de Montréal Saint-Hyacinthe Québec Canada Centre de recherche en santé publique de l Université de Montréal et du CIUSSS du Centre-Sud-de-l’?le-de-Montréal Montréal Québec Canada Department of Immunology Aggeu Magalh?es Institute Oswaldo Cruz Foundation (Fiocruz) Recife Brazil School of Global health Chinese Center for Tropical Diseases Research Shanghai Jiao Tong University School of Medicine Shanghai People’s Republic of China Department of Veterinary Medicine University of Bari Valenzano Italy Department of Pathobiology Faculty of Veterinary Science Bu-Ali Sina University Hamedan Iran Natural Resources Institute University of Greenwich Chatham Maritime UK International Livestock Research Institute Nairobi Kenya Director of Key Laboratory of Animal Antimicrobial Resistance Surveillance Ministry of Agriculture and Rural Affairs Beijing People’s Republic of China Institute of Animal Science Chinese Academy of Agricultural Sciences Beijing People’s Republic of China Key Laboratory of Ecosystem Network O

Background Despite the increasing focus on strengthening one health capacity building on global level, challenges remain in devising and implementing real-world interventions particularly in the Asia-Pacific region. Recognizing these gaps, the one health Action Commission (OHAC) was established as an academic community for one health action with an emphasis on research agenda setting to identify actions for highest impact.Main text This viewpoint describes the agenda of, and motivation for, the recently formed OHAC. Recognizing the urgent need for evidence to support the formulation of necessary action plans, OHAC advocates the adoption of both bottom-up and top-down approaches to identify the current gaps in combating zoonoses, antimicrobial resistance, addressing food safety, and to enhance capacity building for context-sensitive one health implementation.Conclusions By promoting broader engagement and connection of multidisciplinary stakeholders, OHAC envisions a collaborative global platform for the generation of innovative one health knowledge, distilled practical experience and actionable policy advice, guided by strong ethical principles of one health.

关键词： one health Global health one health Action Commission Research agenda

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Avian influenza and gut microbiome in poultry and humans:A“one health”perspective

引用

Fundamental Research 2024年第3期4卷 455-462页

作者： Ling Zhang Erkai Zhou Ce Liu Xiaoyu Tian Baode Xue Kai Zhang Bin Luo Institute of Occupational health and Environmental health School of Public HealthLanzhou UniversityLanzhouGansu 730000China Department of Environmental health Sciences School of Public HealthUniversity at AlbanyState University of New YorkRensselaerNY 12144USA Shanghai Key Laboratory of Meteorology and health Shanghai Meteorological BureauShanghai 200030China Shanghai Typhoon Institute China Meteorological AdministrationShanghai 200030China

A gradual increase in avian influenza outbreaks has been found in recent years.It is highly possible to trigger the next human pandemic due to the characteristics of antigenic drift and antigenic shift in avian influenza virus(AIV).Although great improvements in understanding influenza viruses and the associated diseases have been unraveled,our knowledge of how these viruses impact the gut microbiome of both poultry and humans,as well as the underlying mechanisms,is still improving.The“one health”approach shows better vitality in monitoring and mitigating the risk of avian influenza,which requires a multi-sectoral effort and highlights the interconnection of human health with environmental sustainability and animal health.Therefore,monitoring the gut microbiome may serve as a sentinel for protecting the common health of the environment,animals,and humans.This review summarizes the interactions between AIV infection and the gut microbiome of poultry and humans and their potential mechanisms.With the presented suggestions,we hope to address the current major challenges in the surveillance and prevention of microbiome-related avian influenza with the“one health”approach.

