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Generation and manipulation of chiral terahertz waves in the three-dimensional topological insulator Bi2Te3

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Advanced Photonics 2020年第6期2卷 14-22页

作者： Haihui Zhao Xinhou Chen Chen Ouyang Hangtian Wang Deyin Kong Peidi Yang Baolong Zhang Chun Wang Gaoshuai Wei Tianxiao Nie Weisheng Zhao Jungang Miao Yutong Li Li Wang Xiaojun Wu Beihang University Fert Beijing InstituteAdvanced Innovation Center for Big Data and Brain ComputingSchool of MicroelectronicsBeijingChina Beihang University School of Electronic and Information EngineeringBeijingChina Chinese Academy of Sciences Institute of PhysicsBeijing National Laboratory for Condensed Matter PhysicsBeijingChina University of Chinese Academy of Sciences School of Physical SciencesBeijingChina Beihang University Beihang-Goertek Joint Microelectronics InstituteQingdao Research InstituteQingdaoChina Wuhan National Laboratory for Optoelectronics Huazhong University of Science and TechnologyChina

Arbitrary manipulation of broadband terahertz waves with flexible polarization shaping at the source has great potential in expanding numerous applications,such as imaging,information encryption,and all-optical coherent control of terahertz nonlinear phenomena.Topological insulators featuring unique spinmomentum-locked surface state have already exhibited very promising prospects in terahertz emission,detection,and modulation,which may lay a foundation for future on-chip topological insulator-based terahertz systems.However,polarization-shaped terahertz emitters based on topological insulators with an arbitrarily manipulated temporal evolution of the amplitude and the electric-field vector direction have not yet been explored.We systematically investigated the terahertz radiation from topological insulator Bi2Te3 nanofilms driven by femtosecond laser pulses and successfully realized the generation of efficient chiral terahertz waves with controllable chirality,ellipticity,and principal axis.The convenient engineering of the chiral terahertz waves was interpreted by a photogalvanic effect(PGE)-induced photocurrent,while the linearly polarized terahertz waves originated from linear PGE-induced shift currents.Our work not only provides further understanding of femtosecond coherent control of ultrafast spin currents but also describes an effective way to generate spin-polarized terahertz waves at the source.

关键词： spin-polarized terahertz manipulation topological insulator photogalvanic effect

HYBRID POSITION/FORCE manipulation OF MULTIFINGERED HAND

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Chinese Journal of Aeronautics 1998年第2期11卷 64-72页

作者：管贻生张启先李泽湘 Robotics Research Institute Beijing Univ. Aero. and Astronaut. Beijing 100083 China Dept. of Elec. and Electron. Eng. Hong Kong Univ. of Sci. and Technol. Hong Kong

manipulation of an object interacting with the environment is investigated. Two concepts, position manipulation and force manipulation, and their corresponding schemes are presented, respectively. Then they are combin... 详细信息

关键词： multifingered hand manipulation hybrid control kinematics

N^(6)-adenosine methylation(m^(6)A)is involved in the life and death decisions of T cells

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Cellular & Molecular Immunology 2023年第4期20卷 316-317页

作者： J.J.A.Cali J.van Loosdregt Center for Translational Immunology University Medical Center UtrechtUtrechtThe Netherlands Pediatric Immunology&Rheumatology Wilhelmina Children's HospitalUniversity Medical Center UtrechtUtrechtThe Netherlands

N6-adenosine methylation (m^(6)A) is the most abundant modification observed in mRNA transcripts. It is a dynamic modification that is performed by members of the so-called writer complex (including Wtap, Virma and Mettl3) and that can be removed by so-called eraser proteins [1]. In addition, m^(6)A is recognized by reader proteins (including Ythdf2) that can exert a response. Readers and m^(6)A can modify virtually all mRNA processes, including RNA splicing, secondary structures, nuclear export and transcript stability [1]. The functional relevance of m^(6)A-mediated regulation in specific cell types and treatment conditions remains only partly understood. In T cells, earlier studies have demonstrated a relevant role for m^(6)A in T effector (Teff), T follicular helper (TFH) and T regulatory (Treg) cells through manipulation of m^(6)A pathway genes in mice [2,3,4,5,6]. In these studies, disruption of m^(6)A resulted in dysregulation of gene expression patterns and caused colitis and systemic autoinflammatory disease. In a recent study by Ito-Kureha et al., the authors set out to further understand how m^(6)A signaling affects T-cell functions by manipulating Wtap in select T cells with a murine knockout model [7]. They found that m^(6)A signaling controls many aspects of T-cell immunobiology: activation, proliferation, life, and death.

