检索结果-南通市图书馆

Self-assembled natural phytochemicals for synergistically antibacterial application from the enlightenment of traditional Chinese medicine combination

引用

Acta Pharmaceutica Sinica B 2020年第9期10卷 1784-1795页

作者： Xuehao Tian Penglong Wang Tong Li Xuemei Huang Wenbo Guo Yuqin Yang Mengmeng Yan Hao Zhang Desheng Cai Xiaohui Jia Feifei Li Bing Xu Tao Ma Cong Yan Haimin Lei School of Chinese Pharmacy Beijing University of Chinese MedicineBeijing 102488China School of Life Science Beijing University of Chinese MedicineBeijing 102488China

The application of nanotechnology for antimicrobial delivery has capacity to improve anti-bacterial ***,the usage of various inorganic and organic carriers,such as metal ions,nano-silicon and surfactants,might increase the potential toxicity of nanoparticles and make their clinical transformation more ***,a nano-delivery system was constructed by direct self-assembly of antibacterial phytochemicals(berberine and rhein)originated from traditional Chinese medicine Coptis chinensis *** Rheum palmatum L.,*** X-ray single crystal diffraction,nuclear magnetic resonance and other spectra characterizations,the stacked structure of nanoparticles was profoundly ***,rhein acted as the layered backbone and berberine embedded in *** vitro bacteriostasis experiment showed the minimum bactericidal concentration of nanoparticles was 0.1μmol/mL,which was lower than that of berberine and *** results of confocal laser scanning microscope,biofilm quantitive assay and scanning electron microscopy indicated that nanoparticles had strong inhibitory effects on Staphylococcus aureus *** importantly,transmission electron microscopy and mass spectra indicated the further bacteriostatic mechanism of ***,the nanoparticles had well biocompatibility and *** study will open up new prospect that the design of self-assemblies between active phytochemicals can be originated from traditional Chinese medicine combination.

关键词： natural phytochemicals Self-assembly Antibacterial Synergistic effect Staphylococcus aureus Traditional Chinese medicine

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Special issue on“molecular targets,biomarkers and animal models for anti-cancer pharmacological research:potentials and challenges from chemoprevention to chemotherapeutic treatment”

引用

Acta Pharmacologica Sinica 2007年第9期28卷 1261-1261页

作者： Ah-Ng Tony KONG Center for Cancer Prevention Research Ernest Mario School of PharmacyRutgersThe State University of New JerseyPiscatawayNew Jersey 08854USA

With the current advances in the field of cancer research particularly in cancer chemoprevention,we have much tocelebrate but we also have a lot of challenges before *** of the challenges include finding appropriate animal models forpredicting efficacy of chemopreventive compounds for human cancers,of which are usually highly complex and involvedmultiple genes in nature and translating our basic research into clinical *** of the other challenges will be todisseminate our ideas into the larger biomedical and pharmaceutical *** this in mind,I have been asked by theEditorial Team of Acta Pharmacologica Sinica to organize a special issue to discuss the current advances in cancerchemoprevention from prevention to *** distinction and the potential overlapping nature of cancer chemopreventionversus chemotherapeutic treatment has become somewhat blurred,since prevention of carcinogenesis encompasses pre-venting any or all of the three stages of carcinogenesis namely initiation,promotion and ***,many

关键词： cancer chemoprevention dietary food factors natural phytochemicals molecular targets biomarkers animal models

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：