关键词： Avian influenza AIV Poultry Gutmicrobiome one health Poultry-Environment-Human Interface

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A one health approach to fight antimicrobial resistance in Uganda: Implementation experience, results, and lessons learned

引用

Biosafety and health 2024年第2期6卷 125-132页

作者： Reuben Kiggundu J.P.Waswa Niranjan Konduri Hassan Kasuja Marion Murungi Patrick Vudriko Harriet Akello Eric Lugada Cecilia Muiva Esther Were Dinah Tjipura Henry Kajumbula Kate Kikule Emmanuel Nfor Mohan P.Joshi USAID Medicines Technologiesand Pharmaceutical Services ProgramManagement Sciences for HealthKampala 256Uganda USAID Medicines Technologiesand Pharmaceutical Services ProgramManagement Sciences for HealthArlingtonVA 22203USA College of Veterinary Medicine Animal Resources and BiosecurityMakerere UniversityKampala 256Uganda Ministry of health Uganda Kampala 256Uganda USAID Strengthening Supply Chain Systems Activity Management Sciences for HealthKampala 256Uganda USAID Medicines Technologiesand Pharmaceutical Services ProgramManagement Sciences for HealthNairobi 254Kenya Department of Microbiology College of Health SciencesMakerere UniversityKampala 256Uganda

Uganda has been implementing the Global health Security Agenda(GHSA)since 2015 to build its capacity according to World health Organization(WHO)Benchmarks on International health Regulations Capacities.The country remains prone to outbreaks,with more than 2o disease outbreaks reported in the past five years,including Ebola virus disease,Crimean-Congo haemorrhagic fever,Marburg haemorrhagic fever,measles,yel-low fever,coronavirus disease 2019(COVID-19),and cholera.Antimicrobial resistance(AMR)is an ongoing challenge.Uganda scored capacity level 3 on infection prevention and control(IPC)and antimicrobial steward-ship(AMS)in the 2017 Joint External Evaluation(JEE)assessment.Identified gaps were being addressed after a self-assessment in 2021.This paper describes the technical assistance approaches provided to Uganda by the Medicines,Technologies,and Pharmaceutical Services Program,funded by the United States(U.S.)Agency for International Development,and implemented by Management Sciences for health.The program,through a one health approach,supported systematic capacity strengthening based on the JEE's capacity advancement framework for global health security,specifically relating to AMR.The program's interventions impacted 32 WHO benchmark actions(7 for AMR multisectoral coordination,16 for IPC,and 9 for AMS),contributing to Uganda's strengthened GHSA capacity.Leveraging success built on the AMR platform,the program trained 745 health workers in IPC for the Ebola virus and provided support for simulation exercises by eight district IPC teams.The program also worked with the Ministry of health to coordinate IPC for the COVID-19 response in five health regions,covering 45 districts and reaching 5,452 health workers at 858 health facilities.2024 Chinese Medical Association Publishing House.Published by Elsevier BV.

关键词： one health Antimicrobial resistance Antibiotic resistance Jointexternal evaluation Global health security Uganda Africa WHO Benchmarks for International health Regulations Capacities

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

世界动物卫生组织one health总体框架及最新关注方向

引用

动物医学进展 2024年第4期45卷 121-125页

作者：耿庆华廖立珊李修平林茜茜吴江孙洁刘荭沈阳海关技术中心辽宁沈阳110016 深圳市检验检疫科学研究院深圳海关动植物检验检疫技术中心广东深圳518000 济宁海关综合服务技术中心山东济宁272000 兰州海关甘肃兰州730000

近年来,人兽共患病在全球越来越多的地方影响人类和动物的健康。在此背景下,由联合国粮食及农业组织(FAO)、世界卫生组织(WHO)和世界动物卫生组织(WOAH)三方国际组织提出了“one health”的概念。2021年底,FAO、WOAH、WHO和联合国环境... 详细信息

近年来,人兽共患病在全球越来越多的地方影响人类和动物的健康。在此背景下,由联合国粮食及农业组织(FAO)、世界卫生组织(WHO)和世界动物卫生组织(WOAH)三方国际组织提出了“one health”的概念。2021年底,FAO、WOAH、WHO和联合国环境规划署(UNEP)共同成立了one health高级别委员会(one health High Level Expert Panel,OHHLEP),并将“one health”重新定义。论文就“one health”的概念、提出的背景、重要发展进程、总体框架和协调机制以及未来应用展望进行了全面的介绍和阐述,为我国进一步深入了解“one health”理念,实践并更好地应用“one health”方法,从而解决我国人兽共患病、抗生素耐药等对人类、动物和环境危害严重的问题提供思路和参考。

