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medication adherence and quality of life among type-2 diabetes mellitus patients in India

World Journal of Diabetes 2021年第10期12卷 1740-1749页

作者： Rakhi Mishra Suresh K Sharma Rajni Verma Priyanka Kangra Preeti Dahiya Preeti Kumari Priya Sahu Priyanka Bhakar Reena Kumawat Ravinder Kaur Ravinder Kaur Ravi Kant College of Nursing All India Institute of Medical SciencesUttarakhand 249203RishikeshIndia Department of Medicine All India Institute of Medical SciencesUttarakhand 249203RishikeshIndia

BACKGROUND Diabetes mellitus(DM)is a progressively increasing metabolic disorder and a significant public health burden that demands immediate global ***,there is a paucity of data about adherence to antidiabetic drugs among patients with type-2(T2)DM in Uttarakhand,*** research reported that more than 50%of patients do not adhere to the correct administration and appropriate medicine *** has been reported that patients with chronic diseases who adhere to treatment may experience improvement in quality of life(QoL)and vice *** To assess the adherence to antidiabetic medication and QoL among patients with *** This cross-sectional descriptive study was conducted at a tertiary care hospital in Uttarakhand,*** medication adherence Rating Scale and World Health Organization QoL-BREF scale were used to assess medication adherence and *** Two hundred seventy-seven patients suffering from T2DM participated in the *** mean age was 50.80(±10.6)years,155(56%)had a poor adherence level and 122(44%)had a good adherence level to antidiabetic *** adjusting for sociodemographic factors,multiple linear regression analysis found patients who were adherent to antidiabetic medications had significantly higher mean overall perception of QoL and overall perception of health,with beta scores of 0.36 and 0.34,respectively(both P=0.000)points compared with nonadherent *** There was an association between medication adherence and QoL in patients with ***,there is a need to plan awareness and counseling programs followed by regular follow-up to motivate patient adherence to recommended treatment and lifestyle regimens.

关键词： medication adherence Quality of life Diabetes mellitus Tertiary care hospital India

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medication beliefs predict medication adherence in ambulatory patients with decompensated cirrhosis

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World Journal of Gastroenterology 2017年第40期23卷 7321-7331页

作者： Kelly L Hayward Patricia C Valery Jennifer H Martin Antara Karmakar Preya J Patel Leigh U Horsfall Caroline J Tallis Katherine A Stuart Penny L Wright David D Smith Katharine M Irvine Elizabeth E Powell W Neil Cottrell Pharmacy Department Princess Al-exandra Hospital The Centre for Liver Disease Research Translational Research Institute The University of Queensland Cancer and Chronic Disease Research Group QIMR Berghofer Medical Research Institute School of Medicine and Public Health The University of Newcastle The Centre for Liver Disease Research Translational Research Institute The University of Queensland Department of Gastroenterology and Hepatology Princess Alexandra Hospital The Centre for Liver Disease Research Translational Research Institute The University of Queensland Department of Gastroenterology and Hepatology Princess Alexandra Hospital Statistics Unit QIMR Berghofer Medical Research Institute School of Pharmacy The University of Queensland

AIM To investigate the impact of medication beliefs, illness perceptions and quality of life on medication adherence in people with decompensated *** One hundred adults with decompensated cirrhosis completed a structured questionnaire when they attended for routine outpatient hepatology review. Measures of self-reported medication adherence(Morisky medication adherence Scale), beliefs surrounding medications(Beliefs about Medicines Questionnaire), perceptions of illness and medicines(Brief Illness Perception Questionnaire), and quality of life(Chronic Liver Disease Questionnaire) were examined. Clinical data were obtained via patient history and review of medical records. Least absolute shrinkage and selection operator and stepwise backwards regression techniques were used to construct the multivariable logistic regression model. Statistical significance was set at alpha = *** medication adherence was " High " in 42 % o f participants, "Medium" in 37%, and "Low" in 21%. Compared to patients with "High" adherence, those with "Medium" or "Low" adherence were more likely to report difficulty affording their medications(P medication concerns relative to medication necessity beliefs(P = 0.003). People with "Low" adherence also experienced greater symptom burden and poorer quality of life, including more frequent abdominal pain(P = 0.023), shortness of breath(P = 0.030), and emotional disturbances(P = 0.050). Multivariable analysis identified having stronger medication concerns relative to necessity beliefs(Necessity-Concerns Differential ≤ 5, OR = 3.66, 95%CI: 1.18-11.40) and more frequent shortness of breath(shortness of breath score ≤ 3, OR = 3.87,95%CI: 1.22-12.25) as independent predictors of "Low"*** The association between "Low" adherence and patients having strong concerns or doubting the necessity or helpfulness of their medications should be explor

