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lymphoepithelial cyst of the pancreas: a case report

Hepatobiliary & Pancreatic Diseases International 2004年第1期3卷 155-157页

作者： Xiao-Ping Zou Yu-Mei Li Zhao-Shen Li Guo-Ming Xu Department of Internal Medicine Changhai Hospital Second Military Medical University Shanghai 200433 China. zxpfcp@***

BACKGROUND:lymphoepithelial cyst of the pancreas is a rare lesion of undetermined pathogenesis that had been documented almost exclusively in males. The literature on this entity is limited to reports of single or a small number of cases.METHODS:The case we described herein was compared with a total of 36 cases reported elsewhere.RESULTS:The 37 cases of lymphoepithelial cyst of the pancreas including our case were reviewed. lymphoepithelial cysts have uniform and distinctive clinicopathologic features. Approximately 46% of the reported cases were asymptomatic with the lesions found incidentally, and their symptoms were non-specific.CONCLUSIONS:lymphoepithelial cyst is a rare benign lesion of the pancreas. Fine-needle aspiration biopsy (FNAB) is a rapid and reliable technique that can be used as the first diagnostic step in cases of cystic lesions of the pancreas.

关键词： lymphoepithelial cyst pancreas

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lymphoepithelial cysts and cystic lymphangiomas: Underrecognized benign cystic lesions of the pancreas

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World Journal of Gastrointestinal Surgery 2014年第7期6卷 136-141页

作者： Ioannis T Konstantinidis Avinash Kambadakone Onofrio A Catalano Dushyant V Sahani Vikram Deshpe David G Forcione Jennifer A Wargo Carlos Fernandez-del Castillo Keith D Lillemoe Andrew L Warshaw Cristina R Ferrone Departments of Surgery Massachusetts General HospitalBoston MA 02114 United States Department of Surgery University of ArizonaTucson AZ 85724 United States Departments of Radiology Massachusetts General Hos-pitalBoston MA 02114 United States Department of Radiology University of Napoli80138 Napoli Italy Departments of Pathology Massachusetts General HospitalBoston MA 02114 United States Departments of Gastroenterology Massachu-setts General HospitalBoston MA 02114 United States

AIM: To identify their diagnostic and prognostic clinical characteristics in a large ***: Retrospective review of clinicopathologic and imaging characteristics of patients diagnosed with lymphoepithelial cysts and cystic lymphangiomas of the pancreas at Massachusetts General ***: Twelve patients were identified between 1/1/1997 and 8/1/2007. Their median age was 55.5 years(range 19-78 years), and 6 were females. The le-sion was incidentally discovered in half of the *** enhanced computed tomography demonstrat-ed that the cysts had thin walls, without calcifications, pancreatic duct dilation or pancreatic parenchyma inva-sion. Endoscopic ultrasound with fine needle aspiration(EUS/FNA) confirmed the diagnosis of a lymphoepithe-lial cyst in 3 patients, one of whom was spared an op-eration and continues to do well after 6 years. Eleven patients had a resection: 3 pancreaticoduodenecto-mies, 7 distal pancreatectomies, and 1 enucleation. The median size of the cysts was 3 cm(range 2-20 cm). At a median follow-up of 57 mo no recurrences or other pancreas-related conditions ***: lymphoepithelial cysts and cystic lymphangiomas of the pancreas can be diagnosed with a combination of contrast-enhanced computed tomog-raphy scans and EUS/FNA. If the lesion is asymptom-atic, an operation might be avoided.

关键词： lymphoepithelial cysts Cystic lymphangio-mas Pancreas Asymptomatic cysts Benign cystic le-sions of the pancreas

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Primary mucosa-associated lymphoid tissue lymphoma of the liver: A report of two cases and review of the literature

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World Journal of Hepatology 2017年第3期9卷 155-160页

作者： Ifeyinwa E Obiorah Lynt Johnson Metin Ozdemirli Department of Pathology Medstar Georgetown University Hospital Department of Surgery Medstar Georgetown University Hospital

Mucosa-associated lymphoid tissue(MALT) lymphoma of the liver is a very rare condition and thus the diag-nosis may be challeng-ing-. The clinical presentation is usually variable, rang-ing- from minimal clinical symptoms to severe end stag-e liver disease. In this paper, we describe the clinicopatholog-ic finding-s in two cases of primary hepatic MALT lymphoma. One case is an 80-year-old female with no underlying- chronic liver disease and the second case is a 30-year-old female with autoimmune hepatitis complicated by MALT lymphoma. In both specimens, there was diffuse infiltration of atypical B-lymphocytes that were positive for CD20 and CD79 a, but neg-ative for CD5, CD43 and CD10. There were occasional lymphoepithelial lesions involving- the hepatocytes or bile ducts. Polymerase chain reaction analysis showed monoclonal immunog-lobulin heavy chain g-ene rearrang-ement in both cases. The first case was treated with surg-ery but developed pulmonary recurrence a year after complete resection but went into remission following- treatment with rituximab. A second recurrence occurred in the rig-ht parotid g-land 7 years later, which was treated with idelalisib. The second case was effectively treated with rituximab. To our knowledg-e, the second case is the first reported case linked to autoimmune hepatitis.

关键词： Extranodal Mucosa-associated lymphoid tissue lymphoepithelial Lymphoma Polymerase chain reaction

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