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Pancreatic transplant surgery and stem cell therapy:Finding the balance between therapeutic advances and ethical principles

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World Journal of Stem Cells 2022年第8期14卷 577-586页

作者： Martina Padovano Matteo Scopetti Federico Manetti Donato Morena Davide Radaelli Stefano D’Errico Nicola Di Fazio Paola Frati Vittorio Fineschi Department of Anatomical HistologicalForensic and Orthopaedic SciencesSapienza University of RomeRome 00185Italy Department of Medical Surgical Sciences and Translational Medicine Sapienza University of RomeRome 00189Italy Department of Medicine Surgery and HealthUniversity of TriesteTrieste 34149Italy

The latest achievements in the field of pancreas transplantation and stem cell therapy require an effort by the scientific community to clarify the ethical implications of pioneering treatments,often characterized by high complexity from a surgical point of view,due to transplantation of multiple organs at the same time or at different times,and from an immunological point of view for stem cell *** fundamental value in the field of organ transplants is,of course,a solidarity principle,namely that of protecting the health and life of people for whom transplantation is a condition of functional recovery,or even of *** nature of this value is that of a concept to which the legal discipline of transplants entrusts its own ethical dignity and for which it has ensured a constitutional recognition in different *** general principle of respect for human life,both of the donor and of the recipient,evokes the need not to put oneself and one’s neighbor in dangerous *** present ethical reflection aims to find a balance between the latest therapeutic advances and several concepts including the idea of the person,the respect due to the dead,the voluntary nature of the donation and the consent to the same,the gratuitousness of the donation,the scientific progress and the development of surgical techniques,and the policies of health promotion.

关键词： Pancreas transplantation multi-organ transplants Stem cell therapy Ethical principles Donor Recipient

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