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Effects of ovarian response prediction index and follicle-oocyte index on pregnancy outcomes: a retrospective cohort study of 12,218 fresh transfer cycles

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REPRODUCTIVE AND DEVELOPMENTAL MEDICINE 2024年第3期8卷 151-161页

作者： Wang, Mao Tan, Li Ding, Yu-Bin Tang, Xiao-Jun Li, Tian Hu, Xin-Yue Zhong, Hu-Cen Wan, Qi Zhong, Zhao-Hui Chongqing Med Univ Res Ctr Med & Social Dev Innovat Ctr Social Risk Governance Hlth Dept EpidemiolSch Publ Hlth Chongqing 400016 Peoples R China Chongqing Med Univ Sch Publ Hlth Joint Int Res Lab Reprod & Dev Minist Educ China Chongqing 400016 Peoples R China Chengdu Xinan Gynecol Hosp Reprod Ctr Chengdu 610011 Peoples R China Sichuan Univ West China Hosp 2 Dept Gynecol & Obstet Chengdu 610041 Peoples R China Changsha Med Univ Dept Pharmacol Academician Workstat Changsha 410219 Peoples R China Chongqing Med Univ Dept Reprod Med Affiliated Hosp 1 Chongqing 400016 Peoples R China

Objective: To investigate the potential relationships among the ovarian response prediction index (ORPI), follicle-oocyte index (FOI), and clinical pregnancy rate (CPR) in women undergoing their first in vitro fertilization/intracytoplasmic sperm injection-embryo transfer (IVF/ICSI-ET) fresh cycle transfer. Methods In this retrospective cohort study, we included 12,218 women who underwent their first IVF/ICSI-ET cycle between December 2014 and January 2021. The primary and secondary outcomes of our study were CPR and cumulative live birth rate (CLBR), respectively. The data were divided into three groups according to the ORPI and FOI tertiles. Multivariate logistic regression analyses, stratification analyses, interaction, restricted cubic splines, and receiver operating characteristic (ROC) curves were constructed to identify the relationships among ORPI, FOI, and CPR. Results: A statistically significant increase in CPR was detected from the lowest to the highest tertile group (ORPI: 48.12%, 54.07%, and 53.47%, P live birth outcomes in fresh ETs. Clinicians and researchers should avoid using FOI and ORPI to assess pregnancy outcomes after

关键词： In vitro fertilization Controlled ovarian hyperstimulation Ovarian response indexes Ovarian response prediction index Follicle-oocyte index Clinical pregnancy ASSISTED REPRODUCTIVE TECHNOLOGY live birth-rates OUTPUT RATE STIMULATING-HORMONE WOMEN COUNT

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