关键词： one health 发展进程总体框架协调机制未来应用

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

one health: navigating plague in Madagascar amidst COVID-19

引用

Infectious Diseases of Poverty 2023年第3期12卷 67-72页

作者： Ritik Agrawal Jogesh Murmu Sweta Pattnaik Srikanta Kanungo Sanghamitra Pati ICMR-Regional Medical Research Centre BhubaneswarOdishaIndia

Background Africa sees the surge of plague cases in recent decades,with hotspots in the Democratic Republic of Congo,Madagascar,and Peru.A rodent-borne scourge,the bacterial infection known as plague is transmitted to humans via the sneaky bites of fleas,caused by Yersinia pestis.Bubonic plague has a case fatality rate of 20.8%with treatment,but in places such as Madagascar the mortality rate can increase to 40–70%without treatment.Main text Tragedy strikes in the Ambohidratrimo district as three lives are claimed by the plague outbreak and three more fight for survival in the hospitals,including one man in critical condition,from the Ambohimiadana,Antsaharasty,and Ampanotokana communes,bringing the total plague victims in the area to a grim to five.Presently,the biggest concern is the potential plague spread among humans during the ongoing COVID-19 pandemic.Effective disease control can be achieved through training and empowering local leaders and healthcare providers in rural areas,implementing strategies to reduce human–rodent interactions,promoting water,sanitation and hygiene practices(WASH)practices,and carrying out robust vector,reservoir and pest control,diversified animal surveillance along with human surveillance should be done to more extensively to fill the lacunae of knowledge regarding the animal to human transmission.The lack of diagnostic laboratories equipped represents a major hurdle in the early detection of plague in rural areas.To effectively combat plague,these tests must be made more widely available.Additionally,raising awareness among the general population through various means such as campaigns,posters and social media about the signs,symptoms,prevention,and infection control during funerals would greatly decrease the number of cases.Furthermore,healthcare professionals should be trained on the latest methods of identifying cases,controlling infections and protecting themselves from the disease.Conclusions Despite being endemic to Madagascar,the outbreak’s pace is unparalleled,and it ma

关键词： Plague Madagascar WASH Surveillance Animal surveillance one health Yersinia pestis Early warning

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Social insights on the implementation of one health in zoonosis prevention and control: a scoping review

引用

Infectious Diseases of Poverty 2022年第3期11卷 1-11页

作者： Junyi He Zhaoyu Guo Pin Yang Chunli Cao Jing Xu Xiaonong Zhou Shizhu Li National Institute of Parasitic Diseases Chinese Center for Disease Control and Prevention(Chinese Center for Tropical Diseases Research)NHC Key Laboratory of Parasite and Vector BiologyWHO Collaborating Centre for Tropical DiseasesNational Center for International Research on Tropical DiseasesShanghai200025China School of Global health Chinese Center for Tropical Diseases ResearchShanghai Jiao Tong University School of MedicineShanghai200025China

Background:The one health (OH) concept has been promoted widely around the globe. OH framework is expected to be applied as an integrated approach to support addressing zoonotic diseases as a significant global health issue and to improve the efficiency and effectiveness of zoonosis prevention and control. This review is intended to overview the social impact of the implementation of OH on zoonosis prevention and control.Methods:A scoping review of studies in the past 10 years was performed to overview the integration feature of OH in zoonosis prevention and control and the social impacts of OH. PubMed and Web of Science were searched for studies published in English between January 2011 and June 2021. The included studies were selected based on predefined criteria.Results:Thirty-two studies were included in this review, and most of them adopted qualitative and semi-qualitative methods. More than 50% of the studies focused on zoonosis prevention and control. Most studies were conducted in low- and middle-income countries in Africa and Asia. Applying OH approach in diseases control integrates policymakers, stakeholders, and academics from various backgrounds. The impact of OH on economic is estimated that it may alleviate the burden of diseases and poverty in the long term, even though more financial support might be needed at the initial stage of OH implementation. OH implementation considers social and ecological factors related to zoonosis transmission and provides comprehensive strategies to assess and address related risks in different communities according to regions and customs.Conclusions:Based on reviewed literature, although there seems to be a lack of guidelines for assessing and visualizing the outcomes of OH implementation, which may limit the large-scale adoption of it, evidence on the contributions of implementing OH concepts on zoonosis prevention and control indicates long-term benefits to society, including a better integration of politics, stakeholders and academics to improve their cooperation,

