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Hyperinsulinemia,cancer and maqui berry:The promise of nutritional supplementation

Food Science and Human Wellness 2019年第3期8卷 264-267页

作者： Brett Deters Mir Saleem Halmos College of Natural Sciences and Oceanography NOVA Southeastern UniversityFort LauderdaleFL 33314USA

Nutritional supplementation has long been studied as a possible treatment alternative or as an adjunct to the standard treatments for common ailments and *** to the latest research,the Chilean maqui berry,Aristotelia chilensis,has been shown to reduce postprandial insulin levels by as much as fifty *** berry,which has been shown to be as effective as metformin at increasing insulin sensitivity and controlling blood glucose levels,follows a simple mechanism of action that involves the inhibition of sodium dependent glucose transporters in the small intestine,slowing the rate at which sugars enter the bloodstream and thereby decreasing blood sugar spikes and the corresponding increase in insulin *** high blood glucose levels have been proven to play a significant role in the development of cancers,as diabetics and prediabetics have been proven to have elevated risk of developing cancerous *** dietary supplementation with maqui berry may therefore indirectly reduce the risk of cancer,as well as other diseases which respond negatively to hyperglycemia and hyperinsulinemia.

关键词： Hyperinsulinemia Cardiovascular disease Diabetes Insulin maqui berry Cancer

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Ameliorating Effects of Delphinol®, Anthocyanin Standardized maqui berry Extract, on Skin Brightness and Redness in Japanese Females: A Randomized Double-Blind Placebo-Controlled Pilot Study

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Journal of Cosmetics, Dermatological Sciences and Applications 2020年第4期10卷 149-162页

作者： Norihito Shimizu Wakana Yamada Kenchi Miyasaka Hiroshi Shimoda Research & Development Division Oryza Oil & Fat Chemical Co. Ltd. Ichinomiya Japan

maqui berries are wildly grown or cultivated in the Patagonian region in Chile. The berries contain large amounts of anthocyanins, especially delphinidin glycosides, which are strong anti-oxidants. We previously reported that standardized maqui berry extract, which contained lots of anthocyanins, has ameliorative effects against dry eyes and visible light-induced photoreceptor cell damage. However, the influence of maqui berry extract on the human skin has not been evaluated even though many skin troubles are related to active oxygen species. Therefore, we conducted a randomized double-blind placebo-controlled pilot study with Delphinol®, a maqui berry extract standardized for anthocyanins, especially delphinidins and cyanidins, in healthy Japanese female subjects. Capsules containing Delphinol® (60 mg) or placebo were orally administered to subjects aged 27 to 57 years old for eight weeks. Skin conditions [pigmentation, redness, skin tone, wrinkles, texture, oil content, water content, trans epidermal water loss (TEWL), collagen score, dermal thickness, and elasticity] were measured before and after intervention. In the Delphinol® gro

关键词： maqui berry Delphinidin Glucoside Anthocyanins Skin Brightness Saturation Redness Collagen Score

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