关键词： manipulation life

Improvement of drought resistance through manipulation of the gibberellic acid pathway

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Ornamental Plant Research 2021年第1期1卷 91-97页

作者： Yaping Zhang Ayla Norris Michael S.Reid Cai-Zhong Jiang Department of Plant Sciences University of California at DavisCA 95616USA Crops Pathology and Genetic Research Unit USDA-ARSDavisCA 95616USA

Improving plants'ability to survive under drought is of great importance to the horticultural industry.The plant hormone gibberellic acid(GA)mediates diverse aspects of plant growth and development.The Arabidopsis gibberellin acid insensitive mutant gai-1 displays reduced plant height,altered GA response,and enhanced drought resistance.However,over-expression of gai-1 using the constitutive 35S promoter results in dwarf plants with drought resistance.Here,we tested the hypothesis that the temporary inhibition of cell growth caused by inducible expression of the gai-1 gene would lead to better drought resistance and improve crop productivity without an undesirable dwarf phenotype.We generated transgenic plants in which the gai-1 gene was over-expressed in petunia,under a stress-inducible RD29A promoter from Arabidopsis.When these plants were subjected to limited irrigation and drought treatments,transgenic plants showed phenotypes of darker green leaves and compact flowers compared to the wild type plants.Importantly,these transgenic plants recovered sooner than wild type and the empty vector-transformed control plants.This study provides evidence that temporary inhibition of cell growth caused by over-expression of the gai-1 mutant gene with a drought stress-inducible promoter leads to better drought resistance when the plants experience drought conditions.Citation:Zhang Y,Norris A,Reid MS,Jiang CZ.2021.Improvement of drought resistance through manipulation of the gibberellic acid pathway.

关键词： drought resistance manipulation

A Review of Ultrasonic Nano manipulation Technology

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Journal of Harbin Institute of Technology(New Series) 2016年第1期23卷 1-9页

作者： Junhui Hu State Key Lab of Mechanics and Control of Mechanical Structures Nanjing University of Aeronautics and Astronautics

Nano manipulation technology has great potential applications in the assembly,measurement and fabrication of nano materials,actuating and high-sensitivity sensing of biological samples,manufacture of nano sensors,decontamination of air and water,etc. As an actuating technology which is far from being mature,the nano manipulation still faces lots of challenges in the device principles,design,scaling up,sample safety,etc.The ultrasonic nano manipulation, in which nanoscale objects are handled and actuated by controlled ultrasound,is an emerging technology to meet some of challenges in nano manipulations. The author's research team and other groups have proposed and realized a series of nano manipulation functions such as trapping,transfer, rotation and concentration since 2012, by controlled ultrasound. Compared with other nano manipulating techniques,the ultrasonic method has the merits such as very low temperature rise at the manipulation area,little selectivity to the material properties of manipulated samples,capability of being implemented on the substrates without MENS or NEMS structure,etc. This paper reviews the progresses in principles,functions,structures and characteristics of the ultrasonic devices for nano manipulations.

关键词： nano manipulation ultrasound acoustic streaming

Cerebral functional manipulation of repetitive transcranial magnetic stimulation in cognitive impairment patients after stroke:an fMRI study

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中华物理医学与康复杂志 2022年第10期44卷 911-911页

Objective This study aims to figure out cerebral functional manipulation of rTMS in patients with PSCI through using the resting-state functional magnetic resonance imaging (rs-fMRI).Methods Thirty patients with PSCI were recruited and randomly allocated into two groups: the rTMS intervention group and control group. The rTMS intervention group was given 20 min of 5 Hz rTMS (or control) over left dorsolateral prefrontal cortex (DLPFC) besides routine cognitive intervention training for 3 consecutive weeks, five times per week, on weekdays. Cognition performance was assessed by the Minimum Mental State Examination (MMSE) and Montreal cognitive assessment (MoCA). Neural activity and functional connectivity (FC) changes were acquired by rs-fMRI with fractional amplitude of low-frequency fluctuation (fALFF) and seed-based correlation analysis.Results Cognition improvements were observed both in rTMS intervention group and control group (P<0.01), while the rTMS group got more significant improvent than control group (P<0.05). To be specified, compared with the control group, the rTMS group got higher fALFF values in these brain regions including superior temporal gyrus, inferior frontal gyrus and parahippocampal gyrus, while lower fALFF values in middle temporal gyrus, middle frontal gyrus and fusiform gyrus. In addition, the rTMS group showed increased FC between LDPFC and toprecuneus, inferior temporal gyrus, middle and inferior frontal gyrus and marginal gyrus, while decreased FC between LDPFC and middle temporal gyrus and thalamus.Conclusions The increase and decrease of neural activity and FC in cognition-related regions detected by rs-fMRI are good indicators to clarify the underlining mechanisms of rTMS on PSCI.