关键词： medication adherence medication beliefs Illness perceptions Quality of life Liver cirrhosis

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An mHealth intervention to improve medication adherence among patients with coronary heart disease in China: Development of an intervention

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International Journal of Nursing Sciences 2018年第4期5卷 322-330页

作者： Zhao Ni Changqing Liu Bei Wu Qing Yang Christian Douglas Ryan Jeffrey Shaw School of Nursing Duke UniversityNC27705USA West China Hospital Sichuan UniversityChengduChina Rory Meyers College of Nursing New York UniversityNYUSA

Objectives:With this study,we aimed to develop a mobile technology(mHealth)intervention to improve medication adherence among patients with coronary heart disease(CHD).Methods:The study was conducted in two phases with CHD patients from a Cardiology Department of a hospital located in *** phase was independent from the *** 1 tested the integration of the two apps-"WeChat"and"BB Reminder"-as an mHealth *** participants received the same educational materials via WeChat every two *** in the experimental group received a reminder from BB Reminder for every dose of their *** duration of Phase 1 was 30 days for each *** 2 refined the intervention,in which educational materials were sent every five days rather than every two days,and medication-taking reminders were sent daily rather than every ***:In Phase 1,an mHealth intervention was developed by integrating two mobile *** Phase 2,medication adherence increased at 30-day follow-up in both groups compared to *** the 30-day follow-up,the mean of the decrease in medication non-adherence score in the experimental group(M=1.35,SD=2.18,n=36)was more than the decrease in control group(M=0.69,SD=1.58,n=36),which means the medication adherence improved more in the experimental ***:The feasibility of using mHealth to remind CHD patients to take their medications is high.

关键词： China Coronary disease medication adherence mHealth Mobile applications

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Treatment satisfaction and medication adherence among hypertensive patients in a teaching hospital in Ekiti State, Nigeria

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Journal of Integrative Nursing 2022年第2期4卷 59-67页

作者： Oluwaseyi Abiodun AKPOR Florence Olutola OLOWOLAJU Department of Nursing Science College of Medicine and Health SciencesAfe Babalola UniversityAdo-EkitiEkiti StateNigeria

Objective:This study investigates treatment satisfaction and medication adherence among hypertensive patients attending the medical outpatient clinic of a teaching hospital in Ekiti State,*** and Methods:The study design was descriptive and cross-sectional using quantitative research strategy.A systematic sampling technique was used in selecting 270 participants;a structured questionnaire was used for data *** adherence was assessed using the 8-item Morisky medication adherence Scale,and treatment satisfaction was assessed using the 14-item Treatment Satisfaction Questionnaire for ***:The study findings revealed that majority(73.7%)of the study participants had good knowledge of hypertension,while 44.4%had a good level of treatment *** of association of participants’sociodemographic characteristics revealed age(χ^(2)=23.773,P=0.003)and occupation(χ^(2)=21.251,P=0.019)to be significantly associated with treatment *** level of medication adherence by the participants was observed to be relatively poor(50.4%).The educational status(χ^(2)=23.914,P=0.001)and monthly income(χ^(2)=10.406,P=0.034)of the participants showed significant association with medication ***:The study recommends that improving patients’understanding of their disease and treatment with subsidizing hypertensive medications by the government will enhance medication adherence.

