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normothermic regional perfusion mobile teams in controlled donation after circulatory death pathway: Evidence and peculiarities

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World Journal of Transplantation 2024年第4期14卷 78-83页

作者： Chiara Lazzeri Manuela Bonizzoli Giuseppe Feltrin Adriano Peris Department of Emergency Extracorporeal Membrane Oxygenation CenterRegional Transplant CenterFlorence 50134Italy Department of Emergency Extracorporeal Membrane Oxygenation CenterFlorence 50134Italy Centro Nazionale Trapianti Roma 00161Italy

To facilitate the implementation of controlled donation after circulatory death(cDCD)programs even in hospitals not equipped with a local Extracorporeal Membrane Oxygenation(ECMO)team(Spokes),some countries and Italian Regions have launched a local cDCD network with a ECMO mobile team who move from Hub hospitals to Spokes for normothermic regional perfusion(NRP)implantation in the setting of a cDCD *** ECMO teams have been clearly defined by the Extracorporeal Life Support Organization,regarding composition,responsibilities and training programs,no clear,widely accepted indications are to date available for NRP *** existing NRP mobile networks were developed due to the urgent need to increase the number of cDCDs,there is now the necessity for transplantation medicine to identify the peculiarities and responsibility of a NRP team for all those centers launching a cDCD ***,in the present manuscript we summarized the character-istics of an ECMO mobile team,highlighting similarities and differences with the NRP mobile *** also assessed existing evidence on NRP teams with the goal of identifying the characteristic and essential features of an NRP mobile team for a cDCD program,especially for those centers who are starting the *** were identified between the mobile ECMO team and NRP mobile *** common essential feature for both mobile teams is high skills and experience to reduce complications and,in the case of cDCD,to reduce the total warm ischemic *** training programs should be developed for the launch of de novo NRP teams.

关键词： Controlled donation after circulatory death Extracorporeal membrane oxygenation normothermic regional perfusion Mobile teams Warm ischemia time

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