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Malignant melanocytic Matricoma and Criteria for Malignancy

Open Journal of Pathology 2018年第3期8卷 94-100页

作者： Colton B. Nielson Vladimir Vincek Department of Dermatology University of Florida College of Medicine Gainesville USA

melanocytic matricoma is a very rare adnexal tumor that recapitulates the anagen hair follicle bulb. Few cases of malignant melanocytic matricoma have been reported, thus criteria for malignant potential have not been previously reviewed. We report a case of an 81 year old male that was originally diagnosed as atypical melanocytic matricoma. The site was re-excised with a small focus of residual tumor, but all margins were negative. The re-excision site healed without complication. However, two years after the original biopsy, a new 8 mm firm nodule appeared at the re-excision site, which was subsequently diagnosed as malignant melanocytic matricoma (MMM). In the following paper we will report a new case of MMM and review potential criteria that could be used in the future to establish malignant potential.

关键词： Pigmented Malignant Pilomatricoma Malignant melanocytic Matricoma melanocytic Matrical Carcinoma Matricoma

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Intracranial Intermediate-Grade melanocytic Neoplasm: Case Report Associated with Nevus of Ota

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Open Journal of Modern Neurosurgery 2017年第3期7卷 65-74页

作者： Dorothy Sze Wing Hung Calvin Hoi Kwan Mak Fung Ching Cheung Department of Neurosurgery Queen Elizabeth Hospital Hong Kong China

melanocytic lesions of the CNS are rare tumours originating from melanocytes that are present in the leptomeninges. They consist of a spectrum of pigmented tumours ranging from melanocytoma to melanoma. A small group of these tumours have histopathological features between those of a benign melanocytoma and a malignant melanoma;these present as intermediate grade melanocytic neoplasms. Naevus of Ota is a blue hyperpigmented dermal lesion characterized by increased number of melanocytes in the distribution of ophthalmic and maxillary divisions of the trigeminal nerve. The association of an intracranial intermediate-grade melanocytic neoplasm with a nevus of Ota is extremely rare, with only 2 cases reported in the literature to date. As a result, their behavior and progression are still poorly understood. We present the first case of a familial naevus of Ota associated with intermediate-grade melanocytic neoplasm.

关键词： melanocytic Neoplasm Leptomeninges Nevus of Ota

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