关键词： Hypertension medication adherence morbidity mortality outpatient clinic treatment satisfaction

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Association between availability of glucose-lowering drugs in primary health institutions and diabetes patients’medication adherence:a cross-sectional study in Shandong Province,China

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Global Health Journal 2021年第2期5卷 83-89页

作者： Jiansen Yao Haipeng Wang Di Shao Jia Yin Xiaolei Guo Xiao Yin Qiang Sun Center for Health Management and Policy Research School of Public HealthCheeloo College of MedicineShandong UniversityNo.44Wenhua West RoadLixia DistrictJinan 250012China Institute for Hospital Management Tsinghua UniversityUniversity Town of ShenzhenNanshan DistrictShenzhen 518055China Key Laboratory of Health Economics and Policy Research National Health Committee of the People’s Republic of ChinaNo.44Wenhua West RoadLixia DistrictJinan 250012China Shandong Center for Disease Control and Prevention No.16992Jingshi RoadLixia DistrictJinan 250014China Shandong University Affiliated Jinan Central Hospital No.105Jiefang RoadLixia DistrictJinan 250013China

Background:Primary health care system is a critical component of diabetes care and *** article aimed to analyze the availability of glucose-lowering drugs in primary health institutions(PHIs)in China,and to explore the relationship between availability of glucose-lowering drugs and medication adherence among type 2 diabetes mellitus(T2DM)***:This cross-sectional study conducted in Shandong Province,eastern China(hereafter referred to as Shandong),between August and December *** total,2520 community-managed T2DM patients were selected from 68 PHIs in Shandong,including 62 village-level and 6 township-level *** self-developed questionnaire was used to survey the availability of glucose-lowering drugs in ***’medication adherence was assessed by four self-reported questions,and was classified as either adherent or *** statistics was used to analyze the availability of glucose-lowering drugs in PHIs and the medication adherence among the T2DM *** logistic regression models were used to explore the relationship between the availability of glucose-lowering drugs in PHIs and patients’medication ***:A total of 1866 T2DM patients prescribed with at least one glucose-lowering drug were included in *** them,58.5%patients followed their antidiabetic treatment *** village-level PHIs,the patient’s adherence rate was lower than in township-level PHIs(55.9%vs.61.1%,Padherence of T2DM ***:Poor availability of glucose-lowering products was found in PHIs in *** availability of glucose-lowering products in PHIs was positively associated with patients’medication adherence,and could be enha

关键词： Diabetes mellitus Primary health institutions medication adherence Shandong China

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Mediating role of inner strength in the relationship between medication literacy and medication adherence among kidney transplant patients

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中南大学学报（医学版） 2024年第6期49卷 961-971页

作者： WANG Liping FANG Chunhua NIE Manhua ZHU Li LIU Sai LI Haiyang Clinical Nursing Teaching and Research Section Second Xiangya HospitalCentral South UniversityChangsha 410011 Department of Kidney Transplantation Second Xiangya HospitalCentral South UniversityChangsha 410011China

Objective:Compared with long-term renal replacement therapy,kidney transplantation is the ideal treatment for end-stage renal disease(ESRD),significantly extending patient life and improving quality of *** transplant patients need to adhere to lifelong immunosuppressive medication regimens,but their medication adherence is generally poor compared with other organ transplant *** adherence is closely related to medication literacy and psychological status,yet related studies are *** study aims to investigate the current status of medication adherence,inner strength,and medication literacy in kidney transplant patients,analyze the relationships among these 3 factors,and explore the mediating role of inner strength in the relationship between medication literacy and medication ***:A cross-sectional survey was conducted from March to October 2023 involving 421 patients aged≥18 years who visited kidney transplantation outpatient clinics at 4 tertiary hospitals in Hunan *** inner strength,medication literacy,and medication adherence of kidney transplant patients were investigated using the Inner Strength Scale(ISS),the Chinese version of the medication Literacy Assessment in Spanish and English(MedLitRxSE),and the Chinese version of the Morisky medication adherence Scale-8(C-MMAS-8),*** analysis was performed to examine the effects of demographic and clinical data on medication *** analysis was conducted to explore the relationships among medication literacy,medication adherence,and inner *** variables from univariate and correlation analyses were further analyzed using multiple linear regression,and the mediating effect of inner strength was ***:Among the 421 questionnaires collected,408 were valid,with an effective rate of 96.91%.The scores of C-MMAS-8,MedLitRxSE,and ISS were 6.64±1.16,100.63±14.67,and 8.47±4.03,*** the 408 patients

关键词： inner strength medication literacy medication adherence kidney transplant patients

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Psychological Distress, Social Support and medication adherence in Patients with Ischemic Stroke in the Mainland of China

