检索结果-南通市图书馆

Imaging assessment of photosensitizer emission induced by radionuclide-derived Cherenkov radiation using charge-coupled device optical imaging and long-pass filters

引用

World Journal of Radiology 2023年第11期15卷 315-323页

作者： Winn Aung Atsushi B Tsuji Kazuaki Rikiyama Fumihiko Nishikido Satoshi Obara Tatsuya Higashi Department of Molecular Imaging and Theranostics Institute for Quantum Medical ScienceNational Institutes for Quantum Science and TechnologyChiba 263-8555Japan Department of Advanced Nuclear Medicine Sciences Institute for Quantum Medical ScienceNational Institutes for Quantum Science and TechnologyChiba 263-8555Japan

BACKGROUND Radionuclides produce Cherenkov radiation(CR),which can potentially activate photosensitizers(PSs)in *** groups have studied Cherenkov energy transfer to PSs using optical imaging;however,cost-effectively identifying whether PSs are excited by radionuclide-derived CR and detecting fluorescence emission from excited PSs remain a *** laboratories face the need for expensive dedicated *** To cost-effectively confirm whether PSs are excited by radionuclide-derived CR and distinguish fluorescence emission from excited *** The absorbance and fluorescence spectra of PSs were measured using a microplate reader and fluorescence spectrometer to examine the photo-physical properties of *** mitigate the need for expensive dedicated equipment and achieve the aim of the study,we developed a method that utilizes a chargecoupled device optical imaging system and appropriate long-pass filters of different wavelengths(manual sequential application of long-pass filters of 515,580,645,700,750,and 800 nm).Tetrakis(4-carboxyphenyl)porphyrin(TCPP)was utilized as a model *** doses of copper-64(^(64)CuCl_(2))(4,2,and 1 mCi)were used as CR-producing *** and data acquisition were performed 0.5 h after sample *** image analysis was conducted by using ImageJ software(National Institutes of Health)to visually evaluate TCPP *** The maximum absorbance of TCPP was at 390-430 nm,and the emission peak was at 670 *** CR and CRinduced TCPP emissions were observed using the optical imaging system and the high-transmittance long-pass filters described *** emission spectra of TCPP with a peak in the 645-700 nm window were obtained by calculation and subtraction based on the serial signal intensity(total flux)difference between^(64)CuCl_(2)+TCPP and^(64)CuCl_(2).Moreover,the differential fluorescence images of TCPP were obtained by subtracting the^(64)CuCl_(2)image from the^

关键词： Tetrakis(4-carboxyphenyl)porphyrin Photosensitizer emission Radionuclide Cherenkov radiation Optical imaging long-pass filters

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：