关键词： manipulation patients stimulation

Treatment of tiny intracranial aneurysms with guidewire manipulation

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Chinese Neurosurgical Journal 2018年第1期4卷 16-21页

作者： Yuhua Jiang Youxiang Li Department of interventional neuroradiology Beijing Neurosurgical Institute and Beijing Tiantan HospitalCapital Medical UniversityBeijingChina Beijing Interventional Neuroradiology Engineering Technology Research Center 6Tiantan XiliChongwenBeijing 100050People's Republic of China

Background:Tiny false intracranial rupture aneurysms are particularly rare. It is challenged both to neurosurgery and endovascular treatment.Methods:We present here five rare cases of perforator tiny aneurysms that were diagnosed based on DSA. These patients were found due to SAH, and they decided to treat these aneurysms with endovascular therapy. After numerous attempts, the coiling microcatheter failed to access the aneurysms. As a result, the aneurysms finally were treated with guidewire manipulation.Results:Mean follow-up time was about 10.4 months. The outcomes of the 5 cases were all surprisingly excel ent. The patients were followed up with angiography and telephone till now. No revascularization of aneurysm was found.Conclusions:This paper demonstrated for the first time to our knowledge that tiny false intracranial aneurysm may be treated with guidewire manipulation. While larger studies with long-term follow-up are required to validate these promising results, guidewire manipulation is a new approach worth considering when microcatheter cannot enter aneurysm.

关键词： Intracranial aneurysm Rupture Guidewire manipulation Endovascular intervention Tiny aneurysm

STUDIES ON REDUCING AND REINFORCING manipulation OF ACUPUNCTURE DURING THE PAST 4 YEARS

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Journal of Traditional Chinese Medicine 1994年第4期14卷 226-232页

作者：麻颖刘炜宏 Institute of Acupuncture and Moxibustion China Acedemy of Traditional Chinese MedicineBeijing 100700

Acupuncture manipulation, the pro-cesses from insertion to withdrawal of theneedle, is an important factor in upgradingtherapeutic effect, especially the manipula-tion of reducing and reinforcing when theneedling sens... 详细信息

关键词： acupuncture manipulation sensation Acupuncture reinforcing withdrawal stimulation needle acupoint lifting

Discussion　on　Reinforcing　and　Reducing　manipulation　of　Yin　and　Yang　in　Acupuncture

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中国针灸 1995年第S2期15卷 351-352页

作者： Zhang Changzhi(Cerebral Institute,52935 Unit of the PLA)Zhao Xhuancha Wang Junhong,(Outpatient Department,52935 Unit of the PLA)

ＤｉｓｃｕｓｓｉｏｎｏｎＲｅｉｎｆｏｒｃｉｎｇａｎｄＲｅｄｕｃｉｎｇＭａｎｉｐｕｌａｔｉｏｎｏｆＹｉｎａｎｄＹａｎｇｉｎＡｃｕｐｕｎｃｔｕｒｅ￥ＺｈａｎｇＣｈａｎｇｚｈｉ（ＣｅｒｅｂｒａｌＩｎｓｔｉｔｕｔｅ，５２９３... 详细信息

ＤｉｓｃｕｓｓｉｏｎｏｎＲｅｉｎｆｏｒｃｉｎｇａｎｄＲｅｄｕｃｉｎｇＭａｎｉｐｕｌａｔｉｏｎｏｆＹｉｎａｎｄＹａｎｇｉｎＡｃｕｐｕｎｃｔｕｒｅ￥ＺｈａｎｇＣｈａｎｇｚｈｉ（ＣｅｒｅｂｒａｌＩｎｓｔｉｔｕｔｅ，５２９３５ＵｎｉｔｏｆｔｈｅＰＬＡ）Ｚｈａ...

关键词： Acupuncture Discussion Yin Reducing Reinforcing Yang manipulation and of