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Journal of Huazhong University of Science and Technology(Medical Sciences) 2015年第3期35卷 405-410页

作者：张洪钱海舟孟曙庆舒敏高永哲徐艳张胜名红梅熊荣红 Department of Neurology Zhongnan Hospital of Wuhan University Teaching and Research Section of Neuropsychiatry Zhongnan Hospital of Wuhan University Department of Internal Medicine International Hospital of Mongolian Medicine

Stroke research and rehabilitation have traditionally focused on the physical and functional impact of a stroke. Less attention has been given to the psychosocial factors associated with this chronic condition. By the few studies that have specifically focused on psychosocial factors in the context of stroke, poststroke depression is demonstrated to significantly influence stroke outcomes. Associations of stroke with psychological symptoms other than depression have rarely been evaluated. This study was aimed to investigate the changes of psychological stress, social support and medication adherence in patients with ischemic stroke in the mainland of China. In this study, 90 patients with hemiplegia one year after first-ever middle cerebral artery infarction（stroke group） in the Zhongnan Hospital of Wuhan University from June 2008 to June 2011 were recruited for interview. Ninety age- and sex-matched normal volunteers（control group） were also examined at the same period. The psychological distress was assessed by the Symptom Checklist 90（SCL-90）, the social support by the Social Support Rating Scale（SSRS）, and medication adherence by Morisky＇s self-reported inventory, respectively. Group differences were analyzed using unpaired-t test and chi-squared test. The results showed that total mean scores of the SCL-90 in the stroke group were higher than those in the control group（P〈0.01）. Except two dimensions, paranoid ideation and psychoticism, mean scores of the rest dimensions（including somatization, obsession-compulsion, interpersonal sensitivity, depression, anxiety, hostility, and phobic anxiety） of SCL-90 were significantly higher in the stroke group than those in the control group（P〈0.05, or P〈0.01）. The objective support, subjective support, support availability and total social support scores in the stroke group were significantly higher than those in the control group（P〈0.05, or P〈0.01）. Those in the ＂SCL-90 total scores 〉150 group＂ were significantly higher t

关键词： stroke psychological distress social support medication adherence

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Clinical effects of detailed nursing management interventions on medication adherence and disease perception in patients with drugresistant tuberculosis

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World Journal of Clinical Cases 2024年第20期12卷 4191-4198页

作者： Yan-Li Chen Ya-Qin Xie Ming-Yue Wei Dong-Mei Xu Nursing Department The First People’s Hospital of Tianmen in Hubei ProvinceTianmen 431700Hubei ProvinceChina Infectious Disease Department The First People’s Hospital of Tianmen in Hubei ProvinceTianmen 431700Hubei ProvinceChina

BACKGROUND Tuberculosis(TB)is a chronic respiratory infectious disease that considerably jeopardizes human health,and there is no effective vaccine suitable for its prevention in the entire *** To investigate the promotion of medication adherence and disease cognition in patients with drug-resistant(DR-)TB using detailed nursing *** In total,114 patients with DR-TB who were diagnosed and treated at our hospital between January 2019 and January 2023 were included in this *** in the control group(n=57)were managed with conventional nursing care,while those in the observation group(n=57)were managed with detailed nursing *** adherence,disease awareness scores,medication safety,and nursing satisfaction were compared between the two groups after the *** The post-intervention medication compliance rate was 91.23%in the observation group and 75.44%in the control group,with the former being 15.79%higher than the latter(Pmedication adherence,enhance awareness of the disease,ensure safety of medication,and improve satisfaction with nursing care.

关键词： medication adherence Detailed nursing management Drug-resistant tuberculosis Disease perception Tuberculosis

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Discrepancies between self-reported Checkf update medication in adherence and indirect measurement adherence among patients undergoing antiretroviral therapy:a systematic review

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Infectious Diseases of Poverty 2024年第4期13卷 1-13页

