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Accuracy of ultrasound to identify chronic liver disease

World Journal of Gastroenterology 2010年第28期16卷 3510-3520页

作者： Richard Allan Kerry Thoirs Maureen Phillips Division of Medical Imaging Flinders Medical CentreFlinders DriveBedford Pk5042South Australia Australia School of Health Sciences University of South AustraliaCity East CampusNorth TerraceAdelaide5000South AustraliaAustralia International Centre of Allied Health Evidence University of South AustraliaCity East CampusNorth TerraceAdelaide5000South AustraliaAustralia

AIM:To identify and assess studies reporting the diagnostic performance of ultrasound imaging for identifying chronic liver disease(CLD)in a high risk population. METHODS:A search was performed to identify studies investigating the diagnostic accuracy of ultrasound imaging for *** authors independently used the quality assessment of diagnostic accuracy studies(QUADAS)checklist to assess the methodological quality of the selected ***-observer reliability of the QUADAS tool was assessed by measuring the degree of agreement(percent agreement,κstatistic)between the reviewers for each assessment prior to a *** characteristics of each study population, sensitivity and specificity results for the index tests, and results of any testing for observer agreement were extracted from the *** Operator Characteristic plots were generated using Microsoft Excel 2003 software and used to graphically display the diagnostic performance data and to explore the relationships between the reported ultrasound techniques and study characteristics,and methodology quality. RESULTS:Twenty-one studies published between 1991 and 2009 were retained for data extraction,analysis and assessment for methodological *** of methodology quality was performed on the 21 selected studies by two independent reviewers(RA&KT) using the QUADAS assessment *** all studies the mean number of responses within the QUADAS assessment tool was 10(range 7-13)for"Yes",1(range 0-3)for"No"and 3(range 0-6)for"unclear".Interrater agreement for assessment of methodology quality was significantly greater than chance when assessing for representative spectrum,clear selection criteria, appropriate delay between reference and index tests, adequate descriptions of the index and reference tests, reference and index test blinding,and if relevant clinical information was *** studies reported moderate to high observer agreement for ultrasound ***

关键词： Chronic liver disease liver surface Systematic review Ultrasonography

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