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Effect of low versus high frequency stimulation on freezing of gait and other axial symptoms in Parkinson patients with bilateral STN DBS:a mini-review

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Translational Neurodegeneration 2017年第1期6卷 129-138页

作者： Tao Xie Mahesh Padmanaban Lisa Bloom Ellen MacCracken Breanna Bertacchi Abraham Dachman Peter Warnke Department of Neurology University of Chicago MedicineChicagoILUSA Speech and Swallowing Section Department of SurgeryUniversity of Chicago MedicineChicagoILUSA Department of Radiology University of Chicago MedicineChicagoILUSA Department of Neurosurgery University of Chicago MedicineChicagoILUSA

Some studies have shown that low frequency stimulation(LFS,most commonly 60 Hz),compared to high frequency stimulation(HFS,most commonly 130 Hz),has beneficial effects,short-term or even long-term,on improving freezing of gait(FOG)and other axial symptoms,including speech and swallowing function,in Parkinson disease(PD)patients with bilateral subthalamic nucleus deep brain stimulation(STN DBS).However,other studies failed to confirm *** seems not clear what determines the difference in response to *** in study design,such as presence or absence of FOG,exact LFS used(60 Hz versus 80 Hz),study size,open label versus randomized double blind assessment,retrospective versus prospective evaluation,medication On or Off state,total electric energy delivered maintained or not with the change in frequency,and the location of active contacts could all potentially affect the *** mini-review goes over the literature with the aforementioned factors in mind,focusing on the effect of LFS versus HFS on FOG and other axial symptoms in PD with bilateral STN DBS,in an effort to extract the essential data to guide our clinical management of axial symptoms and explore the potential underlying mechanisms as ***,LFS of 60 Hz seems to be consistently effective in patients with FOG at the usual HFS in regards to improving FOG,speech,swallowing function and other axial symptoms,though LFS could reduce tremor control in some *** LFS simply addresses the axial symptoms in the context of HFS or has other beneficial effects requires further studies,along with the mechanism.

关键词： low frequency stimulation Freezing of gait Swallowing Speech Axial symptoms DBS STN Parkinson’s disease

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Effects of low frequency external excitation on oil slug mobilization and flow in a water saturated capillary model

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Petroleum 2019年第4期5卷 375-381页

作者： Liming Dai Yihe Zhang Sino-Canada Research Center for Noise and Vibration Control at Xiamen University of Technology and the University of Regina China Industrial Systems Engineering University of ReginaReginaCanada

The present research is to experimentally study the joint effects of external pressure and vibratory excitations of low frequency on oil slug mobilization and flow in a capillary *** and after the oil slug mobilization,the flow phenomena and pressure drop variation across the model are *** distance travelled by the oil slug subjected to various external pressure and vibratory excitations are also *** experimental results obtained indicate that the external vibratory excitation acting on the model has positive effect on the flow and mobilization of the oil slug in the *** is found in the research,with the application of the excitation,the contact angle between the oil slug and tube-wall is changed;the maximum pressure required to mobilize the oil slug is reduced accordingly;and the oil slug travel distance is increased in comparing with that without external *** research contributes to the comprehension of improved liquid mobilization in porous media under the application of external *** finding of the research is significant for studying the two-phase liquid flow in porous media subjected to external excitations and provides insights for Enhanced Oil Recovery with waterflooding and vibratory stimulations.

关键词： Two-phase liquid motion Oil slug mobilization Vibratory excitation Liquid mobilization Porous media Capillary model low frequency stimulation

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