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Prognostic value of the neutrophil-to-lymphocyte ratio for hepatocellular carcinoma patients with portal/hepatic vein tumor thrombosis

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World Journal of Gastroenterology 2017年第17期23卷 3122-3132页

作者： Shao-Hua Li Qiao-Xuan Wang Zhong-Yuan Yang Wu Jiang Cong Li Peng Sun Wei Wei Ming Shi Rong-Ping Guo State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer MedicineCancer Center of Sun Yat-Sen University Department of Hepatobiliary Surgery Cancer Center of Sun Yat-Sen University Department of Radiation Oncology Cancer Center of Sun Yat-Sen University Department of Head and Neck Surgery Cancer Center of Sun Yat-Sen University Department of Colorectal Surgery Cancer Center of Sun Yat-Sen University Department of Anesthesia Cancer Center of Sun YatSen University

AIM To investigate whether the preoperative neutrophil-tolymphocyte ratio(NLR) could predict the prognosis of hepatocellular carcinoma(HCC) patients with portal/hepatic vein tumor thrombosis(PVTT/HVTT) after *** The study population included 81 HCC patients who underwent hepatectomy and were diagnosed with PVTT/HVTT based on pathological examination. The demographics, laboratory analyses, and histopathology data were *** Overall survival(OS) and disease-free survival(DFS) were determined in the patients with a high(> 2.9) and low(≤ 2.9) NLR. The median OS and DFS duration in the high NLR group were significantly shorter than those in the low NLR group(OS: 6.2 mo vs 15.7 mo, respectively, P = 0.007; DFS: 2.2 mo vs 3.7 mo, respectively, P = 0.039). An NLR > 2.9 was identified as an independent predictor of a poor prognosis of OS(P = 0.034, HR = 1.866; 95%CI: 1.048-3.322) in uni-and multivariate analyses. Moreover, there was a significantly positive correlation between the NLR and the Child-Pugh score(r = 0.276, P = 0.015) and the maximum diameter of the tumor(r = 0.435, P 2.9 indicates poorer OS and DFS.

关键词： Hepatocellular 癌 Portal/hepatic 静脉肿瘤血栓 neutrophil-to-lymphocyte 比率预后

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Comments to ＂neutrophil-to-lymphocyte ratio compared to N-terminal pro- brain natriuretic peptide as a prognostic marker of adverse events in elderly patients with chronic heart failure＂

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Journal of Geriatric Cardiology 2017年第10期14卷 657-658页

作者： Kahraman Cosansu Cagin Mustafa Ureyen Department of Cardiology Sakarya Education and Research Hospital Sakarya Turkey

We have read the article which entitled "neutrophil-to-lymphocyte ratio compared to N-terminal pro-brain natriuretic peptide as a prognostic marker of adverse events in elderly patients with chronic heart failure" pub... 详细信息

关键词： Atrial 纤维性颤动 C 反应的蛋白质主要心血管的事件 neutrophil-to-lymphocyte 比率

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