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Manual and alternative therapies as non-pharmacological interventions for pain and stress control in newborns:a systematic review

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World Journal of Pediatrics 2023年第1期19卷 35-47页

作者： Leva A.Shayani Vera Regina F.da S.Maraes University of Brasilia BrasiliaBrazil

Background Supporting therapies that provide stress and pain control of preterm and term newborns infants contribute positively to the neuropsychomotor ***-pharmacological interventions that involve manual techniques are described,considering protocols that can be reproduced by physical therapists,with positive and negative outcomes *** sources Systematic review follows PRISMA 2020 statements *** and specific health sciences databases(Science Direct,Pubmed,Scielo,Embase and Scopus)were consulted between October 2021 and May *** con-sidered were clinical trials,randomized or not,that included descriptions of the type of intervention as non-pharmacological and that studied the following outcomes:"pain"and"stress".Results Fifteen articles were selected for analysis,reaching a methodological quality of at least 3 on the Jadad Scale for the Quality of Researched *** non-pharmacological therapies most applied in isolation were massage,swaddling or wrapping,gentle touch and kinesthetic stimulation,and the combined therapies were non-nutritive sucking and swad-dling,oral sucrose and swaddling,sensory stimulation and familiar odors,and sensory *** outcomes found were relaxation,pain,and stress reduction after the application of painful *** behavioral changes included crying,grimacing,yawning,sneezing,jerky arm or leg movements,startles,and finger *** vital signs included heart rate,blood oxygen saturation level,and pulse *** Combined techniques lead to better results in controlling neonatal pain when compared to isolated *** can be applied both in preterm and term infants in a safe way and are reproducible in any health unit in a simple and economical way.

关键词： Newborn non-pharmacological interventions Pain Premature neonate Stress

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Research progress in prevention of postoperative delirium

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Journal of Translational Neuroscience 2023年第4期8卷 1-6页

作者： Xueqi Fan Xi Wang Zihan Chu Ning Wang Chinese Academy of Medical Science and Peking Union Medical College Beijing 100005China Center for Health Quality National Research Institute for Family PlanningBeijing 100081China College of Sciences Northeastern UniversityShenyang 110000China

Postoperative delirium is a common acute confusion state that frequently occurs in patients following *** is characterized by fluctuating consciousness,inattention,disorganized thinking,and altered level of *** delirium leads to cognitive decline and dementia,increases the risk of post-operative complications and mortality,and reduces patients’quality of *** the pathogenesis of postoperative delirium is unclear and there is no effective treatment,early diagnosis and early intervention are key to preventing and treating postoperative ***,the prevention of postoperative delirium is mainly based on non-pharmacological prevention and treatment,whereas some drugs are gradually starting to be *** the future,efforts are needed to clarify the effect of treatment and to guide the development of a series of more effective and rational delirium treatment strategies adapted to specific national context.

关键词： postoperative delirium prevention pharmacological interventions non-pharmacological interventions

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