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Prolonged Opioid-Sparing Pain Control after Hemorrhoidectomy with liposome bupivacaine: Results from a Cohort of 95 Patients

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Pain Studies and Treatment 2016年第1期4卷 5-12页

作者： Allen B. Jetmore Douglas Hagen Department of Surgery Overland Park Surgery Center Overland Park KS USA Shawnee Mission Medical Center Shawnee Mission KS USA Department of Anesthesia Anesthesia Associates of Kansas City Overland Park KS USA

The objective of this retrospective study was to examine the effects of an intraoperative injection of liposome bupivacaine on the quality and duration of postsurgical pain control, patient satisfaction, and opioid use in a cohort of patients undergoing hemorrhoidectomy in an outpatient setting. Patients underwent ambulatory hemorrhoidectomy conducted by a single surgeon. liposome bupivacaine 266 mg/20 mL was administered via infiltration at the end of surgery. After discharge, pain-related outcomes were assessed via telephone interviews. Outcomes of interest included first onset of pain after surgery, patient-reported pain intensity (0 = no pain;10 = worst pain imaginable), time to first use of orally administered opioids after surgery, number of opioid tablets consumed postsurgery, and patient’s satisfaction with postsurgical pain control. A total of 95 patients were included;the average number of hemorrhoids excised was 3.0 (median, 2.7) per patient. Mean time to first onset of pain after surgery was 36 hours;mean time to first consumption of postsurgical opioids was 38 hours. Mean pain intensity scores remained liposome bupivacaine-related adverse events were observed. A single intraoperative injection of liposome bupivacaine safely facilitated ambulatory hemorrhoidectomy, eliminated the need for intravenous opioids, minimized opioid use, and was associated with high levels of patient satisfaction.

关键词： Postoperative Pain Hemorrhoidectomy liposome bupivacaine Postoperative Analgesia

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