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International Journal of Ophthalmology(English edition) 2022年第6期15卷 975-982页

作者： Yao Huang Yue Qi Wen-Bin Wei An-Li Duan Beijing Tongren Eye Center Beijing Tongren HospitalCapital Medical UniversityBeijing 100730China

AIM: To report the long-term outcome of posterior scleral reinforcement(PSR) followed by vitrectomy for pathologic myopic foveoschisis(MF).METHODS: The records of 27 patients(44 eyes) treated with posterior scleral reinforcement(PSR) followed by vitrectomy for pathologic MF were retrospectively *** best-corrected visual acuity(BCVA), refractive error, axial length, and spectral-domain optical coherence tomography findings and complications were ***: Forty-four eyes of 27 patients were included in this study. The follow-up period was 47.98±18.23mo(24-83mo). The mean preoperative BCVA(logMAR) was 1.13±0.63, and the mean postoperative BCVA was 0.30±0.33at the last visit. There showed a significant improvement in BCVA postoperatively(Pfoveoschisis. The preoperative foveal thickness was 610.45±217.11 μm and the postoperative foveal thickness at the last visit was significantly reduced to 177.64±55.40 μm(Pfoveoschisis or occurrence of full-thickness macular hole during the whole follow-up ***: For pathologic MF, PSR followed by vitrectomy is an effective procedure to improve the visual acuity and the anatomical structure of macula. It can also stabilize the axial length for a long time.

关键词： myopic foveoschisis posterior scleral reinforcement vitrectomy

Internal limiting membrane peeling combined with silicone oil or air tamponade for highly myopic foveoschisis

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International Journal of Ophthalmology(English edition) 2024年第6期17卷 1079-1085页

作者： Jin Deng Wen-Tao Sun Ke Gong Li-Ping Wang Feng-Zhi Li Xi’an People’s Hospital(Xi’an Fourth Hospital) Shaanxi Eye HospitalAffiliated People’s Hospital of Northwest UniversityXi’an 70004Shaanxi ProvinceChina

AIM:To compare the efficacy of pars plana vitrectomy(PPV)combined with internal limiting membrane(ILM)and silicone oil or sterile air tamponade for the treatment of myopic foveoschisis(MF)in highly myopic ***:This retrospective study included 48 myopic eyes of 40 patients with MF and axial lengths(ALs)ranging from 26-32 mm treated between January 2020 and January *** patients were underwent PPV combined with ILM peeling followed by sterile air or silicone oil tamponade and followed up at least *** on the features on spectral-domain optical coherence tomography(SD-OCT),the eyes were divided into the MF-only group(Group A,n=15 eyes),MF with central foveal detachment group(Group B,n=20 eyes),and MF with lamellar macular hole group(Group C,n=13 eyes).According to AL,eyes were further divided into three groups:Group D(26.01-28.00 mm,n=12 eyes),Group E(28.01-30.00 mm,n=26 eyes),and Group F(30.01-32.00 mm,n=10 eyes).The best-corrected visual acuity(BCVA),central foveal thickness(CFT),and complications were ***:The patients included 16 males and 24 females with the mean age of 56±*** BCVA and CFT improved in all groups after surgery(P0.05).The intergroup differences of BCVA and CFT postoperatively were statistically significant in Group D,E,and *** eyes were injected with sterile air,and 28 eyes were injected with silicone oil for tamponade based on the ***,there was no statistically significant difference among Groups D,E,and F in terms of the results of sterile air or silicone oil *** mean recovery time was 5.9mo for MF patients subjected to silicone oil tamponade and 7.7mo for patients subjected to sterile air tamponade,and the difference was not statistically ***:PPV and ILM peeling combined with silicone oil or sterile air tamponade can achieve good results for MF in highly myopic eyes with ALs

关键词： axial length myopic foveoschisis highly myopic internal limiting membrane pars plana vitrectomy

Long-term follow-up of vitrectomy in patients with pathologic myopic foveoschisis

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International Journal of Ophthalmology(English edition) 2017年第2期10卷 277-284页

作者： Ting Zhang Ying Zhu Chun-Hui Jiang Ge-Zhi Xu Department of Ophthalmology and Visual Science EyeEarNoseand Throat HospitalShanghai Medical SchoolFudan University Department of Ophthalmology Xiangya HospitalCentral South University Shanghai Key Laboratory of Visual Impairment and Restoration Fudan University

