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mesothelial cyst of uterine corpus misdiagnosed as leiomyoma

Chinese Medical Journal 2019年第12期132卷 1502-1503页

作者： Shi-Ping Mo Meng-Yao Wang Jin-Ke Li Department of Obstetrics and Gynecology West China Second HospitalSichuan UniversityChengduSichuan 610041China Key Laboratory of Birth Defects and Related Diseases of Women and Children Ministiy of EducationSichuan UniversityChengduSichuan 610041China

A 46-year old woman (gravida 3, para 1) presented at West China Second Hospital with complaints of a space-occupying lesion in the uterus that, 2 years before, had been diagnosed as a uterine cyst at West China Second Hospital. On that previous occasion, B-ultrasonography revealed a cystic mass with a compartmentalized structure (10.3 × 5.4 × 8.8 cm) on the left side of the pelvic cavity, and laparoscopic exploration found a cystic mass on the posterior uterine wall, which was diagnosed as "leiomyoma with cystic degeneration" based on pathology analysis of flash-frozen surgical tissues. Laparoscopic "myomectomy" was performed, and pathology analysis of paraffin-embedded tissue confirmed "leiomyoma with degeneration." Immunohistochemistry showed the lesion to be positive for caldesmon but negative for CD10. Rate of Ki67 positivity was less than 1%, indicating a benign lesion. The woman recovered well after the operation. Follow-up ultrasonography at 3 months after surgery identified a uterine cystic mass of 3.0 × 2.5 × 1.7 cm.

关键词： mesothelial cyst uterine corpus as leiomyoma

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Investigation of Open Abdomen Visceral Skin Graft Revascularization and Separation from Peritoneal Contents

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Surgical Science 2018年第1期9卷 24-43页

作者： Katharine E. Caldwell Ross M. Clark Brittany B. Coffman Jacquelyn S. Brandenburg Thomas R. Howdieshell Departments of Surgery University of New Mexico Health Sciences Center Albuquerque USA Pathology University of New Mexico Health Sciences Center Albuquerque USA

Background: Despite increasing survival following damage control laparotomy and open abdomen technique, little is known about the biology of visceral skin graft revascularization and separation from peritoneal contents. Methods: Following laparotomy for trauma, patients with visceral edema preventing fascial closure underwent Vicryl mesh closure followed by visceral split-thickness skin grafting and readmission graft excision and abdominal wall reconstruction. Utilizing laser speckle contrast imaging, immunochemical staining of histologic sections, and RT-PCR array technology, we examined the revascularization, microvascular anatomy, morphology, and change in gene expression of visceral skin grafts. Results: Ten patients ranging in age from 25 to 46 years underwent visceral grafting for cutaneous coverage of an open abdomen. Skin graft perfusion peaked at a mean of 350 PU by post-operative day 14 synchronous with closure of meshed interstices, and remained constant until excision. Time to graft excision ranged from 6 to 18 months. CD-31 immunostaining documented a significant (p = 0.04) increase in vascular surface area in excised grafts compared to control skin. Trichrome staining revealed an 8-fold increase in excised graft thickness. mesothelial cells were identified within the dermal matrix of excised grafts. RT-PCR demonstrated significant up-regulation of genes involved in matrix structure and remodeling, cytoskeleton regulation, and WNT signaling;and down-regulation of genes involved in inflammation and matrix proteolysis in excised grafts compared to control skin. Conclusion: Our data document early visceral skin graft perfusion and a plateau in revascularization. Histology reveals a robust dermal matrix populated by fibroblasts and mesothelial cells within a complex supporting vascular network. Genetic analysis of excised grafts reveals growth factor, collagen, and matrix remodeling gene expression.

关键词： Open Abdomen Visceral Skin Graft mesothelial Cells

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Unusual Location of Coelomic Cysts

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Open Journal of Respiratory Diseases 2018年第3期8卷 33-37页

作者： Smadhi Hanen Ben Jemai Emna Diouani Mohamed Fethi Abdennadhar Mahdi Attia Monia Ayadi-Kaddour Aida Megdiche Mohamed Lamine Department of Pneumology Ibn Nafis Abderrahman Mami University Hospital Ariana Tunisia Faculté de Médecine de Tunis Université Tunis El Manar Tunis Tunisia. Faculté des Sciences de Bizerte Université de Carthage Carthage Tunisia. Laboratoire d’Epidémiologie et de Microbiologie Vétérinaire Institut Pasteur de Tunis Tunis Tunisia Department of Thoracic Surgery Abderrahman Mami University Hospital Ariana Tunisia Department of Radiology Abderrahman Mami University Hospital Ariana Tunisia Department of Pathology Abderrahman Mami University Hospital Ariana Tunisia

Intrathoracic mesothelial cysts are congenital lesions due to an abnormal development of the pericardial coelom. They are generally unilocular and can develop in various sites. We describe a case of multicystic lesions in the anterior mediastinum of a 53-year-old woman discovered in a context of an encysted pleural effusion. Chest computed tomography (CT) scan revealed multiple cystic lesions in the anterior and posterior mediastinum. Surgery was carried out and histopathology and immunohistochemistry confirmed the diagnosis of multiple coelomic cysts of the mediastinum.

关键词： mesothelial Cysts Mediastinum Surgery Pathology

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