关键词： one health Zoonotic diseases Social impacts Social perspectives

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Tackling global health security by building an academic community for one health action

引用

Infectious Diseases of Poverty 2023年第4期12卷 93-98页

作者： Xiao-Xi Zhang Xin-Chen Li Qi-Yu Zhang Jing-Shu Liu Le-Fei Han Zohar Lederman Janna M.Schurer Patrícia Poeta Md.Tanvir Rahman Shi-Zhu Li Kokouvi Kassegne Kun Yin Yong-Zhang Zhu Shang Xia Lu He Qin-Qin Hu Le-Shan Xiu Jing-Bo Xue Han-Qing Zhao Xi-Han Wangv Logan Wu Xiao-Kui Guo Zhao-Jun Wang Bernhard Schwartländer Ming-Hui Ren Xiao-Nong Zhou School of Global health Chinese Center for Tropical Diseases ResearchShanghai Jiao Tong University School of MedicineShanghaiPeople’s Republic of China Institute of one health Shanghai Jiao Tong UniversityShanghaiPeople’s Republic of China Medical Ethics and Humanities Unit Hong Kong UniversityHong KongPeople’s Republic of China Center for one health University of Global Health EquityButaroRwanda Microbiology and Antibiotic Resistance Team Department of Veterinary SciencesUniversity of Trás-os-Montes and Alto DouroVila RealPortugal Associate Laboratory for Green Chemistry Chemistry DepartmentUniversity Nova of LisbonLisbonPortugal Veterinary and Animal Research Centre University of Trás-os-Montes and Alto DouroVila RealPortugal Associate Laboratory for Animal and Veterinary Sciences University of Trás-os-Montes and Alto DouroVila RealPortugal Department of Microbiology and Hygiene Bangladesh Agricultural UniversityMymensinghBangladesh National Institute of Parasitic Diseases at Chinese Center for Disease Control and Prevention(Chinese Center for Tropical Diseases Research) NHC Key Laboratory of Parasite and Vector BiologyWHO Collaborating Centre for Tropical DiseasesShanghaiPeople’s Republic of China Walter and Eliza Hall Institute ParkvilleAustralia Department of Medical Biology University of MelbourneMelbourneAustralia German Ministry of Foreign Affairs(Former Assistant Director General and Chef de Cabinet of Dr Tedros at the World health Organization) BerlinGermany School of Public health Peking UniversityBeijingPeople’s Republic of China

Background one health approach is crucial to tackling complex global public health threats at the interface of humans, animals, and the environment. As outlined in the one health Joint Plan of Action, the international one health community includes stakeholders from different sectors. Supported by the Bill & Melinda Gates Foundation, an academic community for one health action has been proposed with the aim of promoting the understanding and real-world implementation of one health approach and contribution towards the Sustainable Development Goals for a healthy planet.Main text The proposed academic community would contribute to generating high-quality scientific evidence, distilling local experiences as well as fostering an interconnected one health culture and mindset, among various stakeholders on different levels and in all sectors. The major scope of the community covers one health governance, zoonotic diseases, food security, antimicrobial resistance, and climate change along with the research agenda to be developed. The academic community will be supported by two committees, including a strategic consultancy committee and a scientific steering committee, composed of influential scientists selected from the one health information database. A workplan containing activities under six objectives is proposed to provide research support, strengthen local capacity, and enhance global participation.Conclusions The proposed academic community for one health action is a crucial step towards enhancing communication, coordination, collaboration, and capacity building for the implementation of one health. By bringing eminent global experts together, the academic community possesses the potential to generate scientific evidence and provide advice to local governments and international organizations, enabling the pursuit of common goals, collaborative policies, and solutions to misaligned interests.

