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nutritional evaluation,fatty acid analysis and anticancer properties investigation of seeds from kan-zaw,a potential diet oil and medicinal plant

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Oil Crop Science 2021年第3期6卷 122-127页

作者： Moe Moe Lwin Ye Jin Xianpeng Yang Hao Shen Chao Qi Yizhong Wang Phyo Phyo Zin Oo Za Khai Tuang Shiyou Lü Wannian Yang Hubei Key Laboratory of Genetic Regulation and Integrative Biology School of Life SciencesCentral China Normal UniversityWuhan430079PR China Department of Botany Kyaing Tong UniversityEastern Shan StateMyanmar College of Life Sciences Shandong Normal UniversityJinan250014PR China School of Life Sciences Hubei UniversityWuhan434200PR China

Payenapara lleloneura Kurz.(Kan-zaw),an endemic medicinal plant only found in Tanintharyi Region of Myanmar,is widely used in the treatment of various cancer and different *** the present research,the seeds were phytochemical investigated for their nutritional potential for their use as functional foods or novel diet oil *** evaluation showed that the seeds are rich in fats and carbohydrates(soluble sugars and starch).Fatty acid analyses showed that the seeds accumulate very richα-eleostearic acid(α-ESA,18:3^(Δ9 cis,11-trans),13 trans),an important conjugated fatty acid,up to more than 70% of total fatty *** seed oil derived from the Kan-zaw tree contains approximately 3.25% β-eleostearic acid(18:3^(Δ9 trans,11 trans,13 trans)),an unusual conjugated fatty acid that imparts a potent anticancer application and industrially important drying qualities to Kan-zaw *** properties of the Kan-zaw seeds were examined;petroleum ether(60–90℃)extract of seed oils were also investigated for the saponification value,iodine value and estimation of acid ***,the present study investigated cytotoxic potential of ethanol,methanol,acetone,chloroform Kan-zaw seed extracts and commercial Kan-zaw oil against human cervical cancer cell line(HeLa).The Kan-zaw extracts and oil have shown significant anticancer activity on HeLa cells.

关键词： Payenapara lleloneura Kurz. Kan-zaw seeds nutritional evaluation Fatty acid analysis Physicochemical properties Anticancer activity

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Progresses on Personalized nutritional evaluation and Recommendation

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Journal of Animal Science and Biotechnology 2010年第3期1卷 182-193页

作者： Gang Lin Chuang Liu Huaijun Zhou Shuo Feng Yiqiang Chen Luoyun Fang Guoyao Wu Jing Zhang Shiyan Qiao Junjun Wang State Key Laboratory of Animal Nutrition College of Animal Science and Technology China Agricultural University Beijing 100193 China Department of Poultry Science and Faculty of Genetics Texas A&M University College Station TX 77843 USA Department of Statistics Texas A&M University College Station TX 77843 USA Department of Animal Science Beijing University of Agriculture Beijing 102206 China Department of Animal Science and Faculty of Nutrition Texas A&M University College Station TX 77843 USA Department of Animal Science College of Animal Science and Veterinary Medicine Jilin University Changchun JiLin 130062 China

Health is maintained by a state of dynamic homeostasis in which nutrient intake and ex- penditure are of good balance. Therefore, it is important to know exactly the nutritional value of food sources, as well as the nutritional requirements of individuals, in order to achieve optimal nutrition. Considering the interaction between diet and individual back- ground, nutritional evaluation and recommendation has become a complicate issue needing further investigations. While traditional nutrition research has made significant progress in population nutrition, modern nutrition research is now becoming possible to focus on personalized nutrition in health promotion, disease prevention, performance improvement, and risk assessment of individual with the development of emerging omics technologies. This review tried to summarize the methods used in nutritional evaluation and recom- mendation as well as their applications. Though personal nutrition evaluation and recommendation are still not well-established, utilization of these advanced technologies may expand our knowledge in bioavailability and bioefficacy of diet ingredients, pathophysiological changes in response to dietary intervention, as well as nutrition-associated disease biomarkers discovery, and thus contributing to personalized nutrition.

关键词： nutritional evaluation nutritional recommendation personalized nutrition

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Biofortification of rice with the essential amino acid lysine

Biofortification of rice with the essential amino acid lysin...

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江苏省遗传学会2017年学术研讨会——“技术创新与遗传...

作者： Hong-Yu Wu Qing-Qing Yang Qiao-Quan Liu Key Laboratory of Crop Genetics and Physiology of Jiangsu Province/Key Laboratory of Plant Functional Genomics of the Ministry of Education College of Agriculture Yangzhou University Co-Innovation Center for Modern Production Technology of Grain Crops of Jiangsu Province/Joint International Research Laboratory of Agriculture and Agri-Product Safety of the Ministry of Education Yangzhou University

Rice（Oryza sativa L.）, a major staple crop worldwide, has limited levels of the essential amino acid lysine. We previously produced engineered rice with increased lysine content by expressing bacterial aspartate kinase and dihydrodipicolinate synthase and inhibiting rice lysine ketoglutarate reductase/saccharopine dehydrogenase activity. However, the grain quality, field performance, and integration patterns of the transgenes in these lysineenriched lines remain unclear. We selected several elite transgenic lines with endospermspecific or constitutive regulation of the above key enzymes but lacking the selectable marker gene. All target transgenes were integrated into the intragenic region in the rice genome. Two pyramid transgenic lines（High Free Lysine;HFL1 and HFL2） with free lysine levels in seeds up to 25-fold that of wild type were obtained via a combination of the above two transgenic events. We observed a dramatic increase in total free amino acids and a slight increase in total protein content in both pyramid lines. Moreover, the general physicochemical properties were improved in pyramid transgenic rice, but the starch composition was not affected. Field trials indicated that the growth of HFL transgenic rice was normal, except for a slight difference in plant height and grain colour. Then, a 70-day rat feeding study was conducted to assess the nutritional value of HFL1 and HFL2 lines as compared with either their wild type, lysinebiofortified rice contributed to improved growth performance, food efficiency, and lysine availability in growing rats. These findings will be useful for the potential commercialization of high-lysine transgenic rice.

关键词： rice(Oryza sativa L.) lysine metabolic engineering nutritional evaluation

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