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The impacts of national essential medicine policies on the rational use of medicines in China: A cross-sectional study in primary health care institution

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Journal of Chinese Pharmaceutical Sciences 2019年第1期28卷 49-55页

作者： Xinpu Lu Zhigang Guo Mengyuan Fu Haishaerjiang Wushouer Luwen Shi Xiaodong Guan Beijing Cancer Hospital Beijing 100142China Department of Pharmacy Peking University Hospital of StomatologyBeijing 100081China International Research Center for Medicinal Administration Peking University Health Science CenterBeijing 100191China Department of Pharmacy Administration and Clinical Pharmacy School of Pharmaceutical SciencesPeking University Health Science CenterBeijing 100191China

Irrational use of medicines is a major problem worldwide, and it is believed there would be positive correlation between the national essential medicines policies(NEMPs) and the level of rational use of medicines(RUMs). Though there is some early evidence on the NEMPs’ effects on RUMs in China, the evidence is scarce, and conclusions vary. In the present study, we aimed to evaluate the impacts of the NEMPs of China on the RUMs in the primary health care institutions(PHCs). A cross-sectional survey was conducted in 2010. A total of 201 PHCs from six provinces of China were selected, and 39 181 prescriptions were extracted from January to June, 2010. Six indicators were used and tested by independent-samples T test. We found that the average number of drugs per prescription in PHCs with NEMP implementation(the treatment group) was significantly higher than that of the group without NEMP implementation(the control group)(3.37 vs. 2.83, Pessential medicines list, the treatment group exhibited the higher ratio(76.12% vs. 53.45%, P<0.01). From this study, the NEMPs were not likely to have a positive impact on RUMs. China still needed efforts to improve the selection, the absence of physicians’ active involvement, and the patients’ habits of irrational medication use.

关键词： Rational use of medicines Primary health care institutions national essential medicines policies Health care reforms

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