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noninfectious Fever Following Aortic Surgery:Incidence,Risk Factors,and Outcomes

Chinese Medical Sciences Journal 2009年第4期24卷 213-219页

作者： Yun-tai Yao Li-huan Li Qian Lei Lei Chen Wei-peng Wang Wei-ping Chen Department of Anesthesiology Fuwai Cardiovascular Hospital Chinese Academy of Medical Sciences ＆ Peking Union Medical College Beijing 100037 China

Objective To determine the incidence, course, potential risk factors, and outcomes of noninfectious fever developed in patients after aortic surgery. Methods Patients who received operation for aortic aneurysm or dissection in our center from January 2006 to January 2008 were reviewed. Patients who met one of the following criteria were excluded： having a known source of infection during hospitalization; having a preoperative oral temperature greater than or equal to 38.0℃; undertaking emergency surgery; having incomplete data. Univariate analysis was performed in patients with noninfectious postoperative fever and those without, with respect to demographics, intraoperative data, etc. Risk factors for postoperative fever were considered for the muhivariate logistic regression model if they had a P value less than 0.10 in the univariate analysis. Results Totally 463 patients undergoing aortic surgery were enrolled for full review. Among them, 345 （74.5%） patients had noninfectious postoperative fever, the other 118 （25.5%） patients didn＇t develop postoperative fever. Univariate analysis demonstrated that several risk factors were associated with the development of noninfectious postoperative fever, including weight, surgical procedure, minimum intraoperative bladder temperature, temperature upon intensive care unit （ICU） admission, discharge, and during ICU stay, as well as blood transfusion. In a further multivariate analysis, surgical site of thoracic and thoracoabdominal aorta （odds ratio： 4.861; 95% confidence interval： 3.029-5.801; P=0.004）, lower minimum intraoperative bladder temperature （odds ratio： 1.117; 95% confidence interval： 1.01-1.24; P=0.04）, and higher temperature on admission to the ICU （odds ratio： 2.57; 95% confidence interval： 1.28-5.18; P=0.008） were found to be significant predictors for noninfectious postoperative fever. No difference was found between the febrile and afebrile patients with regard to postoperative hospitalization duration （P

关键词： fever noninfectious aortic surgery

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Current management of noninfectious hepatic cystic lesions:A review of the literature

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World Journal of Hepatology 2013年第9期5卷 462-469页

作者： Francisco Igor Macedo Department of Surgery Providence Hospital and Medical CentersSouthfieldMI 48075United States

Nonparasitic hepatic cysts consist of a heterogeneous group of disorders, which differ in etiology, prevalence,and manifestations. With improving diagnostic techniques, hepatic cysts are becoming more *** advancements in minimally invasive technology created a new Era in the management of hepatic cystic disease. Herein, the most current recommendations for management of noninfectious hepatic cysts are described, thereby discussing differential diagnosis, new therapeutic modalities and outcomes.

关键词： simple hepatic cyst noninfectious Polycystic liver disease Cystadenoma Cystadenocarcinoma Caroli’s disease sclerotherapy Fenestration

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Clinical Significance of Pulmonary Function Tests in Long-Term Survivors after Myeloablative Allogeneic Hematopoietic Stem Cell Transplantation

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Open Journal of Blood Diseases 2013年第1期3卷 6-12页

作者： Kenji Matsumoto Satomi Ito Wataru Yamamoto Eriko Ogusa Atsuo Maruta Yoshiaki Ishigatsubo Heiwa Kanamori Department Internal Medicine and Clinical Immunology Yokohama City University Graduate School of Medicine Yokohama Japan. Department of Hematology Kanagawa Cancer Center Yokohama Japan

We retrospectively assessed long-term pulmonary function in adults surviving for ≥5 years after myeloablative allogeneic hematopoietic stem cell transplantation and identified risk factors for late-onset noninfectious pulmonary complications. Among 174 patients undergoing transplantation for hematologic malignancies between May 1994 and December 2004, 81 long-term survivors were evaluated. Pulmonary function tests (PFTs) were performed before conditioning, 3 months and 1 year after transplantation, and then annually. Eight patients (10%) had abnormal pulmonary function before transplantation, but this was not associated with late changes in PFTs. Patients with chronic graft-versus-host disease (GVHD) showed a significant decline of lung function after 3 years when compared with patients without chronic GVHD. Abnormal pretransplantation lung function was associated with pulmonary chronic GVHD according to National Institutes of Health criteria (score 0, n = 58;score 1, n = 14;score 2, n = 6;score 3, n = 3). Five patients with late-onset noninfectious pulmonary complications showed a decline of lung function at 1 year after transplantation. Only chronic GVHD was significantly related to late-onset noninfectious pulmonary complications. In conclusion, abnormal lung function before transplantation may be associated with a decline in pulmonary function within 1 year after transplantation, but late-onset noninfectious pulmonary complications could not be predicted from pretransplantation lung function.

关键词： Long-Term Survivor Pulmonary Function Tests Late-Onset noninfectious Pulmonary Complications Myeloablative Allogeneic Stem Cell Transplantation

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