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ocular complications in Diabetic Patients: Prevalence, Impact on Quality of Life, and Implications for Healthcare

Open Journal of Ophthalmology 2024年第2期14卷 149-158页

作者： Prudence Ada Assoumou Davy Alex Mouinga Abayi Daniella Nsame Annick Kougou Ntoutoume Hélène Nyinko Aboughe Olive Matsanga Tatiana Harly Mba Aki Emmanuel Mve Mengome Owendo University Hospital Center Department of Surgery at the Faculty of Medicine of the University of Health Sciences Libreville Gabon Omar Bongo Ondimba Military Instructions Hospital Department of Surgery at the Faculty of Medicine of the University of Health Sciences Libreville Gabon Endocrinology Department at the Libreville Hospital Center Department of Internal Medicine at the Faculty of Medicine of the University of Health Sciences Libreville Gabon Jeanne Ebori Foundation Mother and Child University Hospital Center Department of Surgery at the Faculty of Medicine of the University of Health Sciences Libreville Gabon

Introduction: Diabetes, a chronic disease characterized by persistent hyperglycemia, poses a major global health challenge. In Gabon, 10% of the population is affected by this condition, highlighting the need to actively understand and manage it. ocular complications of diabetes, including diabetic retinopathy, glaucoma, and cataracts, have a devastating impact on patients quality of life and represent a crucial issue for healthcare systems. Methodology: This study conducted in Libreville from February 9, 2022, to April 15, 2022, was cross-sectional, longitudinal, and descriptive, with prospective data collection. Participants were diabetic patients regularly followed in the endocrinology department of CHUL, who were referred for a comprehensive ophthalmological examination at CHUO. Sampling was exhaustive, with strict inclusion criteria aimed at ensuring the representativeness of the study population. Results: The mean age of participants was 57.5 ± 13.2 years with a male-to-female ratio of 0.8. Personal histories were dominated by hypertension, while family histories were dominated by diabetes. ocular complications of diabetes included refractive disorders (78.9%), cataracts (31.7%), glaucoma (78.9%), and diabetic retinopathy (13.7%). These ocular complications had a significant impact on participants’ quality of life, leading to impaired vision (78.9%), difficulties in carrying out daily activities (62.2%), the need for caregiver assistance (50.3%), high levels of stress and anxiety (68.9%), regular medication intake (71.4%), adherence to a specific diet (55.9%), and frequent blood glucose monitoring (74.5%). Conclusion: This study highlights the major impact of diabetic ocular complications on patients’ quality of life.

关键词： ocular complications Diabetes Quality of Life Prevalence Gabon

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Ophthalmic manifestations in patients with inflammatory bowel disease: a review

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World Journal of Gastroenterology 2017年第32期23卷 5836-5848页

作者： Leandro Lopes Troncoso Ana Luiza Biancardi Haroldo Vieira de Moraes Jr Cyrla Zaltman Department of Ophthalmology Universidade Federal do Rio de Janeiro Department of Internal Medicine Gastroenterology DivisionUniversidade Federal do Rio de Janeiro

Clinical manifestations of inflammatory bowel disease(IBD) are not locally restricted to the gastrointestinal tract, and a significant portion of patients have involvement of other organs and systems. The visual system is one of the most frequently affected, mainly by inflammatory disorders such as episcleritis, uveitis and scleritis. A critical review of available literature concerning ocular involvement in IBD, as it appears in Pub Med, was performed. Episcleritis, the most common ocular extraintestinal manifestation(EIM), seems to be more associated with IBD activity when compared with other ocular EIMs. In IBD patients, anterior uveitis has an insidious onset, it is longstanding and bilateral, and not related to the intestinal disease activity. Systemic steroids or immunosuppressants may be necessary in severe ocular inflammation cases, and control of the underlying bowel disease is important to prevent recurrence. Our review revealed that ocular involvement is more prevalent in Crohn's disease than ulcerative colitis, in active IBD, mainly in the presence of other EIMs. The ophthalmic symptoms in IBD are mainly nonspecific and their relevance may not be recognized by the clinician; most ophthalmic manifestations are treatable, and resolve without sequel upon prompt treatment. A collaborative clinical care team for management of IBD that includes ophthalmologists is central for improvement of quality care for these patients, and it is also cost-effective.

