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Effects of ovarian response prediction index and follicle-oocyte index on pregnancy outcomes: a retrospective cohort study of 12,218 fresh transfer cycles

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REPRODUCTIVE AND DEVELOPMENTAL MEDICINE 2024年第3期8卷 151-161页

作者： Wang, Mao Tan, Li Ding, Yu-Bin Tang, Xiao-Jun Li, Tian Hu, Xin-Yue Zhong, Hu-Cen Wan, Qi Zhong, Zhao-Hui Chongqing Med Univ Res Ctr Med & Social Dev Innovat Ctr Social Risk Governance Hlth Dept EpidemiolSch Publ Hlth Chongqing 400016 Peoples R China Chongqing Med Univ Sch Publ Hlth Joint Int Res Lab Reprod & Dev Minist Educ China Chongqing 400016 Peoples R China Chengdu Xinan Gynecol Hosp Reprod Ctr Chengdu 610011 Peoples R China Sichuan Univ West China Hosp 2 Dept Gynecol & Obstet Chengdu 610041 Peoples R China Changsha Med Univ Dept Pharmacol Academician Workstat Changsha 410219 Peoples R China Chongqing Med Univ Dept Reprod Med Affiliated Hosp 1 Chongqing 400016 Peoples R China

Objective: To investigate the potential relationships among the ovarian response prediction index (ORPI), follicle-oocyte index (FOI), and clinical pregnancy rate (CPR) in women undergoing their first in vitro fertilization/intracytoplasmic sperm injection-embryo transfer (IVF/ICSI-ET) fresh cycle transfer. Methods In this retrospective cohort study, we included 12,218 women who underwent their first IVF/ICSI-ET cycle between December 2014 and January 2021. The primary and secondary outcomes of our study were CPR and cumulative live birth rate (CLBR), respectively. The data were divided into three groups according to the ORPI and FOI tertiles. Multivariate logistic regression analyses, stratification analyses, interaction, restricted cubic splines, and receiver operating characteristic (ROC) curves were constructed to identify the relationships among ORPI, FOI, and CPR. Results: A statistically significant increase in CPR was detected from the lowest to the highest tertile group (ORPI: 48.12%, 54.07%, and 53.47%, P <0.001; FOI: 49.99%, 52.95%, and 52.71%, P = 0.012). A higher CLBR was observed in the high group (ORPI: 38.63%, 44.62%, and 44.19%, P <0.001; FOI: 41.02%, 43.78%, and 42.59%, P = 0.039). Multivariate logistic regression analysis revealed no statistically significant differences between ORPI, FOI, and neither CPR (odds ratio [OR] [95% confidence interval {CI}], 0.99 [0.97-1.00] vs. [1.02 {0.84-1.24}]) nor CLBR (OR [95% CI], 0.99 [0.97-1.01] vs. 0.99 [0.81-1.20]). No significant association was found among FOI, ORPI, and CPR, even in the subgroups. Restricted cubic spline analyses indicated the existence of a non-linear relationship across the entire range of FOI and ORPI. The ORPI and FOI variables had poor predictive ability (AUC < 0.60) for CPR. Conclusions: Both ORPI and FOI are not reliable predictors of clinical pregnancy or live birth outcomes in fresh ETs. Clinicians and researchers should avoid using FOI and ORPI to assess pregnancy outcomes after

关键词： In vitro fertilization Controlled ovarian hyperstimulation Ovarian response indexes Ovarian response prediction index Follicle-oocyte index Clinical pregnancy ASSISTED REPRODUCTIVE TECHNOLOGY LIVE BIRTH-rateS output rate STIMULATING-HORMONE WOMEN COUNT

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Estimation of ammonia nitrogen load from nonpoint sources in the Xitiao River catchment, China

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Journal of Environmental Sciences 2008年第10期20卷 1195-1201页

作者： LIANG Tao WANG Shanna CAO Hongying ZHANG Chaosheng LI Haitao LI Hengpeng SONG Wenchong CHONG Zhongyi Institute of Geographic Sciences and Natural Resources Research Chinese Academy of Sciences Beijing 100101 China Department of Geography National University of Ireland Galway Ireland Nanjing Institute of Geography & Limnology Chinese Academy of Sciences Nanjing 210008 China

Ammonia nitrogen (NH4+-N) is one of the three main forms of total nitrogen (TN). Most studies have estimated the load of TN from nonpoint sources instead of one specific form. The relationship between land use and concentrations of NH4+-N in runoff was analyzed using the hydraulic analysis functions of a Geographic Information Systems (GIS), and the annual loads of NH4+-N in the Xitiao River catchment were estimated according to model results. The results suggested that the calculated annual loads of NH4+-N...

关键词： nonpoint source pollution NH4+-N Geographic Information systems (GIS) output rate load

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