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Image of tumor metastasis and inflammatory lymph node enlargement by contrast-enhanced ultrasonography

World Journal of Radiology 2011年第12期3卷 298-305页

作者： Takaya Aoki Fuminori Moriyasu Kei Yamamoto Masafumi Shimizu Masahiko Yamada Yasuharu Imai Department of Gastroenterology and Hepatology Tokyo Medical University 6-7-1NishishinjukuShinjyuku-kuTokyo 160-0023Japan

AIM:To compare the difference between tumorinduced lymph node enlargement and inflammation-induced lymph node enlargement by contrast-enhanced ultrasonography and pathological findings. METHODS:A model of tumor-induced lymph node metastasis was prepared by embedding a VX2 tumor into the hind paws of white rabbits.A model of inflammation-induced enlargement was prepared by injecting a suspension of Escherichia coli into separate hind paws of white ***,a solution of SonazoidTM(GE Healthcare,Oslo,Norway)was injected subcutaneously in the proximity of the lesion followed by contrast-enhanced ultrasonography of the enlarged popliteal lymph nodes. RESULTS:In the contrast-enhanced ultrasonography of the tumor-induced metastasis model,the sentinel lymph node was *** area of filling defect was observed in that enlarged lymph *** the histology examination,the area of filling defect corresponded to the metastatic lesion of the ***-enhanced ultrasonography of the model on inflammation-induced lymph node enlargement,and that of the acute inflam-mation model performed 3-7 d later,revealed dense staining that was comparatively *** pathological findings showed acute lymphadenitis mainly due to infiltration of inflammatory ***-enhanced ultrasonography that was performed 28 d post-infection in the acute inflammation model showed speckled ***-induced cell infiltration and fiberization,which are findings of chronic lymphadenitis, were seen in the pathological findings. CONCLUSION:Sentinel lymph node imaging was made possible by subcutaneous injection of ***-enhanced ultrasonography was suggested to be useful in differentiating tumor-induced enlargement and inflammation-induced enlargement of lymph nodes.

关键词： lymph node enlargement Sentinel lymph node Contrast-enhanced ultrasonography Subcutaneous injection Sonazoid^(TM)

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Mediastinal lymphadenopathy in COVID-19: A review of literature

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World Journal of Clinical Cases 2021年第12期9卷 2703-2710页

作者： Pahnwat Tonya Taweesedt Salim Surani Department of Medicine Corpus Christi Medical CenterCorpus ChristiTX 78404United States Department of Pulmonary Critical Care and Sleep Medicine Texas A and M Health Science CenterBryanTX 77807United States

A novel coronavirus disease 2019(COVID-19)is a progressive viral disease that affected people around the world with widespread morbidity and *** with COVID-19 infection typically had pulmonary manifestation but can also present with gastrointestinal,cardiac,or neurological system *** imaging in patients with COVID-19 commonly show bilateral lung involvement with bilateral ground-glass opacity and *** lymphadenopathy can be found due to infectious or non-infectious *** is commonly found to be associated with malignant diseases,sarcoidosis,and heart *** lymph node enlargement is not a typical computer tomography of the chest finding of patients with COVID-19 *** summarized the literature which suggested or investigated the mediastinal lymph node enlargement in patients with COVID-19 *** studies are needed to better characterize the importance of mediastinal lymphadenopathy in patients with COVID-19 infection.

关键词： Mediastinal lymphadenopathy lymph node enlargement COVID-19 Novel corona virus Long term coronavirus disease-sequala Coronavirus disease complications

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