检索结果-南通市图书馆

Hypothalamic GABAergic neurocircuitry in the regulation of energy homeostasis and sleep/wake control

Medical Review 2022年第5期2卷 531-540页

作者： Hong Jiang Department of Neurobiology School of Basic Medical SciencesNeuroscience Research InstitutePeking UniversityNo.38Xueyuan RoadHaidian DistrictBeijing 100083China Key Laboratory for Neuroscience Ministry of Education/National Health Commission of ChinaPeking UniversityBeijing 100083China

Gamma-aminobutyric acid(GABAergic)neuron,as one of important cell types in synaptic transmission,has been widely involved in central nervous system(CNS)regulation of organismal physiologies including cognition,emotion,arousal and ***,upon their distribution in various brain regions,effects of GABAergic neurons in the brain are very *** current report,we will present an overview of the role of GABAergic mediated inhibitory neurocircuitry in the hypothalamus,underlying mechanism of feeding and sleep homeostasis as well as the characteristics of latest transcriptome profile in order to call attention to the GABAergic system as potentially a promising pharmaceutical intervention or a deep brain stimulation target in eating and sleep disorders.

关键词： energy homeostasis feeding gamma-aminobutyric acid hypothalamus neurocircuitry sleep wakefulness.

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Diffusion Tensor Imaging and Its Application to Traumatic Brain Injury: Basic Principles and Recent Advances

引用

Open Journal of Medical Imaging 2012年第4期2卷 137-161页

作者： Ping-Hong Yeh Terrence R. Oakes Gerard Riedy National Capital Neuroimaging Consortium Walter Reed National Military Medical Center Bethesda USA National Intrepid Center of Excellence Bethesda USA Traumatic Brain Injury Image Analysis Lab Henry Jackson Foundation for the Advancement of Military Medicine Rockville USA

Traumatic axonal injury is a progressive process evoked by shear forces on the brain, gradually evolving from focal axonal alteration and cumulating in neural disconnection. Clinical classifiers and conventional neuroimaging are limited in traumatic axonal injury detection, outcome prediction, and treatment guidance. Diffusion weighted imaging is an advanced magnetic resonance imaging (MRI) technique that is sensitive to the movement of water molecules, providing additional information on the micro-structural arrangement of tissue. Quantitative analysis of diffusion metrics can aid in the localization of axonal injury and/or de(dys)myelination caused by trauma. Diffusion MRI tractography is an extension of diffusion weighted imaging, and can provide additional information about white matter pathways and the integrity of brain neural networks. Both techniques are able to detect the early micro-structural changes caused by Traumatic Brain Injury (TBI), and can be used to increase understanding of the mechanisms of brain plasticity in recovery after brain injury and possibly optimize treatment planning of patients with Traumatic Brain Injury. This review focuses on the theoretical basis and applied advanced techniques of diffusion weighted imaging, their limitations and applications, and future directions in the application to TBI.

关键词： Brain Network Connectivity High Angular Resolution Diffusion Imaging (HARDI) Diffusion Tensor Imaging (DTI) neurocircuitry Neuroimaging Traumatic Axonal Injury (TAI) Traumatic Brain Injury (TBI) Tractography White Matter

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：