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Metastasis to the thyroid gland from primary breast cancer presenting as diffuse goiter:A case report and review of literature

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World Journal of Clinical Cases 2022年第3期10卷 1106-1115页

作者： Wen Wen Heng Jiang Hsin-Yu Wen Yu-Lan Peng Department of Ultrasound West China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina College of Medicine University of Nebraska Medical CenterOmahaNE 68133United States Department of Pathology West China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina

BACKGROUND Metastasis to the thyroid gland(TM)from primary breast cancer is uncommon and usually presents as thyroid nodules;however,diffuse goiter without thyroid nodules is the first sign of TM in rare *** metastases(SMs)to the lymph nodes in breast cancer,defined as discontiguous higher-level metastases in the absence of lower levels of contiguous metastases,have been reported in the contralateral cervical area of the primary tumor site in rare *** SUMMARY A 49-year-old previously healthy Chinese woman was diagnosed with right lateral invasive ductal carcinoma and underwent neoadjuvant chemotherapy treatment and bilateral mastectomy with axillary lymph node *** malignancy of the left breast or axillary or distant metastases were identified ***,enlarged left cervical lymph nodes were detected 36 mo after surgery,and rapidly enlarging thyroid glands without nodules were detected 42 mo after ***-needle aspiration cytology was performed on the left cervical lymph nodes and left lobe of the thyroid,which were both revealed to contain metastases from the primary breast ***,the immunostaining profiles changed in the process of *** patient was discharged with the NP(vinorelbine and cisplatin)regimen for subsequent treatment,and stable disease was determined when the curative effect was *** Diffuse goiter may be the first sign of TM,and enlarged lymph nodes in the contralateral cervical area may be SMs of primary breast cancer.

关键词： metastases to the thyroid gland Diffuse goiter Cervical lymph node recurrence Breast cancer Case report

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