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Disparities in 36 cancers across 185 countries: secondary analysis of global cancer statistics

Frontiers of Medicine 2024年第5期18卷 911-920页

作者： Qianru Li Changfa Xia He Li Xinxin Yan Fan Yang Mengdi Cao Shaoli Zhang Yi Teng Siyi He Maomao Cao Wanqing Chen Office of Cancer Screening National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China

Cancer is a major public health problem and represents substantial disparities *** study reported estimates for 36 cancers across 185 countries by incidence,mortality,5-year prevalence,mortality-toprevalence ratio(MPR),and mortality-to-incidence ratio(MIR)to examine its association with human development index(HDI)and gross national income(GNI).Data were collected from the GLOBOCAN *** and MIR were calculated by sex,age group,country,and cancer type and then summarized into ***’s population and global cancer spectrum were used to calculate age-and type-standardized *** analyses were conducted to assess *** showed that breast cancer was the most diagnosed cancer ***-and middle-income countries had high MPR and *** of esophagus,pancreas,and liver had the highest *** and the older population had the highest *** and GNI were positively correlated with incidence and mortality but negatively correlated with MPR/*** disparities in cancer burden were observed among 36 cancer types across 185 *** development may contribute to narrowing these disparities,and tailored strategies are crucial for regional-and country-specific cancer control.

关键词： cancer burden mortality-to-prevalence ratio mortality-to-incidence ratio disparities global

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Changes of human immunodeficiency virus (HIV) burden globally and in China over three decades: a secondary analysis of global HIV statistics

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Chinese Medical Journal 2022年第22期135卷 2690-2698页

作者： Yanqiu Lu Shengquan Tang Yuanyuan Qin Vijay Harypursat Hao Wu Yaokai Chen Department of Infectious Diseases Chongqing Public Health Medical CenterChongqing 400036China Beijing Key Laboratory for HIV/AIDS Research Clinical and Research Center for Infectious DiseasesBeijing Youan HospitalCapital Medical UniversityBeijing 100069China

Background: A more comprehensive understanding of the trends of incidence, prevalence, and mortality in human immunodeficiency virus (HIV), and their complex interrelationships, may provide important evidence for decision-making related to HIV prevention and control. The variances in these indices between different population groups, genders, and ages are critical to decipher evolving patterns of the HIV epidemic in specific ***: A secondary analysis of relevant data was conducted using data extracted from the Global Burden of Disease study of 2019. HIV/acquired immune deficiency syndrome (AIDS) incidence, prevalence, AIDS-related mortality, and mortality-to-prevalence ratio (MPR) for annual percentage change, average annual percentage change (AAPC), and corresponding 95% confidence intervals (CIs) were calculated using joinpoint regression statistical ***: The AAPC of HIV/AIDS incidence, prevalence, AIDS-related mortality rate, and MPR were -1.4 (95% CI: -1.6, -1.2), 4.1 (95% CI: 4.0, 4.3), 2.0 (95% CI: 1.7, 2.3), and -2.1 (95% CI: -2.3, -1.8) between 1990 and 2019 globally, and were 3.5 (95% CI: 2.2, 4.8), 6.9 (95% CI: 6.8, 7.0), 8.1 (95% CI: 7.1, 9.1), and 1.2 (95% CI: 0.1, 2.3) in China during the same period. In terms of differences in the preceding indicators by gender, we observed a similar pattern of trends for male and female genders both globally and in China during the entire study period. Each specific age group exhibits a distinct pattern in terms of incidence, prevalence, mortality rate, and MPR both globally and in ***: prevalence and mortality rates of HIV/AIDS have increased between 1990 and 2019 globally and in China. While the incidence rate and MPR have declined globally over the past three decades, these two indicators are observed to present an increasing trend in China. There is a high HIV burden among young and middle-aged adults globally;however, the elderly have a high HIV burden in China. HIV scre

关键词： Human immunodeficiency virus Incidence mortality mortality-to-prevalence ratio prevalence

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