AIM： To report the long-term surgical outcomes of pathologic myopic foveoschisis（MF） following ***： We performed a retrospective case series analysis of 50 consecutive patients diagnosed with MF who experienced vision loss due to progression of *** 50 patients（67 eyes） were treated in our hospital with vitrectomy with internal limiting membrane（ILM） peeling from December 2004 to September *** corrected visual acuity（BCVA）,refractive error,optical coherence tomography（OCT）,and routine examination results were *** changes of BCVA,foveal anatomical features on OCT scan,and complications were the main outcome ***： The mean follow-up duration was 42±17mo（range 24 to 93mo）.BCVA improved significantly postoperatively（0.76±0.65 logM AR） compared with preoperative baselines（1.31±0.78 log MAR,P〈0.0001）,and in 53 eyes（79%） including 3 lines gain in 44 eyes（66%） at the last follow-up *** scans showed that central retinal thickness decreased from 580.0±270.0 μm preoperatively（n=67） to 179.7±84.7 μm postoperatively（n=58,P〈0.0001）.Total resolution of foveoschisis occurred in 41 eyes（61%）.Preoperative BCVA correlated well with postoperative BCVA,whereas other factors such as age,axial length,and refractive error were not *** most common complications were cataract and full-thickness macular hole formation in 14 and 9 cases,***： Patients with progressive vision loss due to MF who were treated with vitrectomy with ILM peelingshow favourable *** most eyes,visual acuity and foveal structure remain stable during long-term observation.

关键词： pathologic myopia myopic foveoschisis vitrectomy internal limiting membrane peeling

Posterior scleral reinforcement combined with vitrectomy for myopic foveoschisis

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International Journal of Ophthalmology(English edition) 2016年第2期9卷 258-261页

作者： Xiu-Juan Li Xiao-Peng Yang Qiu-Ming Li Yu-Ying Wang Jing Wang Xiao-Bei Lyu Heng Jia Department of Ophthalmology the First Affiliated Hospital of Zhengzhou University Department of Medical Equipment the First Affiliated Hospital of Zhengzhou University

AIM： To investigate the effects of posterior scleral reinforcement （PSR） combined with vitrectomy for myopic foveoschisis. ~ METHODS： Thirty-nine highly myopic eyes of 39 patients with myopic foveoschisis underwent PSR combined with vitrectomy. Best corrected visual acuity （BCVA）, refraction error, and the foveal thickness by optical coherence tomography （OCT） were recorded before and after the surgery, and complications were noted. RESULTS： The follow-up period was 12mo, and the main focus was on the results of the 12-month follow-up visit. The mean preoperative BCVA was 0.96±0.43 IogMAR. At the final follow-up visit, the mean BCVA was 0.46± 0.28 IogMAR, which significantly improved compared with the preoperative one （P =0.003）. The BCVA improved in 33 eyes （84.62%）, and unchanged in 6 eyes （15.38%）. At the end of follow-up, the mean refractive error was -15.13 ±2.55 D, and the improvement was significantly compared with the preoperative one （-17.53±4.51 D）（P= 0.002）. Twelve months after surgery, OCT showed complete resolution of the myopic foveoschisis and a reattachment of the fovea in 37 eyes （94.87%） and partial resolution in the remained two eyes （5.13%）. The foveal thickness was obviously reduced at 12-month follow-up visit （196.45±36.35um） compared with the preoperative one （389,32±75.56um）（P=0.002）. There were no serious complications during the 12mo follow-up period. CONCLUSION： PSR combined with vitrectomy is a safe and effective procedure for myopic foveoschisis with both visual and anatomic improvement.

关键词： high myopia myopic foveoschisis posteriorscleral reinforcement vitrectomy

Treatment of myopic foveoschisis via macular buckling and vitrectomy

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International Journal of Ophthalmology(English edition) 2017年第5期10卷 815-818页

作者： Si-Qi Xiong Hai-Bo Jiang Fang-Ling Li Yan-Xiu Li Jie Yang Xiao-Bo Xia Hui-Zhuo Xu Department of Ophthalmology Xiangya Hospital Central South University Changsha 410008 Hunan Province China

The aim of the present study was to evaluate the efficacy and safety of the treatment of myopic foveoschisis patients using the macular buckling with L-shaped titanium plate and silicon sponge combined with vitrectomy. The data of the patients who underwent macular buckling combined with vitrectomy was collected. The study recorded the following parameters：best corrected visual acuity（BCVA）, axial length, intraocular pressure, central macular thickness, and the position of the titanium plate. Following the surgery, the BCVA of the included patients were improved, whereas the axial lengths were reduced followed by resolution of the foveoschisis compared with that noted prior to the operations. All patients had orbital CT examination and the results indicated that the titanium plates were appropriately placed and were not in contact with the optic nerve. Therefore, it is effective to treat myopic foveaschisis by macular buckling using the L-shaped titanium plate and silicon sponge in the presence of vitrectomy.

