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Quantitative Assessment of Chronic Skin Reactions Including Erythema and Pigmentation after Breast Conserving Therapy

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Advances in Breast Cancer Research 2016年第3期5卷 121-128页

作者： Miho Kawashima Miwako Nozaki Kazuhiro Komazaki Ryuko Yamamuro Kazuo Ishizuna Makoto Kojima Department of Radiology Dokkyo Medical University Koshigaya Hospital Saitama Japan Breast Center Dokkyo Medical University Koshigaya Hospital Saitama Japan

Purpose: To evaluate long-term skin reactions following breast-conserving therapy by using the melanin-erythema index meter. Patients and Methods: 164 patients were followed for at least three years after breast-conserving therapy. For both the erythema and the melanin indices, the ratio of the irradiated-side index to the non-irradiated-side index was calculated. The time course of index ratios alternation was examined. Influences from additional therapies and patients’ age were also evaluated. Result: Both erythema and melanin index ratios of the breast skin were recovered to pre-radiation level three years after radiotherapy. However, both index ratios of the area administrated with 10-Gy boost irradiation were still high even after five years after radiotherapy. Endocrine therapy, chemotherapy and age had no significant influence on skin color reactions three years after radiotherapy. Conclusion: Quantitative assessment using the melanin-erythema index meter demonstrated that chronic skin reactions following breast conserving therapy had recovered to pre-radiation level for three years after irradiation except for the 10-Gy boost irradiated area.

关键词： Breast Cancer Erythema index melanin index Breast-Conserving Therapy

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