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Effect of maternal lipid profile,C-peptide,insulin,and HBA1c levels during late pregnancy on large-for-gestational age newborns

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World Journal of Pediatrics 2014年第2期10卷 175-181页

作者： Ruo-Lin Hou Huan-Huan Zhou Xiao-Yang Chen Xiu-Min Wang Jie Shao Zheng-Yan Zhao Department of Children's Health Care Children's HospitalZhejiang University School of MedicineHangzhou 310003China Department of Endocrinology Children's HospitalZhejiang University School of MedicineHangzhou 310003China

Background:Large-for-gestational age(LGA)newborns can increase the risk of metabolic *** studies have shown that the levels of maternal blood lipids,connecting peptide(C-peptide),insulin and glycosylated hemoglobin(HbA_(1c))were significantly different between LGA and appropriate-for-gestational age(AGA)*** study aimed to determine the effect of the levels of maternal lipids,C-peptide,insulin,and HbA_(1c) during late pregnancy on LGA ***:This study comprised 2790 non-diabetic women in late *** their newborns,2236(80.1%)newborns were AGA,and 554(19.9%)newborns were *** and neonatal characteristics were obtained from questionnaires and their case *** levels of maternal fasting serum apolipoprotein A1(ApoA1),triglyceride(TG),total cholesterol(TC),high-density lipoprotein cholesterol(HDL-C),low-density lipoprotein cholesterol(LDL-C),C-peptide,insulin and blood HbA_(1c) were *** chi-square and Mann-Whitney U test were used to analyze categorical variables and continuous variables between the AGA and LGA groups,*** logistic regression analysis was made to determine the independent risk factors for LGA ***:Maternal TG,C-peptide,insulin and HbA_(1c) levels were signifi cantly higher in the LGA group than in the AGA group(Ppregnancy body mass index,education,smoking,annual household income,amniotic fluid volume,gestational hypertension,newborn gender and gestational age at blood collection,high maternal TG levels remained signifi cantly associated with LGA newborns(Plate pregnancy is signifi cantly associated with LGA newborns.

关键词： large-for-gestational-age newborns late pregnancy maternal lipid profile triglyceride

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Effect of hormonal status and metabolic changes of restricted ewes during late pregnancy on their fetal growth and development

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Science China(Life Sciences) 2007年第6期50卷 766-772页

作者： GAO Feng1, HOU XianZhi1 & LIU YingChun2 1 College of Animal Science and Animal Medicine, Inner Mongolia Agricultural University, Huhhot 010018, China 2 College of Biotechnology and Bioengineering, Inner Mongolia Agricultural University, Huhhot 010018, China College of Animal Science Animal Medicine Inner Mongolia Agricultural University Huhhot 010018 China College of Biotechnology Bioengineering Inner Mongolia Agricultural University Huhhot 010018 China

This study investigated the effects of hormonal status; metabolic changes of restricted ewes during late pregnancy on the ovine fetus growth; development. One hundred Mongolian ewes, synchronized for oestrus; mated, were divided into three groups; offered 0.175 MJME·kgw[0.75]·d[1] (Restricted Group 1, RG1), 0.33 MJME·kgw[0.75]·d[1] (Restricted Group 2, RG2); ad libitum access to feed (Control Group, CG) during their late pregnancy respectively. The results suggested that with the supply of exogenous energy decreasing during late pregnancy, maternal body weight; net body weight loss in RG2; RG1 were lower than those of CG (Ps0.01). The insulin; IGF-1 concentrations of ewes in RG2; RG1 tended to be lower than those of CG (P>0.05), but the GH concentrations in RG2; RG1 were enhanced; there was significant difference between RG1; CG on d 120 of gestation (P0.05). However, the NEFA; FAA concentrations of ewes in RG1 were reduced from d 90 to d 120 of gestation, then enhanced from d 120 to d 140 of gestation. During the late pregnancy, with the supply of nutrition decreasing, the negatively physiological; biochemical maternal reactions to restriction became worse, which significantly reduced the average lamb birth weight; daily growth rate of fetus in RG2 (P<0.05); RG1 (P<0.01).