关键词： myopic foveoschisis macular buckling vitrectomy

Long-term outcome of highly myopic foveoschisis treated by vitrectomy with or without gas tamponade

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International Journal of Ophthalmology(English edition) 2017年第9期10卷 1392-1395页

作者： Li-Na Yun Yi-Qiao Xing Department of Ophthalmology Renmin Hospital of Wuhan UniversityWuhan 430060Hubei ProvinceChina

AIM：To evaluate the long-term safety and efficacy of vitrectomy and internal limiting membrane（ILM）peeling with or without gas tamponade for highly myopic ***：We performed an open-label,observerblinded clinical trial of 85 patients with myopic foveoschisis between 2000 and *** were randomly allocated to one of two groups,those who received vitrectomy and ILM peeling without gas tamponade（no-gas group）or those who with gas tamponade（gas group）and follow up at least ***：Visual acuity of gas group improved from0.82±0.33 to 0.79±0.73 in 6mo,improved to 0.71±0.67 in 1y and within this range in the following *** acuity of no-gas group improved from 0.81±0.46 to 0.78±0.66 in 6mo,improved to 0.70±0.65 in *** finial visual acuity of two groups were significantly increased compared with the baseline（P〈0.05）.The visual acuity was improved in 35 of40 eyes（87.5%）in gas group and 29 of 33 eyes（87.9%）in no-gas group,while there were no significant differences between gas group and no-gas group in the visual *** foveoschisis on optical coherence tomography（OCT）completely resolved in 5 of 40 eyes in 1mo,14 eyes in 6mo and 40 eyes in 1y in the gas *** the foveoschisis completely resolved in 4 of 33 eyes in 1mo,10 eyes in 6mo and 33 eyes in 1y in the no-gas ***：Vitrectomy and ILM peeling without gas tamponade appears to be as effective in the treatment of myopic foveoschisis as vitrectomy and ILM with gas ***,eyes treated with no-gas tamponade showed more rapid resolution of myopic foveoschisis.

关键词： myopic foveoschisis vitrectomy internal lim-iting membrane peeling gas tamponade

Vitrectomy with residual internal limiting membrane covering and autologous blood for a secondary macular hole:A case report

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World Journal of Clinical Cases 2022年第2期10卷 671-676页

作者： Huang-Fang Ying Shuang-Qing Wu Wei-Ping Hu Li-Yang Ni Zi-Long Zhang Yong-Gen Xu Department of Ophthalmology Affiliated Hospital of Shaoxing UniversityShaoxing 312000Zhejiang ProvinceChina Department of Ophthalmology Zhejiang Provincial Integrated Chinese and Western Medicine HospitalHangzhou 310003Zhejiang ProvinceChina

BACKGROUND myopic foveoschisis(MF)is a common complication of pathological myopia.A macular hole(MH)usually results from the natural progression of MF and is a common complication of *** combined with residual internal limiting membrane(ILM)covering and autologous blood was effective for closing a secondary *** SUMMARY A 52-year-old woman presented to our clinic with a complaint of blurred vision in the right eye for 7 *** best corrected visual acuity(BCVA)was 20/100,axial length was 25.79 mm and standard equivalent refractive error was-10.5 *** optical coherence tomography revealed foveoschisis in the right *** with fovea-sparing ILM peeling was *** MH developed and gradually expanded 5 mo after the initial *** with residual ILM covering and autologous blood was *** MH closed 3 wk after the second *** Fovea-sparing ILM peeling can provide residual ILM for the treatment of MH secondary to vitrectomy for *** combined with residual ILM covering and autologous blood is effective for closing secondary MH and improving BCVA.

关键词： Vitrectomy Internal limiting membrane Autologous blood Macular hole myopic foveoschisis Case report

Resolving myopic Foveoretinal Detachment by Fovea-Saving Internal Limiting Membrane Peeling: A Case-Series Report

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Open Journal of Ophthalmology 2023年第1期13卷 106-121页

作者： Miguel Angel Quiroz-Reyes Erick Andres Quiroz-Gonzalez Miguel Angel Quiroz-Gonzalez Virgilio Lima-Gomez Oftalmologia Integral ABC Retina Department Medical and Surgical Assistance Institution (Nonprofit Organization) Affiliated with the Postgraduate Studies Division at the National Autonomous University of Mexico Mexico City Mexico Juarez Hospital Public Assistance Institution (Nonprofit Organization) Mexico City Mexico

