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Safety of applying midazolam-ketamine-propofol sedation combination under the supervision of endoscopy nurse with patient-controlled analgesia pump in colonoscopy

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World Journal of Clinical Cases 2018年第16期6卷 1146-1154页

作者： Selda Kayaalt? mer Kayaalt? Division of Anaesthesiology and Reanimation Develi Public Hospital Computer Technology Kayseri University Develi Huseyin Sahin Vocational College

AIM To compare the results of midazolam-ketaminepropofol sedation performed by an endoscopy nurse and anaesthetist during colonoscopy in terms of patient satisfaction and *** American Statistical Association(ASA) Ⅰ-Ⅱ 60 patients who underwent colonoscopy under sedation were randomly divided into two groups: sedation under the supervision of an anaesthetist(SSA) and sedation under the supervision of an endoscopy nurse(SSEN). Both groups were initially administered 1 mg midazolam, 50 mg ketamine and 30-50 mg propofol. Continuation of sedation was performed by the anaesthetist in the SSAgroup and the nurse with a patient-controlled analgesia(PCA) pump in the SSEN group. The total propofol consumption, procedure duration, recovery times, pain using the visual analogue scale(VAS) and satisfaction score of the patients, and side effects were recorded. In addition, the patients were asked whether they remembered the procedure and whether they would prefer the same method in the case of *** Total propofol consumption in the SSEN group was significantly higher(P 0.05) between the two groups. No long-term required intervention side effects were observed in either *** Colonoscopy sedation in ASA Ⅰ-Ⅱ patients can be safely performed by an endoscopy nurse using PCA pump with the incidence of side effects and patient satisfaction levels similar to sedation under anaesthetist supervision.

关键词： Midazolam-ketamine-propofol combination Patient-controlled analgesia pump nurse-administered sedation Colonoscopy

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