关键词： late pregnancy restricted ewes fetus growth development

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Comparative Study on Clinical Characteristics and Outcomes of Overt Diabetes Mellitus and Gestational Diabetes Mellitus in late pregnancy

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Open Journal of Obstetrics and Gynecology 2020年第10期10卷 1358-1369页

作者： Rui Wang Suping Wu Department of Clinical Nutrition Beijing Anzhen Hospital The Capital Medical University Beijing China

Background: With the rising prevalence in recent years, gestational diabetes mellitus has become one of the leading causes of maternal and child mortality and morbidity worldwide and has raised health concern. It is seriously detrimental to both the women and fetuses. However, there are limited evidences of two types of gestational diabetes mellitus on clinical characteristics and outcomes. Therefore, this study was aimed to explore the clinical characteristics and outcomes of patients with overt diabetes mellitus (ODM) and gestational diabetes mellitus (GDM) at the late pregnancy. Methods: From January 2015 to August 2016, totally 63 gestational diabetes mellitus from the Department of Clinical Nutrition in Beijing Anzhen Hospital were enrolled in the study. Patients were classified into two groups. 31 patients with gestational overt diabetes mellitus were grouped into ODM group and 32 patients with gestational diabetes mellitus were grouped into GDM group. Clinical characteristics and outcomes were compared between ODM and GDM. We collected records of the age, gestational week, family history, past history, pregnancy complications, insulin use, blood pressure, clinical nutrition indexes, blood pressure. Glycosylated hemoglobin (HbA1c), fasting blood glucose (FBG), total protein (TP), albumin (ALB), prealbumin (PALB), hemoglobin (HGB), urea nitrogen (BUN), serum creatinine

关键词： late pregnancy Gestational Diabetes Mellitus Overt Diabetes Mellitus Clinical Characteristics Outcomes

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Clinical Study on the Relationship between the HCG Levels during the late pregnancy and the Delivery Mechanism

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International Journal of Technology Management 2014年第3期 44-46页

作者： Xiaoli DU Jinrong GAO Aijun QI Dongming ZHANG Fan YANG Huifang ZHU Jianhong GAO Zhen WANG People's Hospital of Langfang City HebeiChina Langfang Health Vocational College Hebei 065000 China

Objective： The relationship between the HCG levels during the late pregnancy and the delivery mechanism was discussed. Method： If the HCG levels during the late pregnancy were related to the delivery mechanism was studied by using the β -HCG changes of 100 women pregnant for 36 weeks, 37 weeks, 38 weeks, 39 weeks, 40 weeks, and 41 weeks, and also the [3 -HCG changes when their uterine orifice was opened for 3cm near the time of labor as the clinical data. All these cases were found to suffer no clinical complications. Result： The difference in HCG changes during the late pregnancy was of no statistical significance （P〉0.05）. Conclusion： The β-HCG levels change during the late pregnancy is not significantly correlated with the labor onset time, and the labor onset time is unpredictable with the monitoring of the HCG levels change during the late pregnancy.

关键词： late pregnancy β-HCG Levels Labor Onset Time

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Effect and Safety of Iron Supplementation on Mild Thalassemia Complicated by Iron Deficiency in late pregnancy

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Journal of Clinical and Nursing Research 2021年第6期5卷 15-18页

作者： Yanchuan Li Yanfeng Liu Xue Li Limin Hou Shaanxi Provincial People’s Hospital Xi’an 710068Shaanxi ProvinceChina The Second Affiliated Hospital of Xi’an Medical College Xi’an 710038Shaanxi ProvinceChina

