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New Cutoff for High Sensitivity Troponin to Better Risk Stratify Patients with non-ST Elevated myocardial infarction

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World Journal of Cardiovascular Diseases 2021年第1期11卷 25-33页

作者： Omar Y. Al-Assaf Anas Musa Hind H. Alkazim Sam C. Benny Azan S. Binbrek Internal Medicine Department Rashid Hospital Dubai Health Authority Dubai United Arab Emirates Cardiology Department Rashid Hospital Dubai Health Authority Dubai United Arab Emirates

Background: The diagnosis of non-ST Elevated myocardial infarction (NSTEMI) is dependent on elevation of high sensitivity troponin (Hs-troponin). The current cutoff point for Hs-troponin is highly sensitive but not sp... 详细信息

Background: The diagnosis of Non-ST Elevated Myocardial Infarction (NSTEMI) is dependent on elevation of high sensitivity troponin (Hs-troponin). The current cutoff point for Hs-troponin is highly sensitive but not specific for obstructive coronary artery disease (CAD). This study aims to determine the best cutoff point for diagnosing CAD in patients presented with NSTEMI. Methods: Our study included all patients admitted as NSTEMI that underwent coronary angiography (CAG). They were grouped into two groups: A and B. Group A has obstructive CAD of 70% or more stenosis and group B with non-obstructive CAD. Patients were assessed for their demographics, clinical history, laboratory and imaging results. Using SPSS version 22, the pooled cohort of patients were analyzed at significant level 0.05 and the data were tested for significant correlations between two predetermined groups. Results: Group A comprised 87.6% of the patients and both groups had a median age of 53 years. In Group A, 91% were males, 54% diabetics, 54% hypertensives, and median Hs-troponin was 145 ng/L. While in group B, 88% were males, 39% diabetics, 60% hypertensives, and median Hs-troponin was 54 ng/L. There was significant correlation between the two groups in the percentage of diabetes and median troponin level (p

关键词： non-obstructive myocardial infarction Cardiac Biomarkers Coronary Angiography non-ST Elevated myocardial infarction

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