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Acute inferior myocardial infarction in a young man with testicular seminoma:A case report

World Journal of Clinical Cases 2021年第16期9卷 4040-4045页

作者： Alexandru Scafa-Udriste Nicoleta-Monica Popa-Fotea Vlad Bataila Lucian Calmac Maria Dorobantu Department of Cardio-Thoracic University of Medicine and PharmacyBucharest 050474Romania Department of Cardiology Emergency Clinical HospitalBucharest 014461Romania

BACKGROUND Atherosclerosis represents the main cause of myocardial infarction(MI);other causes such as coronary embolism,vasospasm,coronary-dissection or drug use are much rarely encountered,but should be considered in less common clinical *** young individuals without cardiovascular risk factors,the identification of the cause of MI can sometimes be found in the medical history and previous treatments *** SUMMARY We present the case of a 34-year-old man presenting acute inferior ST-elevation MI without classic cardiac risk *** years ago,he suffered from orchidopexy for bilateral cryptorchidism,and was recently diagnosed with right testicular seminoma for which he had to undergo surgical resection and chemotherapy with bleomycin,etoposide and *** after the first chemotherapy treatment,namely on day five,he suffered an acute *** revealed a mild stenotic lesion at the level of the right coronary artery with suprajacent thrombus and vasospasm,with no other significant lesions on the other coronary arteries.A conservative treatment was decided upon by the cardiac team,including dual antiplatelets therapy and anticoagulants with good further *** patient continued the chemotherapy treatment according to the initial plan without other cardiovascular *** In young individuals with no cardiovascular risk factors undergoing aggressive chemotherapy,an acute MI can be caused by vascular toxicity of several anticancer drugs.

关键词： Testicular seminoma myocardial infarction non-atherosclerotic causes of myocardial infarction Chemotherapy Case report

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