Aim:To study the clinical effect and safety of iron supplementation in the treatment of mild thalassemia complicated by iron deficiency in late ***:376 patients with mild thalassemia complicated by iron deficiency in late pregnancy treated in our hospital from July 2019 to June 2021 were selected and recruited in the research group,and 200 normal pregnant women treated in the same period were selected and recruited in the control ***(Hb),reticulocyte blood,red blood protein(RET he)level,ferritin(SF)level,soluble transferrin receptor(sTfR)level,adverse maternal and infant outcomes,*** ***:There was no significant difference in the levels of SF,Hb,RET he and sTfR between the two groups before *** treatment,the levels of SF,Hb,RET he and sTfR in the research group were significantly improved,which was statistically significant compared with the control *** frequencies of intrapartum hemorrhage,premature delivery,stillbirth,hemorrhagic shock,and neonatal asphyxia in the research group were 289±47.88,36(9.57%),0(0.00%),25(6.65%),and 6(1.26%),*** frequencies of intrapartum hemorrhage,premature delivery,stillbirth,hemorrhagic shock,and neonatal asphyxia in the control group were 284±46.99,7(3.50%),0(0.00%),6(3.00%),and 0(0.00%),*** were significant differences in preterm delivery and hemorrhagic shock,and there was no significant difference in other delivery ***:Under the premise of strictly controlling the iron reserve in pregnant women,continuous medication until the end of delivery may be conducive to the control of maternal thalassemia complicated by iron deficiency and the improvement of pregnancy outcome.

关键词： Iron supplement late pregnancy Mild thalassemia

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Perioperative nursing of multidisciplinary emergency surgery for a late-term pregnancy with acute Stanford type A aortic dissection

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South China Journal of Cardiology 2022年第3期23卷 236-239,243页

作者： SONG Hai-juan XIE Qing CHEN Xiao-xia ZHU Ping GUO Hai-jiang LIU Xiao-min LU Chang-qing ZHUANG Jian SUN Tu-cheng Guangdong Provincial People's Hospital Guangdong Academy of Medical SciencesGuangzhou 510080China

To summarize a case of late pregnancy complicated with acute Stanford type A aortic dissection who underwent multidisciplinary treatment perioperative nursing experience in emergency surgery. The patient was 37weeks of intrauterine pregnancy and suffered from sudden chest pain. The emergency admission was diagnosed with aortic dissection(Stanford A type), and the condition was dangerous and life-threatening. After preoperative multidisciplinary combined systematic comprehensive disease assessment and comprehensive surgical emergency plan was formulated, do a good job of effective psychological counseling and operation cooperation education,nursing cooperation during intraoperative anesthesia and nursing focus of multidisciplinary combined surgical treatment, postoperative prevention of massive bleeding, puerperium infection and a series of effective nursing measures, no perioperative period occurred nursing complications. The newborn survived, the patient recovered and was discharged from the hospital, and returned to the hospital for re-examination with normal indicators and good physical condition.

关键词： late pregnancy Stanford type A aortic dissection Multidisciplinary combination Perioperative care

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Relationship between ultrasound parameters of the umbilical and middle cerebral arteries and intrauterine fetal distress

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World Journal of Clinical Cases 2024年第16期12卷 2745-2750页

作者： Ji Chen Fei-Xue Liu Rui-Xue Tao Department of Obstetrics The Third Affiliated Hospital of Anhui Medical UniversityHefei 230061Anhui ProvinceChina Anhui Medical University First Clinical School of MediumClass 2021Clinical MedicineHefei 230032Anhui ProvinceChina

BACKGROUND By comprehensively analyzing the blood flow parameters of the umbilical and middle cerebral arteries,doctors can more accurately identify fetal intrauterine distress,as well as assess its severity,so that timely interventions can be implemented to safeguard the health and safety of the *** To identify the relationship between ultrasound parameters of the umbilical and middle cerebral arteries and intrauterine *** Clinical data of pregnant women admitted between January 2021 and January 2023 were collected and divided into the observation and control groups(n=50 each),according to the presence or absence of intrauterine *** ultrasound hemodynamic parameters of the uterine artery(UtA),fetal middle cerebral artery(MCA),and umbilical artery(UmA)were compared with neonatal outcomes and occurrence of intrauterine distress in the two *** Comparison of ultrasonic hemodynamic parameters,resistance index(RI),pulsatility index(PI),and systolic maximal blood flow velocity of UmA compared to diastolic blood flow velocity(S/D),revealed higher values of fetal MCA,PI,and S/D of UmA in pregnant women with UtA compared to controls(Plate pregnancy,which suggests that clinical attenti

关键词： late pregnancy Fetal intrauterine distress Ultrasound blood flow parameters Uterine artery Middle cerebral artery Umbilical artery

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