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A Semantic Adversarial Network for Detection and Classification of myopic maculopathy

Computers, Materials & Continua 2023年第4期75卷 1483-1499页

作者： Qaisar Abbas Abdul Rauf Baig Ayyaz Hussain College of Computer and Information Sciences Imam Mohammad Ibn Saud Islamic University(IMSIU)Riyadh11432Saudi Arabia Department of Computer Science Quaid-i-Azam UniversityIslamabad44000Pakistan

The diagnosis of eye disease through deep learning (DL) technologyis the latest trend in the field of artificial intelligence (AI). Especially indiagnosing pathologic myopia (PM) lesions, the implementation of DL is adifficult task because of the classification complexity and definition system ofPM. However, it is possible to design an AI-based technique that can identifyPM automatically and help doctors make relevant decisions. To achieve thisobjective, it is important to have adequate resources such as a high-qualityPM image dataset and an expert team. The primary aim of this research isto design and train the DLs to automatically identify and classify PM intodifferent classes. In this article, we have developed a new class of DL models(SAN-FSL) for the segmentation and detection of PM through semanticadversarial networks (SAN) and few-short learning (FSL) methods, *** to DL methods, the conventional segmentation methodsuse supervised learning models, so they (a) require a lot of data for trainingand (b) fixed weights are used after the completion of the training *** solve such problems, the FSL technique was employed for model trainingwith few samples. The ability of FSL learning in UNet architectures is beingexplored, and to fine-tune the weights, a few new samples are being providedto the UNet. The outcomes show improvement in the detection area andclassification of PM stages. Betterment in the result is observed by sensitivity(SE) of 95%, specificity (SP) of 96%, and area under the receiver operatingcurve (AUC) of 98%, and the higher F1-score is achieved using 10-fold ***, the obtained results confirmed the superiority of theSAN-FSL method.

关键词： Artificial intelligence cardiovascular vision loss deep learning few-shot learning semantic segmentation myopic maculopathy

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Automated detection of myopic maculopathy from color fundus photographs using deep convolutional neural networks

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Eye and Vision 2024年第4期10卷 11-22页

作者： Jun Li Lilong Wang Yan Gao Qianqian Liang Lingzhi Chen Xiaolei Sun Huaqiang Yang Zhongfang Zhao Lina Meng Shuyue Xue Qing Du zhichun Zhang Chuanfeng LV Haifeng Xu Zhen Guo Guotong Xie Lixin Xie Qingdao Eye Hospital of Shandong First Medical University 5 Yanerdao RoadQingdao 266071China State Key Laboratory Cultivation Base Shandong Provincial Key Laboratory of OphthalmologyShandong Eye InstituteShandong First Medical University&Shandong Academy of Medical SciencesQingdao 266071China Ping An Healthcare Technology 9F Building BPingAn IFCNo.1-3 Xinyuan South RoadBejing 100027China Shandong Eye Hospital of Shandong First Medical University Jinan 250021China Rongcheng Eye Hospital Weihai 264200China Hospital of PLA Navy Qingdao 266071China Qilu Hospital of Shandong University(Qingdao) Qingdao 266035China Ping An Healthcare and Technology Company Limited hanghai 200030China ping An International Smart City Technology Company Limited Shenzhen 518000China.

Background:myopic maculopathy(MM)has become a major cause of visual impairment and blindness worldwide,especially in East Asian *** learning approaches such as deep convolutional neural networks(DCNN)have been successfully applied to identify some common retinal diseases and show great potential for the intelligent analysis of *** study aimed to build a reliable approach for automated detection of MM from retinal fundus images using DCNN ***:A dual-stream DCNN(DCNN-DS)model that perceives features from both original images and corresponding processed images by color histogram distribution optimization method was designed for classification of no MM,tessellated fundus(TF),and pathologic myopia(PM).A total of 36,515 gradable images from four hospitals were used for DCNN model development,and 14,986 gradable images from the other two hospitals for external *** also compared the performance of the DCNN-DS model and four ophthalmologists on 3000 randomly sampledfundus ***:The DCNN-DS model achieved sensitivities of 93.3%and 91.0%,specificities of 99.6%and 98.7%,areas under the receiver operating characteristic curves(AUCs)of 0.998 and 0.994 for detecting PM,whereas sensitivities of 98.8%and 92.8%,specificities of 95.6%and 94.1%,AUCs of 0.986 and 0.970 for detecting TF in two external testing *** the sampled testing dataset,the sensitivities of four ophthalmologists ranged from 88.3%to 95.8%and 81.1%to 89.1%,and the specificities ranged from 95.9%to 99.2%and 77.8%to 97.3%for detecting PM and TF,***,the DCNN-DS model achieved sensitivities of 90.8%and 97.9%and specificities of 99.1%and 94.0%for detecting PMand T,***:The proposed DCNN-DS approach demonstrated reliable performance with high sensitivity,specificity,and AUC to classify different MM levels on fundus photographs sourced from *** can help identify MM automatically among the large myopic groups and show great potenti

