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作者： BIJAY PARIYAR 重庆医科大学

学位级别：硕士

The structure of the menisci allows the effective distribution of load across the knee *** though our first priority goes to meniscus-preserving surgery,but many tears are irreparable,and many repairs are not *** is widely accepted that partial meniscectomy leads to early onset of osteoarthritis(OA).meniscal allograft transplantation(MAT)was developed as a means of treating the symptoms of compartmental overload after meniscectomy and numerous case series have reported a significant improvement in knee function with reasonable rates of complication and survival,but randomized controlled trials have not been *** allograft transplantation has been performed for more than 30 years and numerous case series have consistently reported as protective of *** main goal of this review article is to provide an overview and current status of the role of MAT and also discussed the directions to advance the MAT in the future.

关键词： meniscal allograft transplantation meniscus replacement meniscus repair meniscectomized knee

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Macroscopic and Histological Evaluations of meniscal AIIograft transplantation Using Gamma Irradiated Meniscus： A Comparative in Vivo Animal Study

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Chinese Medical Journal 2015年第10期128卷 1370-1375页

作者： Jin Zhang Guan-Yang Song Xing-Zuo Chen Yue Li Xu Li Jun-Lin Zhou Department of Orthopaedics Beijing Chao Yang Hospital Capital Medical University Beijing 100020 China Sports Medicine Service Beijing Jishuitan Hospital Beijing 100035 China Department of Orthopaedic Trauma China-Japan Friendship Hospital Beijing 100029 China

Background：Many studies suggest that the gamma irradiation decreases allograft strength in a dose-dependent ***,no study has demonstrated that this decrease in strength translates into higher failure rate in meniscal allograft transplantation （MAT）.The aim of this study was to investigate the effects of gamma irradiation on macroscopic and histological alterations of transplanted meniscal tissue and joint cartilage after ***：Medial total meniscectomies were performed on the right knees of 60 New Zealand white *** meniscal allografts were divided into three groups （20 in each group） and then sterilized with 0 Mrad,1.5 Mrad,or 2.5 Mrad of gamma *** each group,5 menisci were randomly chosen for scanning electron microscopic （SEM） analysis and the remaining 15 were prepared for MAT ***-five right knees received MAT surgeries （0 Mrad group,1.5 Mrad group,2.5 Mrad group,15 in each group）,whereas the remaining 15 only received medial meniscectomy （Meni group）.The left knees of the Meni group were chosen as the Sham group （n =15）.All the rabbits were sacrificed at week 24 *** of the medial compartment of each group was evaluated macroscopically using the International Cartilage Repair Society （ICRS） score and then histologically using the Mankin score based on the Masson Trichrome ***：The SEM analysis confirmed that the meniscal collagen fibers would be significantly damaged as the dose of gamma irradiation *** week 24,the overall scores of macroscopic evaluations of the transplanted meniscal tissue showed no significant differences among the three groups receiving MAT surgeries,except for 2 in the 2.5 Mrad group presented partial radial tears at *** ICRS scores and the Mankin scores showed the lowest in the Sham group and the highest in the Meni group （P 〈 0.05）.For the three groups receiving MAT surgeries,the 2.5 Mrad group showed significant higher ICRS scores and Manki

关键词： Gamma Irradiation Histological Macroscopic meniscal allograft transplantation

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Discoid meniscus:Treatment considerations and updates

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World Journal of Orthopedics 2024年第6期15卷 520-528页

作者： Waleed Albishi Amjad Albaroudi Abdulrahman M Alaseem Sarah Aljasser Ibrahim Alshaygy Abdullah Addar Department of Orthopedic Surgery College of MedicineKing Saud UniversityRiyadh 11362Saudi Arabia

A discoid meniscus is a morphological abnormality wherein the meniscus loses its normal‘C’*** most patients are asymptomatic,patients might still present with symptoms such as locking,pain,swelling,or giving *** resonance imaging is usually needed for confirmation of *** on a constellation of factors,including clinical and radiological,different approaches are chosen for the management of discoid *** purpose of this review is to outline the treatment of discoid meniscus,starting from conservative approach,to the different surgical options for this *** PubMed and Google Scholar databases were used for this *** discussing the treatment of discoid meniscus from 2018 to 2023 were *** there were 369 studies retrieved,and after removal of studies using the exclusion criteria,26 studies were included in this *** such as stability,presence of tear,and morphology can help with surgical *** approaches have been used to treat discoid meniscus,where the choice is tailored for each patient ***,factors that may positively impact patient outcomes include male sex,body mass indexmeniscal allograft transplantation.

关键词： Discoid meniscus Saucerization Partial meniscectomy Meniscoplasty Meniscopexy meniscal allograft transplantation Arthroscopy Knee

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