Background: In highly myopic eyes, myopic foveoschisis (MF), the earliest stage of myopic traction maculopathy (MTM), is present in up to 34% of patients with pathologic myopia and slowly progresses to form foveoretinal detachment (FRD) or macular hole (MH) with or without macular hole retinal detachment (MHRD) as a part of its natural history. Aim: To describe the microstructural and functional results in three highly myopic eyes that underwent macular surgery for early-stage MTM. The last postoperative structural findings were correlated with the final vision and macular automated microperimetry evaluation. Methods: We retrospectively reviewed three highly myopic eyes that underwent successful fovea-saving internal limiting membrane (FS-ILM) macular surgery for chronic FRD at Oftalmologia Integral ABC, Mexico City, Mexico. We performed postoperative multimodal microstructural and functional evaluations, including SD-OCT, SS-OCT, and microperimetric macular examinations. Results: There was a substantial difference between best-corrected visual acuity (BCVA) preoperatively and postoperatively in all three cases. Postoperative surgery was associated with significant improvement in visual acuity confirmed using a paired-sample permutation test. The mean presurgical BCVA value (LogMAR;mean ± SE) was ~0.83 ± 0.15, and the postsurgical value was ~0.43 ± 0.52 (P = 0.00065). The myopic foveoretinal detachment evaluation was ~7.3 ± 3.5 months, with a mean postoperative follow-up time of ~14 ± 4.08 months. Furthermore, postoperative multimodal imaging tests demonstrated an abnormal microstructural foveal SS-OCT pattern without evidence of macular hole (MH) development at the postoperative follow-up. Macular microperimetry confirmed a subclinical reduced macula threshold sensitivity with an anomalous retinal sensitivity analysis map and a stable central foveal fixation site. Conclusions: Even with the successful microstructural disappearance of myopic macular detachment, the

关键词： Automated Microperimetry myopic Foveoretinal Detachment myopic foveoschisis myopic Macular Hole myopic Traction Maculopathy Posterior Staphyloma

Long-Term Postoperative Perfusion Indices in Surgically Resolved myopic Traction Maculopathy

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Open Journal of Ophthalmology 2023年第1期13卷 143-171页

作者： Miguel A. Quiroz-Reyes Erick A. Quiroz-Gonzalez Miguel A. Quiroz-Gonzalez Virgilio Lima-Gomez Oftalmologia Integral ABC Retina Specialists Unit Medical and Surgical Assistance Institution (Nonprofit Organization) Affiliated with the Postgraduate Studies Division at the National Autonomous University of Mexico Mexico City Mexico Institute of Ophthalmology Fundacion Conde de Valenciana Private Assistance Institution (Nonprofit Organization) Mexico City Mexico Juarez Hospital Public Assistance Institution (Nonprofit Organization) Mexico City Mexico

Background: Pathological myopia can be complicated by the presence of posterior staphyloma, macular atrophy, ruptures in Bruch’s membrane, pathologic choroidal neovascularization, and different degrees of myopic traction maculopathy. Purpose: To report the structural, functional and perfusional outcomes in patients underwent surgery for different stages of myopic traction maculopathy (MTM). Methods: A retrospective, consecutive, comparative, interventional, one-surgeon, case-control study was conducted in 46 eyes of 34 individuals between April 2015 and May 2021. Participants included normal emmetropic eyes (Control emmetropia, n = 25), healthy myopic eyes (Control high myopia, n = 20), and operated and structurally fully resolved myopic eyes with different stages of MTM (Surgically treated group, n = 46). Long-term postoperative functional and perfusional follow-up evaluations were performed with spectral domain-optical coherence tomography (SD-OCT) and OCT angiography. The primary outcome measure included long-term functional, structural and perfusion macular status across groups. Results: Forty-six eyes in 34 patients were included in the study group, with both eyes affected in 12 (26.3%) patients. The mean axial length was 29.89 ± 1.67 mm. The preoperative logMAR was 1.29 ± 0.54 and the postoperative logMAR was 0.60 ± 0.52 (P Conclusion: Compared to emmetropic and healthy myopic eyes, surgically-resolved MTM eyes generally have larger superficial foveal avascular zone area, lower vessel density, smaller choriocapillaris flow area, thinner central subfoveal thickness, and more macular defects. Eyes with stage III or IV MTM had larger deviation compared to eyes at earlier stages. Visual function change after surgery was associated with superficial foveal avascular zone area. Better functional, structural and perfusion index outcomes were observed when highly myopic eyes underwent early surgery.

关键词： Choriocapillaris Flow Area Deep Vascular Plexus Foveoretinal Detachment myopic foveoschisis Foveal Avascular Zone myopic Macular Hole