关键词： myopic maculopathy Tessellated fundus Pathologic myopia Deep convolutional neural network Color fundus image

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Review on current concepts of myopia and its control strategies

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International Journal of Ophthalmology(English edition) 2021年第4期14卷 606-615页

作者： Raju Kaiti Ranjila Shyangbo Indra Prasad Sharma Manish Dahal Nepal Eye Hospital Kathmandu 44600Nepal National Academy of Medical Sciences Kathmandu 44600Nepal Gyalyum Kesang Choeden Wangchuck National Eye Center JDW National Referral HospitalThimpu 11001Bhutan

Myopia poses a significant burden on the healthcare system,economy and quality of *** is an emerging global public health challenge and requires interventions to delay or stop onset and *** changing times and evidence,the concepts of myopia are changing along with the treatment and control *** modifications including increased outdoors time and reduced near work,optical and pharmaceutical management options are *** paper presents a current overview on the concepts of myopia,and is expected to summarize updates on myopia control methods.

关键词： atropine myopia myopia control myopic maculopathy public health

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Complications of high myopia:An update from clinical manifestations to underlying mechanisms

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Advances in Ophthalmology Practice and Research 2024年第3期4卷 156-163页

作者： Yu Du Jiaqi Meng Wenwen He Jiao Qi Yi Lu Xiangjia Zhu Eye Institute and Department of Ophthalmology Eye&ENT HospitalFudan UniversityShanghaiChina NHC Key Laboratory of Myopia and Related Eye Diseases Key Laboratory of Myopia and Related Eye DiseasesChinese Academy of Medical SciencesShanghaiChina Shanghai Key Laboratory of Visual Impairment and Restoration ShanghaiChina State Key Laboratory of Medical Neurobiology Fudan UniversityShanghaiChina

Background:High myopia is one of the major causes of visual impairment and has an ever-increasing prevalence,especially in East *** is characterized by excessive axial elongation,leading to various blinding complications that extend beyond mere refractive errors and persist immovably after refractive surgery,presenting substantial public health *** text:High myopia-related complications include lens pathologies,atrophic and tractional maculopathy,choroidal neovascularization,peripheral retinal degenerations and retinal detachment,and glaucoma and heightened susceptibility to intraocular pressure(IOP)*** lens changes characteristic of high myopia include early cataractogenesis,overgrowth of lens,weakened zonules,and postoperative capsular contraction syndrome,possibly driven by inflammatory pathogenesis,***-shaped macula and cilioretinal arteries are two newly identified protective factors for central vision of highly myopic *** patients also face risks of open-angle glaucoma and IOP spike following intraocular *** alternations of optic nerve in high myopia can complicate early glaucoma detection,necessitating comprehensive examinations and close ***,thinner trabecular meshwork increases this risk;conversely lamina cribrosa defects may offer a fluid outlet,potentially mitigating the ***,anxiety has emerged as the first recognized extra-ocular complication in high myopia,with an underlying inflammatory pathogenesis that connects visual stimulus,blood and ***:High myopia induces multiple ocular and potential mental health complications,underscoring the need to develop more effective strategies to improve both physical and emotional well-being of these patients,among which anti-inflammation might possibly represent a promising new target.

关键词： High myopia Cataract myopic maculopathy Open-angle glaucoma Anxiety

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Pathologic myopia

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Annals of Eye Science 2018年第1期3卷 58-68页

作者： Kyoko Ohno-Matsui Department of Ophthalmology and Visual Science Tokyo Medical and Dental UniversityTokyoJapan

Pathologic myopia is the major cause of the loss of the best-corrected visual acuity(BCVA)worldwide,especially in East Asian *** loss of BCVA is caused by the development of myopic macula patchy,myopic traction macula patchy,and myopic optic neuropathy(or glaucoma).The development of such vision-threatening complications is caused by eye deformity,characterized by a formation of posterior *** recent advance in ocular imaging has greatly facilitated the clarification of pathologies and pathogenesis of pathological myopia and myopia-related *** technologies include ultra-wide field fundus imaging,swept-source optical coherence tomography,and 3D *** addition,the new treatments such as anti-VEGF therapies for myopic choroid all neovascularization have improved the outcome of the ***-source OCT showed that some of the lesions of myopic maculopathy were not simply chorioretinal atrophy but were Bruch’s membrane *** of myopic traction maculopathy have been analyzed extensively by using *** understanding the pathophysiology of complications of pathologic myopia is considered useful for better management of this blinding eye disease.

关键词： Pathologic myopia(PM) posterior staphyloma myopic maculopathy myopic traction maculopathy(MTM)

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