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A review of microbial laccase production and activity toward different biotechnological applications

Systems Microbiology and Biomanufacturing 2023年第4期3卷 533-551页

作者： Monalisa Mahuri Manish Paul Hrudayanath Thatoi Department of Biotechnology Maharaja Sriram Chandra Bhanjadeo UniversitySriram Chandra ViharTakatpurBaripadaOdisha 757003India

laccases are versatile enzymes that belong to the multi-copper oxidase *** enzyme has several biotechnological applications because of its ablilty to oxidize a wide range of phenolic and non-phenolic ***,their large-scale applicability in bioremediation and water treatment is hindered by high salt content and extreme pH values of the polluted media which also affects the stability,recovery and recycling of *** from some bacteria,laccase is abundantly present in several lignin-degrading white-rot fungi ***,Deuteromycetes,and ***,lac-case has been employed in the development of biosensors as a medical diagnostic tool,biofuel cells,and in bioremediation purpose to remove herbicides,pesticides,and some toxic chemicals from the ***,most of the enzymes including laccase are normally unstable and susceptible to lose their activity over *** might be avoided by maintaining the activity and lengthening the enzyme's lifespan through the use of appropriate immobilization *** potential of laccase immobilized biocathodes for dye decolorization in microbial fuel cells has recently been *** laccase nanoparticles have potential uses as biocatalyst in the bioremediation of *** addition,advanced research considering microbial laccase has been conducted for its heterologous expression along with in silico protein engineering to attain maximum enzyme activity which can be potentially applied in different biotechnological *** related to laccase also implied that this enzyme can be used as suitable catalyst for the production of promising anti-cancer drugs and even as a significant ingredient in cosmetics.

关键词： microbial laccase laccase activity Membrane immobilization Heterologous expression In silico protein engineering Bioremediation

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