作者： Rujun Liao Zihuan Tang Na Zhang Lin Hu Zongqi Chang Jiayi Ren Xuefei Bai inhong Shi Sisi Fan Rong Pei Liang Du Tao Zhang Center of Infectious Diseases Research Center of Clinical Epidemiology and Evidence-Based MedicineInnovation Insititute for Integration of Medicine and EngineeringWest China HospitalSichuan UniversityChengdu 610041SichuanPeople's Republic of China Department of Epidemiology and Health Statistics West China School of Public Health and West China Fourth HospitalSichuan UniversityChengdu 610041SichuanPeople's Republic of China Sichuan Center for Disease Control and Prevention Chengdu 610041SichuanPeople's Republic of China School of Public Health Chengdu University of Traditional Chinese MedicineChengdu 611130SichuanPeople's Republic of China

Background Given the critical importance of medication adherence in HIV/AIDS treatment,this study aims to com-pare medication adherence measured by self-report(SR)and indirect measurement among antiretroviral therapy(ART)patients,exploring the differences of adherence results measured by different *** We systematically searched PubMed,Embase,and the Cochrane Library to identify all relevant literature published up to November 22,2023,without language restrictions,reporting adherence to ART measured by both SR and indirect measurement methods,while also analyzing individual and group adherence *** between SR and indirect measurement results were assessed using the Mann-Whitney U test or Wilcoxon signed-rank test,with correlations evaluated using the Pearson correlation *** one-to-one comparisons,meta-epidemiological one-step analysis was conducted,and network meta-analysis techniques were applied to compare results obtained through specific adherence assessment tools reported in the identified *** The analysis encompassed 65 original studies involving 13,667 HIV/AIDS patients,leading to 112 one-to-one comparisons between SR and indirect measurement *** significant differences were observed between SR and indirect measurement tools regarding both individual and group adherence(Padherence and 0.684 for group *** meta-epide-miological one-step analysis,SR-measured adherence was determined to be 3.94%(95%Cl:-4.48-13.44%)higher for individual adherence and 16.14%(95%Cl:0.81-18.84%)higher for group adherence compared to indirectly measured *** analysis indicated that factors such as the year of reporting and geographic region appeared to influence the discrepancies between SR and indirect ***,network meta-analysis revealed that for both individual and group adherence,the results obt

关键词： HIV AIDS Antiretroviral therapy medication adherence Self-report Meta-epidemiological one-step analysis Networkmeta-analysis

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A Comparison of Quality of Life, medication Side-Effect and adherence among Schizophrenia Patients on Conventional versus Atypical Antipsychotics

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Open Journal of Psychiatry 2023年第2期13卷 94-105页

作者： Fawaz Babandi Umar Musa Usman Zahraddeen Garba Habib Desola Shakirat Owolabi Mustapha Ibrahim Gudaji Aminu Abdullahi Taura Chikaodiri Nkeweurem Aghukwa Abubakar Sulaiman Baguda Auwalu Sani Salihu Aminu Kano Teaching Hospital Kano Nigeria Department of Psychiatry Bayero University Kano Nigeria

Quality of life (QoL) is becoming a widely accepted schizophrenia management outcome. But it is still not very clear if there are any significant differences between the conventional and atypical antipsychotics in terms of QoL improvement among people with schizophrenia (PWS). It is also imperative that antipsychotic drug-related factors, such as medication adherence and side-effect, which could directly or indirectly affect the QoL of PWS, are determined and compared among PWS on different classes of the drugs. Data were collected on Socio-demographic Characteristics, Quality of Life and medication adherence using Socio-demographic and Schizophrenia Clinical Characteristics questionnaire, World Health Organization Quality of Life (WHOQoL)-Brief, and Morisky medication adherence Scale (MMAS) respectively from 250 respondents attending a tertiary health center’s Psychiatric clinic in Kano, Nigeria. Although PWS on the two classes of antipsychotic drugs showed inequalities in different aspects and domains of QoL, as well as in the levels of adherence and side-effects, the differences were all insignificant. However, presence of drug side effects was significantly associated with lower health-related QoL in the conventional antipsychotics group (p = 0.001), and lower score in the physical domain of QoL in the atypical antipsychotics group (p = 0.044). medication adherence was found to be associated with better scores in different domains of QoL in both groups of PWS. There are no significant differences in terms of QoL, medication side-effect and adherence among PWS on the two classes of antipsychotics. However, drug side-effects and adherence were significantly and respectively associated with lower and higher scores in different domains of QoL in both groups.

关键词： Schizophrenia Antipsychotics Quality of Life medication adherence

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