关键词： one health Global health Academic community

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Gut microbiota research nexus:one health relationshipbetween human,animal,and environmental resistomes

引用

mLife 2023年第4期2卷 350-364页

作者： Yuhao Fu Qingyuan Dou Kornelia Smalla Yu Wang Timothy A.Johnson Kristian K.Brandt Zhi Mei Maoyuan Liao Syed A.Hashsham Andreas Schäffer Hauke Smidt Tong Zhang Hui Li Robert Stedtfeld Hongjie Sheng Benli Chai Marko Virta Xin Jiang Fang Wang Yong-Guan Zhu James M.Tiedje State Key Laboratory of Soil and Sustainable Agriculture Institute of Soil ScienceChinese Academy of SciencesNanjingChina University of Chinese Academy of Sciences BeijingChina Julius Kühn Institute(JKI)Federal Research Centre for Cultivated Plants BraunschweigGermany Department of Animal Sciences Purdue UniversityWestLafayetteIndianaUSA Section for Microbial Ecology and Biotechnology Department of Plant and Environmental SciencesUniversity of CopenhagenFrederiksberg CDenmark Sino-Danish Center(SDC) BeijingChina Department of Microbiology University of HelsinkiHelsinkiFinland Department of Plant Soil and MicrobialSciencesCenter for Microbial EcologyMichigan State UniversityMichiganUSA Department of Civil and Environmental Engineering Michigan State UniversityMichiganUSA Institute for Environmental Research RWTH Aachen UniversityAachenGermany Laboratory of Microbiology Wageningen University&ResearchWageningenThe Netherlands Environmental Microbiome Engineering and Biotechnology Laboratory Center for Environmental Engineering ResearchDepartment of Civil EngineeringTheUniversity of Hong KongPokfulamHong KongChina Institute of Agricultural Resources and Environment Jiangsu Academy of Agricultural SciencesNanjingChina KeyLaboratory of Urban Environment and health Institute of Urban EnvironmentChinese Academy of SciencesXiamenChina State Key Laboratory of Urban and Regional Ecology Chinese Academy of SciencesBeijingChina

The emergence and rapid spread of antimicrobial resistance is of global public health concern.The gut microbiota harboring diverse commensal and opportunistic bacteria that can acquire resistance via horizontal and vertical gene transfers is considered an important reservoir and sink of antibiotic resistance genes(ARGs).In this review,we describe the reservoirs of gut ARGs and their dynamics in both animals and humans,use the one health perspective to track the transmission of ARG-containing bacteria between humans,animals,and the environment,and assess the impact of antimicrobial resistance on human health and socioeconomic development.The gut resistome can evolve in an environment subject to various selective pressures,including antibiotic administration and environmental and lifestyle factors(e.g.,diet,age,gender,and living conditions),and interventions through probiotics.Strategies to reduce the abundance of clinically relevant antibiotic-resistant bacteria and their resistance determinants in various environmental niches are needed to ensure the mitigation of acquired antibiotic resistance.With the help of effective measures taken at the national,local,personal,and intestinal management,it will also result in preventing or minimizing the spread of infectious diseases.This review aims to improve our understanding of the correlations between intestinal microbiota and antimicrobial resistance and provide a basis for the development of management strategies to mitigate the antimicrobial resistance crisis.

