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Diagnosis of intraductal papillary mucinous neoplasm using endoscopic ultrasound guided microbiopsies:A case report

World Journal of Gastrointestinal Endoscopy 2018年第7期10卷 125-129页

作者： Charlotte Vestrup Rift Bojan Kovacevic John Gásdal Karstensen Julie Plougmann Pia Klausen Anders Toxvaerd Evangelos Kalaitzakis Carsten Palnaes Hansen Jane Preuss Hasselby Peter Vilmann Department of Pathology Copenhagen University Hospital RigshospitaletCopenhagen 2100Denmark Gastro Unit Division of EndoscopyCopenhagen University Hospital Herlev and GentofteHerlev 2730Denmark Gastro Unit Division of SurgeryCopenhagen University HospitalHvidovre2650 HvidovreDenmark Department of Pathology Copenhagen University Hospital Herlev and GentofteHerlev 2730Denmark Department of Gastrointestinal surgery Copenhagen University Hospital RigshospitaletCopenhagen 2100Denmark

Pancreatic cysts are increasingly diagnosed due to expanding use of cross-sectional imaging,but current diagnostic modalities have limited diagnostic accuracy.Recently,a novel through-the-needle microbiopsy forceps has become available,offering the possibility of obtaining cyst-wall biopsies.We present a case of 41-year-old male with chronic pancreatitis and a 2-cm pancreatic cyst,initially considered a pseudocyst.Subsequently,endoscopic ultrasou-nd guided microbiopsies were successfully obtained,which surprisingly revealed an intraductal papillary mucinous neoplasm of mixed subtype with low grade dysplasia.In conclusion,obtaining biopsies from the wall of the pancreatic cystic lesions with this novel instrument is feasible and,as demonstrated in this case,can possibly alter the clinical outcome.Microbiopsies offered enough cellular material,allowing supplemental gene mutation analysis,which combined with other modalities could lead to a more individual approach when treating pancreatic cysts.However,prospective studies are warranted before routine clinical implementation.

关键词： microbiopsy Pancreatic cyst Endoscopic ultrasound-fine needle aspiration Intraductal papillary mucinous neoplasm Chronic pancreatitis

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Male Breast Nodules in Ouagadougou (Burkina Faso): Radiological and Histopathological Aspects

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Open Journal of Radiology 2018年第4期8卷 274-280页

作者： Nina-Astrid Nde Ouedraogo Madina Napon Bénilde Ma Kambou Tiemtore Boubakar Ouattara Abel Bamouni Ousséini Diallo Claudine Lougue Sorgho Rabiou Cisse Service of Radiology of the Hospital of Bogodogo District Ouagadougou Burkina Faso Service of Radiology of the Pediatric Teaching Hospital Charles de Gaulle Ouagadougou Burkina Faso Service of Radiology of the Teaching Hospital Yalgado Ouédraogo Ouagadougou Burkina Faso

Objective: To describe the radiological and histological aspects of breast nodules among men in our practice setting. Methodology: This is a descriptive and retrospective study conducted from January 2014 to October 2017. The study included male patients with breast nodules classified ACR3, 4 or 5 after a mammographic and ultrasound scan. These lesions were explored through an ultrasound-guided breast microbiopsy. The following are the variables collected: age, family history of breast cancer, medical history, ACR classification, nodule size, and anatomopathologic diagnosis. Results: 13 breast nodules were explored among 13 male subjects. Mammography and breast ultrasound enabled to identify one ACR3 lesion, 10 ACR4 lesions and 2 ACR5 lesions. The average age was 56.53 ± 14.63 years and the average size of the nodules 28.91 ± 13.62 mm. As for histology, there were seven malignant tumors and six benign tumors. The average age of patients with malignancy was 61.45 ± 13.62 years. The malignant nodules average size was 29.45 ± 12.54 mm. Malignant tumors exclusively consisted of invasive breast carcinomas while Benign ones consisted of dystrophic and inflammatory lesions. Conclusion: Most often Breast lesions among men had an indeterminate appearance on imaging and were predominantly malignant in histopathology.

关键词： Breast microbiopsy Cancer Breast Male Benign Nodule

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Radio-Histopathological Aspects of Breast Nodules in a Sub-Saharan African City (Ouagadougou, Burkina Faso)

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Open Journal of Medical Imaging 2018年第3期8卷 89-96页

作者： Nina-Astrid Nde Ouedraogo Bénilde Ma Kambou Tiemtore Yobi Alexis Sawadogo Boubakar Ouattara Prosper David Lamien Madina Napon Ousséini Diallo Abel Bamouni Claudine Lougue Sorgho Rabiou Cisse Radiology Department of Charles de Gaulle Teaching Paediatric Hospital Ouagadougou Burkina Faso Gynaeco-Obstetric Department of Bogodogo Teaching Hospital Ouagadougou Burkina Faso Radiology Department of Yalgado Ouedraogo Teaching Hospital Ouagadougou Burkina Faso Radiology Department of Charles de Gaulle Teaching Paediatric Hospital Ouagadougou Burkina Faso

Objective: To determine the diagnostic contribution of breast microbiopsy percutaneously under ultrasound guidance. Methodology: Retrospective descriptive study conducted from January 2014 to October 2017. The included patients had an ultrasound-guided breast microbiopsy after a mammographic and ultrasound scan. The variables collected were gender, age, nodule size, ACR classification and anatomopathologic diagnosis. Results: 347 nodules were explored in 313 patients. There were 300 women (95.85%) and 13 men (4.15%), a gender ratio of 23.07. The average age was 44.64 ± 14.18 years. The average size of the nodules was 30.33 ± 19.58 mm. There were 53.89% ACR4 grade nodules, 48% ACR5 nodules and 32.28% ACR3 nodules. 86.49% of ACR3 nodules were benign and 97.92% of ACR5 nodules were actually malignant. Malignant tumors accounted for 50.29% of the nodules and were dominated by invasive breast carcinomas in 98.26%. The average age of patients with malignant tumors was 49.15 ± 11.55 years. 16% of patients with malignancy were aged under 40 years old. Conclusion: The diagnostic yield was satisfactory and there was a good correlation between the rate of malignant and benign lesions and the positive predictive values of malignancy in the literature.

关键词： Breast microbiopsy Ultrasound Guidance Mammary Nodule Breast Cancer

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