检索结果-南通市图书馆

In vitro evaluation of 3D printed polycaprolactone scaffolds with angle-ply architecture for annulus fibrosus tissue engineering

引用

Regenerative Biomaterials 2019年第3期6卷 175-184页

作者： T.R.Christiani E.Baroncini J.Stanzione A.J.Vernengo Department of Biomedical Engineering Department of Chemical Engineering Rowan University201 Mullica Hill RoadGlassboroNJ 08028USA

Tissue engineering of the annulus fibrosus(AF)is currently being investigated as a treatment for intervertebral disc degeneration,a condition frequently associated with low back *** objective of this work was to use 3D printing to generate a novel scaffold for AF repair that mimics the structural and biomechanical properties of the native ***-layer scaffolds were fabricated by depositing polycaprolactone struts in opposing angular orientations,replicating the angle-ply arrangement of the native AF *** were printed with varied strut diameter and *** constructs were characterized morphologically and by static and dynamic mechanical *** surfaces were etched with unidirectional grooves and the influence on bovine AF cell metabolic activity,alignment,morphology and protein expression was studied in ***,the axial compressive and circumferential tensile properties of the scaffolds were found to be in a similar range to the native AF *** microscopy images indicated that cells were able to attach and spread on the smooth polycaprolactone scaffolds,but the surface texture induced cellular alignment and ***,immunofluorescence analysis demonstrated the aligned deposition of collagen type I,aggrecan and the AF-specific protein marker tenomodulin on the etched ***,results demonstrated the potential for using the scaffolds as a template for AF regeneration.

关键词： surface modification scaffolds materials structure 3D printing

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The challenge to improve the response of biomaterials to the physiological environment

引用

Regenerative Biomaterials 2016年第2期3卷 67-71页

作者： Nicholas A.Peppas John R.Clegg McKetta Department of Chemical Engineering College of PharmacyUniversity of Texas at Austin Department of Biomedical Engineering College of PharmacyUniversity of Texas at Austin Institute for Biomaterials Drug Delivery and Regenerative MedicineCollege of PharmacyUniversity of Texas at Austin Department of Surgery and Perioperative Care Dell Medical SchoolCollege of PharmacyUniversity of Texas at Austin Division of Pharmaceutics College of PharmacyUniversity of Texas at Austin.

New applications of biomaterials often require advanced structures containing synthetic and natural components that are tuned to provide properties unique to a specific *** discuss how structural characteristics of biomaterials,especially hydrophilic ones,can be used in conjunction with non-ideal thermodynamics to develop advanced medical *** show a number of examples of biocompatible,intelligent biomaterials that can be used for organ replacement,biosensors,precise drug delivery over days or weeks,and regenerative medicine.

关键词： drug delivery nanobiomaterials regenerative mechanism materials structure

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Taking FAIR on the ChIN:The Chemistry Implementation Network

引用

Data Intelligence 2020年第1期2卷 131-138,310页

作者： Simon J.Coles Jeremy G.Frey Egon L.Willighagen Stuart J.Chalk School of Chemistry Faculty of Engineering and Physical SciencesUniversity of SouthamptonSouthampton SO171BJUK Department of Bioinformatics Maastricht UniversityMaastrichtLimburg 6200 MDThe Netherlands Department of Chemistry University of North FloridaJacksonvilleFL 32224-7699USA

The Chemistry Implementation Network(ChIN)is focused on supporting the FAIR Data needs of the research community regarding chemical related *** Implementation Network is a consortium drawn from a community,in this case the chemistry discipline,committed to defining and constructing standards,materials and software in the spirit of the FAIR data principles and under the structure of the GO FAIR ***,as a core science the ChIN has to reach beyond the chemistry community and support the use of chemical information in other *** will be facilitated through connections in the GO FAIR ecosystem of Implementation *** of the FAIR chemical concepts that need to be supported include molecular and materials structures,chemical reactions,nomenclature and other chemical terminology and *** ChIN aims to drive forward the application of the FAIR Data Principles relating to the full range of chemistry concepts that are key to the transparent and efficient communication of chemical *** the goal of FAIR chemistry data will require a culture change across the *** this is best addressed once a critical mass of tools and approaches has been developed.

关键词： Chemistry Chemical information Chemistry data Chemical data standards Infrastructure Nomenclature Molecular structure materials structure Chemical reactions Education Community engagement Endorsement and governance

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：