关键词： Inflammatory bowel disease Crohn's disease Ulcerative colitis ocular complications Eye manifestations

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The impact of combined oral contraceptives on ocular tissues:a review of ocular effects

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International Journal of Ophthalmology(English edition) 2017年第10期10卷 1604-1610页

作者： Marilita M.Moschos Eirini Nitoda Department of Ophthalmology Medical SchoolNational & Kapodistrian University of Athens

The aim of this manuscript is to review the action and adverse effects of combined oral contraceptives（COCs）on ocular *** percentage of unwanted pregnancies and the subsequent abortions make contraception crucial *** 100 million women around the world use common contraceptive methods,including intrauterine devices,combined estrogen and progestin oral contraceptives,as well as progestin only preparations（oral contraceptives,implants or injections）.COCs are widely used for contraception,but they are also indicated in menorrhagia,endometriosis,acne and hirsutism,fibroid uterus and premenstrual ***,they have been associated with high rates of cardiovascular events,venous thromboembolic disease,ischemic strokes and breast *** incidence of COCs-related ocular complications is estimated to be 1 in 230 000,including dry eye symptoms,corneal edema,lens opacities and retinal neuro-ophthalmologic or vascular *** may infer that the serious ocular complications of COCs can be prevented by eliminating the estrogen dosage and choosing third-generation *** any case,doctors should take into consideration the systemic and ocular history of the patients before selecting any method of contraception.

关键词： adverse effects ocular complications oral contraceptives

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Determinants of the Ophthalmological Follow-Up of Sickle Cell Patients at the National Center of Research and Care for Sickle Cell Patients in Lome-Togo

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Open Journal of Ophthalmology 2023年第4期13卷 341-351页

作者： Nidain Maneh Yawa Edebah Nagbe Mawuli Ayodele Komi Santos Dadjo Amouzou Hezouwe Magnang Koffi Sylvain Kawilitetou Kokou Messan Amedome Komi Patrice Balo Service d’Ophtalmologie du CHU-Campus Université de Lome Lomé Togo Service d’Ophtalmologie du CHU Sylvanus Olympio Université de Lome Lomé Togo Service d’Ophtalmologie CHP Université de Lomé FSS Aného Togo Département des sciences fondamentales CNRSD Lomé Togo Service d’ophtalmologie du CHU Université de Kara FSS Kara Togo

Objectives: To assess the factors influencing the ophthalmological follow-up of sickle cell patients in Togo. Materials and Methods: The national center of research and care for sickle cell patients (CNRSD) served as study setting. It was a descriptive and analytical study by interview over a three-month period from December 01, 2020 to March 02, 2021. Was included in the study, any patient with sickle cell disease genotype SS or SC, age ≥ 17 years, regularly followed at the CNRSD and having accepted the interview by a survey sheet. Excluded were patients with sickle cell trait genotype AS or AC or with a disability that prevented them from being interviewed. Results: Two hundred and fifty (250) patients with sickle cell disease were interviewed. The mean age was 29.1 years ± 11.12 years [17 years;67 years] and the sex ratio = 0.52. Nine patients over ten (9/10) attended at least secondary school. The jobless represented 25.60% of the total population followed respectively by students and laborers in 20.40% and 16% of cases. Twenty-four percent (24%) of patients were followed up in ophthalmology department. Statistically, there was no significant relationship between level of education (p = 0.4083), occupation (p = 0.6441) and knowledge of the ocular complications of sickle cell disease. Statistically, there was a significant relationship between knowledge of the ocular complications of sickle cell disease and compliance with ophthalmological follow-up (p = 0.0009). Conclusion: The knowledge of eye disorders related to sickle cell disease by patients with sickle cell disease improves their ophthalmological follow-up. Greater awareness on eye disorders related to sickle cell disease by medical staff towards patients with sickle cell disease would improve ophthalmological follow-up. .

关键词： Ophthalmological Follow-Up Sickle Cell Patient ocular complications Lome

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