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China Medical Abstracts(Internal Medicine) 2014年第1期31卷 36-37页

作者：黄健 Dept Gastroenterol Affil HospAnhui Med Univ

Objective To investigate the association between MYO9B rs962917 and rs1545620 gene polymorphism and clinical pathological characteristics of patients with inflammatory bowel disease(IBD)and permeability of intestinal ... 详细信息

关键词： permeability mucosa genotype mannitol ligase matched DNA urine gender

A PRELIMINARY NOTE ON CONSTRUCTING A RICE NUCLEAR GENE LIBRARY

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Chinese Science Bulletin 1982年第3期27卷 349-350页

作者：蔡以欣谢雍汪训明贺沛富彭泽国何国顺张宝珩阎炳宗洪仁远王威 Institute of Genetics Fudan University Department of Biology Tianjin Teachers College

Using the eosmid (pHC 79) as a vector, we have constructed a nuclear gene library of the international rice IR-26 which carries several different disease resistant genes. The rice DNA was extracted and purified from the nuclei, and its molecular weight was determined to be 50-100kb. The cosmid DNA was prepared by the method of alkali denaturation. Both rice

关键词： library purified carries nuclei alkali DNA totally ligase ingle besides

CHEMICAL SYNTHESIS AND CLONING OF PRO-UROKINASE GENE

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Chinese Science Bulletin 1991年第3期36卷 264-264页

作者：邓余傅和亮薜明孙筱清闵永洁朱德煦王启松 The Institute of Genetics Fudan University Shanghai 200433 PRC Department of Biochemistry Nanjing University Nanjing 210008 PRC

Pro-urokinase is a kind of protease existing in human body. It has the character of fibrinolysis, so it has been clinically applied to the treatment of thrombolytic diseases. In order to produce a large amount of pro-urokinase by genetic engineering method and reform it with protein engineering, we have chemically synthesized the pro-urokinase gene, which

关键词： urokinase chemically clinically protease DNA ligase body intended assembling Polya

王青青教授团队发现FBXW7在抗病毒天然免疫中的调控功能

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浙江大学学报（医学版） 2017年第2期46卷 117-117页

近日，浙江大学免疫学研究所王青青教授团队在《自然一通讯》（Nature Communications）发表了研究论文“E3 ligase FBXW7 is critical for RIG-I stabilization during antlviral responses＂（https ：//www. nature, eom/articles/n... 详细信息

关键词：天然免疫抗病毒调控 ligase RNA病毒浙江大学研究论文感染过程

SPOP acts as the key regulatory hub in hypoxia induced kidney cancer

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Science Foundation in China 2015年第2期23卷 27-27页

Supported by the National Natural Science Foundation of China,the groups of *** Jiang at Beijing Institute of Genomics,CAS and *** White from the University of Chicago,reported that the E3ligase adaptor SPOP acts as the key regulatory hub in hypoxia induced tumorigenesis in kidney *** work has been published in Cancer Cell(2014,25(4):455—468).

关键词： Genomics tumorigenesis ligase Chicago cytoplasmic Carcinoma mTOR ubiquitin elucidated promoting

Understanding the modulation of c-Maf stability in multiple myeloma

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Science Foundation in China 2016年第2期24卷 28-28页

With the support of the National Natural Science Foundation of China,the research team led by *** Xinliang(毛新良)from Soochow University uncovered the molecular modulation of c-Maf stability and found a novel therapeutic strategy towards the treatment of multiple myeloma(MM).This study was recently published in Blood(Zhang et al.,2016,127:1676—1686).

关键词： myeloma Blood malignancy ubiquitin fetal ligase chromosomal elusive Figure integrin

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国外医学情报 1986年第9期 150-150页

DNA PolymeraseDNA多集酶1958年发现。此酶不合成DNA,而仅起修补作用。在一定条件下,能将4种脱氧核苷三磷酸聚合成一条DNA链。 DNA ligase DNA连接酶 1967年在五个实验室同时发现,它是细胞复制的组成部分,

关键词： DNA 脱氧核苷三磷酸 ligase 多态性能将遗传标志地中海贫血产前诊断基因表达无联系