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The use of non-living animals as simulation models for cranial neurosurgical procedures: a literature review

Chinese Neurosurgical Journal 2020年第4期6卷 230-234页

作者： Zahraa F.Al-Sharshahi Samer S.Hoz Mohammed A.Alrawi Mohammed A.Sabah Saja A.Albanaa Luis Rafael Moscote-Salazar Department of Neurosurgery Neurosurgery teaching HospitalBaghdadIraq College of Medicine University of BaghdadBaghdadIraq RED LATINO Latin American Trauma&Intensive Neuro-Care OrganizationBogotáColombia

Simulation plays a pivotal role in neurosurgical training by allowing trainees to develop the requisite expertise to enhance patient safety.Several models have been used for simulation purposes.non-living animal models offer a range of benefits,including affordability,availability,biological texture,and a comparable similarity to human anatomy.In this paper,we review the available literature on the use of non-living animals in neurosurgical simulation training.We aim to answer the following questions:(1)what animals have been used so far,(2)what neurosurgical approaches have been simulated,(3)what were the trainee tasks,and(4)what was the experience of the authors with these models.A search of the PubMed Medline database was performed to identify studies that examined the use of non-living animals in cranial neurosurgical simulation between 1990 and 2020.Our initial search yielded a total of 70 results.After careful screening,we included 22 articles for qualitative analysis.We compared the reports in terms of the(1)animal used,(2)type of surgery,and(3)trainee tasks.All articles were published between 2003 and 2019.These simulations were performed on three types of animals,namely sheep,cow,and swine.All authors designed specific,task-oriented approaches and concluded that the models used were adequate for replicating the surgical approaches.Simulation on non-living animal heads has recently gained popularity in the field of neurosurgical training.non-living animal models are an increasingly attractive option for cranial neurosurgical simulation training.These models enable the acquisition and refinement of surgical skills,with the added benefits of accessibility and cost-effectiveness.To date,16 different microneurosurgical cranial approaches have been replicated on three non-living animal models,including sheep,cows,and swine.This review summarizes the experience reported with the use of non-living animal models as alternative laboratory tools for cranial neurosurgical training,with particular attention to the se

关键词： Neurosurgery Cranial Simulation non-living Sheep Swine Cow

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On the Importance of ATP Energy in Biology with Regard to Viruses

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Open Journal of Biophysics 2021年第3期11卷 225-232页

作者： Fritz Lewertoff Service de Recherche Pédagogique Québec Canada

Even today in light of the pandemic spread of the corona virus COVID 19, the debate amongst biologists which concerns whether viruses are alive or not still remains unresolved. This, however, revolves around the argument that viruses cannot produce their own adenosine triphosphate molecule (ATP) through metabolism and, therefore, must rely on other living microorganisms that can produce it in order to access the energy that ATP provides upon hydrolysis. It is mainly on account of this distinction that viruses are relegated to an ill-defined area that separates living things from nonliving things. Nevertheless, apparently viruses possess an inherent capacity that enables them to cross this invisible dividing line in order to link up with the ATP molecule through which they sustain their activities. The following presents a review of these issues with regard to microbiology, biochemistry and physics.

关键词： ATP Virus Autonomy Collaboration Lineage Formation living non-living Metabolic Whole

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