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Pregnancy and Metabolic-associated Fatty Liver Disease:A Clinical Update

Journal of Clinical and Translational Hepatology 2022年第5期10卷 947-954页

作者： Sherouk Fouda Madhu Mathew Vennikandam Joseph M.Pappachan Cornelius J.Fernandez School of Health and Biomedical Sciences RMIT UniversityMelbourneVICAustralia Department of Gastroenterology and Hepatology Sparrow HospitalMichigan State University College of Human MedicineLansingMIUSA Department of Endocrinology and Metabolism Lancashire Teaching Hospitals NHS TrustPrestonUK Faculty of Science Manchester Metropolitan UniversityManchesterUK Faculty of Biology Medicine and HealthThe University of ManchesterManchesterUK Department of Endocrinology&Metabolism Pilgrim HospitalBostonUK

The intricate relationship between metabolic-associated fatty liver disease(MAFLD)and maternal complications has rapidly become a significant health threat in pregnant *** presence of MAFLD in pregnancy increases the maternal risk of metabolic complications and comorbidities for both mother and *** preexistence or development of MAFLD in pregnancy is a complex multifactorial disorder that can lead to further complications for mother and ***,as pregnant women are severely underrepresented in clinical research,there is a great need for a fair inclusion of this group in clinical *** review aims to explore the effects of MAFLD during pregnancy in the context of maternal complications and outcomes and explore the effects of pregnancy on the development and progression of MAFLD within the context of maternal obesity,altered metabolic profiles,gestational diabetes and altered hormonal *** also addressed potential implications for the presence of MAFLD during pregnancy and its management in the clinical setting.

关键词： Metabolic-associated fatty liver disease Pregnancy maternal complications Fatty liver

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Late Intrauterine Foetal Death in a Tertiary Centre of Bangladesh

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Open Journal of Obstetrics and Gynecology 2021年第9期11卷 1093-1103页

作者： Most. Sabina Yeasmin M. Jalal Uddin Rajat Sanker Roy Biswas Farah Naz Mabud Nishat Anjum Nourin Department of Obstetrics and Gynaecology Chattogram Maa-O-Shishu Hospital Medical College Chattogram Bangladesh Chattogram Maa-O-Shishu Hospital Medical College Chattogram Bangladesh Chittagong Medical College Hospital Chattogram Bangladesh

Background: Late intrauterine foetal death (IUFD > 28 weeks) is a tragedy to mothers and family members. The first step to reduce IUFD is to obtain an accurate and detailed data for IUFD. The present study was done to identify the probable causes of foetal death and determine the risk of recurrence, prevention or corrective action. Methods: This prospective observational study was conducted in a tertiary hospital during a period of one year in Chattogram Maa-O-Shishu Hospital Medical college, from January to December 2018, on all admitted pregnant women with intrauterine foetal death (>28 weeks). Detailed history, clinical examination, associated conditions, mode of delivery, foetal conditions, placenta, condition of cord and investigation reports were analyzed. Results: A total of 188 IUFD were reported amongst 8013 deliveries with its incidence 23.46/1000 live birth and recurrence rate 8.5%. Maximum (89.89%) occurred in

关键词： Intrauterine Foetal Death Antenatal Care Risk Factors Prevention maternal complications

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