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Study on tongue coating microbes of bitter taste,sticky and greasy taste in chronic atrophic gastritis

Journal of Traditional Chinese Medicine 2023年第1期43卷 160-167页

作者： CAO Yang GAI Xiao ZHENG Yixin Guo Benqiong NIU Jingbin QIAN Peng LING Jianghong LIU Guoping ZHENG Yu Shanghai Key Laboratory of Health Identification and Assessment School of Basic Medical SciencesShanghai University of Traditional Chinese MedicineShanghai 201203China Department of Digestive Disease Shuguang HospitalShanghai University of Traditional Chinese MedicineShanghai 200032China DepartmentⅡof Digestive Disease Longhua HospitalShanghai University of Traditional Chinese MedicineShanghai 201203China

OBJECTIVE:To objectively reveal the relationship between tongue coating microbes and bitter taste,sticky and greasy taste in chronic atrophic gastritis(CAG)***:16S rRNA high-throughput sequencing was used to detect bacterial diversity and community composition of tongue coating microbes from samples of CAG *** algorithm was used for discovering the different tongue coating microbes in CAG patients with or without bitter taste,also that in CAG patients with or without sticky and greasy ***:We respectively compared the features of tongue coating microbes in bitter taste,sticky and greasy taste of CAG *** the genus level,25 tongue coating microbes were significantly different in CAG patients with bitter taste or without bitter taste;17 tongue coating microbes were significantly different in CAG patients with sticky and greasy taste or without sticky and greasy *** and Rothia were closely related to CAG patients with bitter ***,Serratia,leptotrichia and Selenomonas were closely related to CAG patients with stick and greasy ***:Campylobacter and Rothia possibly contribute to bitter taste of CAG patients,and Enterococcus,Serratia,leptotrichia and Selenomonas contribute to stick and greasy taste of CAG patients,which is potential for the diagnosis and treatment of CAG.

关键词： gastritis,atrophic taste Campylobacter Enterococcus Serratia leptotrichia Selenomonas

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