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检索条件"主题词=Monoamine oxidase B"
4 条 记 录,以下是1-10 订阅
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8-Hydroxyquinolylnitrones as multifunctional ligands for the therapy of neurodegenerative diseases
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Acta Pharmaceutica Sinica b 2023年 第5期13卷 2152-2175页
作者: Damijan Knez Daniel Diez-Iriepa Mourad Chioua Andrea Gottinger Milica Denic Fabien Chantegreil Florian Nachon Xavier brazzolotto Anna Skrzypczak-Wiercioch Ane Meden Anja Pilar Janko Kos Simon akelj Jure Stojan Kinga Saat Julia Serrano Ana Patricia Fernández Aitana Sánchez-García Ricardo Martínez-Murillo Claudia binda Francisco López-Muoz Stanislav Gobec JoséMarco-Contelles University of Ljubljana Faculty of PharmacyLjubljana 1000Slovenia Laboratory of Medicinal Chemistry(Institute of Organic Chemistry CSIC)Madrid 28006Spain Departamento de Química Orgánicay Química Inorgánica Alcaláde HenaresMadrid 28871Spain Department of biology and biotechnology University of PaviaPavia 27100Italy Département de Toxicologie et Risques Chimiques Institut de Recherche Biomédicale des ArméesParis 91220France Department of Animal Anatomy and Preclinical Sciences University Centre of Veterinary Medicine JU-UAUniversity of Agriculture in KrakowKrakow 30-059Poland Institute of biochemistry Faculty of MedicineUniversity of LjubljanaLjubljana 1000Slovenia Department of Pharmacodynamics Chair of PharmacodynamicsFaculty of PharmacyJagiellonian University Medical CollegeKrakow 30-688Poland Department of Translational Neurobiology Neurovascular Research GroupCajal Institute(CSIC)Madrid 28002Spain biotechnology and Vegetal biology Department Escuela Técnica Superior de Ingeniería AgronómicaAlimentaria y de BiosistemasUniversidad Politécnica de MadridMadrid 28040Spain Faculty of Health Camilo JoséCela University of Madrid(UCJC)Neuropsychopharmacology Unit“Hospital 12 de Octubre”Research InstituteMadrid 28692Spain
We describe the development of quinolylnitrones(QNs)as multifunctional ligands inhibiting cholinesterases(ChEs:acetylcholinesterase and butyrylcholinesterase—h bChE)and monoamine oxidases(hMAO-A/b)for the therapy of ... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
No synergism between bis(propyl)-cognitin and rasagiline on protecting dopaminergic neurons in Parkinson's disease mice
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Neural Regeneration Research 2016年 第8期11卷 1339-1346页
作者: Cheng-you Zheng bao-jian Guo Wei Cai Wei Cui Shing-hung Mak Yu-qiang Wang Simon Ming-yuen Lee Yi-fan Han Zai-jun Zhang Institute of New Drug Research and Guangzhou Key Laboratory of Innovative Chemical Drug Research in Cardiocerebrovascular Diseases Jinan University College of Pharmacy School of Medicine Ningbo University Department of Applied biology and Chemical Technology Institute of Modern Chinese MedicineThe Hong Kong Polytechnic University State Key Laboratory of Quality Research of Chinese Medicine and Institute of Chinese Medical Sciences University of Macao
Rasagiline,a monoamine oxidase-b inhibitor,and bis(propyl)-cognitin(b3C),a novel dimer are reported to be neuroprotective.Herein,the synergistical neuroprotection produced by rasagiline and b3 C was investigated i... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
Promising drug targets and associated therapeutic interventions in Parkinson's disease
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Neural Regeneration Research 2021年 第9期16卷 1730-1739页
作者: Sachchida Nand Rai Payal Singh Ritu Varshney Vivek K.Chaturvedi Emanuel Vamanu M.P.Singh brijesh Kumar Singh Centre of biotechnology University of AllahabadPrayagrajIndia Department of Zoology Institute of ScienceBanaras Hindu UniversityVaranasiIndia Department of bioengineering and Chemistry Indian Institute of Technology GandhinagarPalajGujaratIndia Faculty of biotechnology University of Agronomic Science and Veterinary MedicineBucharestRomania Department of Pathology and Cell biology Columbia University Medical CenterNew YorkNYUSA
Parkinson's disease(PD) is one of the most debilitating brain diseases. Despite the availability of symptomatic treatments, response towards the health of PD patients remains scarce. To fulfil the medical needs of the... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
Zhichan powder regulates nigrostriatal dopamine synthesis and metabolism in Parkinson's disease rats
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Neural Regeneration Research 2012年 第27期7卷 2107-2114页
作者: Qingwei Zhou Jiajun Chen Shihong Yi Yongwei Lou Weimin Tang Yongmao Liu Pengguo Zhang Department of biochemistry and Molecular biology Institute of Regenerative Medical Sciences Jilin University Changchun 130021 JilinProvince China Department of Neurology China-Japan Union Hospital of Jilin University Changchun 130013 Jflin Province China Department of Immunology Norman Bethune College of Medicine Jilin University Changchun 130021 Jilin Province China Department of Clinical Laboratory Changchun Municipal People's Hospital Changchun 130041 Jilin Province China Department of Radiology Second Clinical Hospital of Jilin University Changchun 130021 Jilin Province China
In this study, rat models of Parkinson's disease induced by substantia nigra injection of 6-hydroxy-dopamine were intragastrically administered Zhichan powder daily for 50 days. Reverse transcription PCR results show... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论