检索结果-南通市图书馆

Erdheim chester-A rare disease with unique endoscopic features

World Journal of Gastroenterology 2014年第25期20卷 8309-8311页

作者： Gil Ben-yaakov Daniela Munteanu Ignacio Sztarkier Alexer Fich Doron Schwartz Institute of Gastroenterology and Hepatology Soroka University Medical Center Faculty of Health Science Ben Gurion University of the NegevBeer sheva 84101Israel Institute of Pathology Soroka University Medical Center Faculty of Health Science Ben Gurion University of the Negev Beer sheva 84101 Israel

Erdheim-Chester disease(ECD) is a rare inflammatory syndrome in which systemic infiltration of non-Langerhans cell histiocytes occurs in different sites. Both the etiology and pathophysiology of ECD are unknown, but CD68 positive CD 1a/S100 negative cells are characteristic. The presentation of ECD differs according to the involved organs. This case report describes a patient with ECD and the gastrointestinal manifestations and unique endoscopic appearance as seen in gastroscopy and colonoscopy with histological proof of histiocyte infiltration of the lamina propria. The clinical and endoscopic findings of this unique case, to our knowledge, were never described before, so were the features of the gastrointestinal involvement in this disease.

关键词： Erdheim chester Histiocytes lamina propria Colon Stomach

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Research on the change and interrelationship between intestine Th17 and Treg in colitis mouse model

Research on the change and interrelationship between intesti...

引用

第九届全国免疫学学术大会

作者： Xuefeng Jiang Fangli Yang Lixuan Sang Junfeng Zhu Yan Li Dan Yue Xiaoyun Sun Jingbo Zhai Xun Sun Changlong Lu Department of Immunology China Medical University

Objective:To investigate the interrelationship between Th17 and Treg in the intestinal mucosa by detecting the numbers of Thl7 and Treg,and the expression of cytokine secretion in different genetic background mice after DSS-induced ***:Colitis was induced by administration of 3.5%dextran sodium sulfate(DSS)in drinking water to mice for *** were isolated from intestinal mucosa lamina propria(LP)and mesenteric lymph nodes(MLN).The numbers of Th17 and Treg were *** expression and production of Th17 and Treg relative cytokines were ***:C57BL/6 mice were susceptible to DSS-induced colitis as compared with Balb/*** mRNA expressions of IL-10 and FoxP3 were markedly lower,but the levels of IFN-γ,IL-6,IL-23 and IL-17a mRNA expressions were significantly higher in LP of C57BL/6 mice than those in Balb/c *** productions of IFN-γ,IL-6,IL-12,IL-23 and IL-17a were increased,but IL-10 was decreased in LP of C57BL/6 mice when compared with those in Balb/c *** numbers of CD4IFN-γcells and CD4IL-17Acells were increased,but the numbers of CD4CD25IL-10and CD4CD25FoxP3were decreased in LP of C57BL/6 mice as compared with those in Balb/c ***:These results suggest that the responses ofThl7and Thl were enhanced mice,but the response of Treg was reduced in the LP of inflammatory intestine and MLN in C57BL/6 mice as compared with Balb/c *** the disbalance of Th17/Treg may be involved in the development of DSS-induced colitis in different genetic background mice.

关键词： ulcerative colitis Th17 Treg lamina propria

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：