关键词： antibiotic antimicrobial resistance gut microbiota modulatory strategies one health

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Antimicrobial resistance containment in Africa:Moving beyond surveillance

引用

Biosafety and health 2024年第1期6卷 50-58页

作者： Zikora Kizito Glory Anyaegbunam Ifeanyi Elibe Mba Yandev Doowuese Ngozi J.Anyaegbunam Toluwalase Mba Fetuata Aminat Aina Vincent NnamdigadiChigor Emeka Innocent Nweze Emmanuel A.Ezea Department of Microbiology Faculty of Biological SciencesUniversity of Nigeria Nsukka CampusEnugu 410001Nigeria Department of Pharmaceutical Microbiology Faculty of PharmacyUniversity of IbadanIbadan 20005Nigeria Department of Microbiology Federal University of Health SciencesOtukpo 970001Nigeria Measurement and Evaluation Unit Science Education Department University of Nigeria NsukkaEnugu 410001Nigeria Sumy State University Medical InstituteSumy Oblast 40000Ukraine Lead City University Hospital Lead CityIbadan 200255Nigeria Department of Microbiology College of Natural SciencesFederal University of AgricultureAbeokuta 111101Nigeria

Worldwide,infections caused by drug‐resistant pathogens constitute a significant challenge threatening therapeutic efforts.According to the World health Organization(WHO),antimicrobial resistance(AMR)ranks among the top 10 global public health threats.Organisms with a high rate of multiple host adaptivity,significant genetic diversity(multiple lineages),high virulence factors,and genetic exchange have been isolated from various sources(humans,animals,and the environment)even without exposure to prior antibiotics.Till now,the source of AMR and how resistant clones are selected in the environment remain largely elusive,and potential anthropogenic transmission has been reported in different studies.Various drug‐resistant pathogens,lineages,resistant clones,outbreak clusters,plasmid replicates,and genes that play a critical role in resistance dissemination have been identified.Maintenance of certain multidrug‐resistant(MDR)determinants has also been shown to enhance or support the propagation of MDR.So far,significant advances have been made in understanding the burden of AMR.However,overcoming AMR requires a holistic approach,as there is no single approach with sufficient precision to curb the threat.While strengthening AMR surveillance efforts is essential,as we have shown,there is also a need to intensify efforts to strengthen therapeutic interventions,especially in priority regions such as Africa.Herein,we discussed the burden of AMR and the dissemination of AMR in humans,animals,and the environment(non‐medical drivers).We further delved into the big questions on Africa and discussed how therapeutic interventions involving vaccines and other viable biomaterials could be pivotal in reducing the burden of AMR to the barest minimum.

关键词： Antimicrobial resistance(AMR) Bacteria Surveillance one health Vaccines Africa

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Roadmap to tackle antibiotic resistance in the environment under the one health framework

引用

mLife 2023年第3期2卷 224-228页

作者： Liguan Li Tong Zhang Environmental Microbiome Engineering and Biotechnology Laboratory Center for Environmental Engineering ResearchDepartment of Civil EngineeringThe University of Hong KongHong KongChina

Antibiotic resistance has been recognized as a major challenge worldwide for humans.“one health”has been recognized as a key concept for containment of antibiotic resistance.Under the framework,the role of the environment in the development of antibiotic resistance genes(ARGs)has become increasingly obvious.Despite numerous efforts,response to antibiotic re-sistance is considered to be inadequate,which is probably due to the lack of a clear roadmap.Here,we propose a“one health”roadmap to combat antibiotic resistance in the environment through(1)understanding environmental resistome.The environmental gene pool has long been recognized as the single largest reservoir of both known and novel ARGs.(2)Standardizing ARG quantification.Systematic joint efforts based on standardized quantification are urgently needed to un-derstand the true tempospatial profiles of the environmental resistome.(3)Identifying mechanisms of resistome development.Horizontal gene transfer and co-selection have been recognized as the two main mechanisms contributing to the environmental resistome.(4)Establishing a risk-assessment framework.The first critical step for large-scale cost-effective targeted ARG management in the environment is the risk assessment to identify the priority ARGs for control.(5)Formulating regulatory standards.By correlating the environmental ARG profile with public health,we may identify the indicator ARGs that can be integrated into current environmental quality standards.(6)Developing control strategies.Systematic analysis of available control technologies is required to identify the most feasible ones to curtail the spread of ARGs in the environment.The proposed roadmap under the“one health”framework provides a guide to tackle antibiotic resistance in the environment.

关键词： antibiotic resistance environment one health roadmap

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：