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Observations from the Working Group Peritoneal Carcinosis

Journal of Cancer therapy 2022年第8期13卷 507-524页

作者： Manju Domnick Martin Domnick Iris Ernst Frank P. Müller Viktor Rempel Norman Bitterlich Hüseyin Sahinbas Stefan Könemann Stathis Philippou Praxis and Praxisklinik Domnick Herten Germany German Centre for Stereotaxy and Precision Radiation (DZSP) Soest Germany Catholic Karl Leisner Clinic gGmbH Kleve Germany St. Anna Hospital Herne Herne Germany Medizin & Service GmbH Chemnitz Germany Praxis für Hyperthermie Düsseldorf Germany Radiotherapy Centre Bochum Bochum Germany Institute of Pathology of the Augusta Hospital Bochun Germany

The aim of this report was to describe the feasibility, overall survival and quality of life of combining multimodal therapy with a complementary therapy concept called LOTUS Care Cure program. The peritoneal carcinomatosis (PC) working group described their observations on the combination of multimodal therapy with a complementary therapy concept based on 132 patients with different cancer entities with suspected PC. PC was not confirmed by laparoscopy in 32.5% of the patients included in the working group of patients with suspected PC. Patient compliance and the feasibility were high. For Ki67, there is a cut-off at 45% with a slower progression at 45%. The higher the Karnofsky index, the more improved the therapy and tolerability, with a cut-off of 80%. Overall, 72.0% of patients died. The median survival time in the overall population was 3.74 years (95% CI, 2.57 to 4.91) with a sharp decline in the first 16 weeks. The quality of life of patients can be improved with the implementation of the complementary LOTUS Care Cure Project. Overall, the therapy of PC requires a multi-professional team of therapists and a multimodal therapy concept. The multimodal concept together with the Lotus Care Cure project shows very good feasibility with high compliance and ultimately leads to better and low-risk patient care.

关键词： multimodal and complementary therapy Peritoneal Carcinosis Quality of Life

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