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Health 2013年第10期5卷 1527-1532页

作者： Masao Yoshida Shinichiro Take Mamoru Ishikawa Kanae Karita Akatsuki Kokaze Matsuko Harada Hideki Ohno Department of Public Health Kyorin University School of Medicine Tokyo Japan

To clarify the interrelationship among blood pressure (BP), intraocular pressure (IOP), and life-style related factors, a cross-sectional study was conducted. This epidemiological study analyzed health examination data obtained between 2001 and 2004 from 1113 Japanese individuals, ranging in age 28 to 79 years, who had not undergone any ocular surgery or medical treatment for hypertension, ocular hypertension, and glaucoma. The association of systolic and diastolic BP (SBP and DBP), and life-style related factors such as body mass index (BMI), drinking, smoking, and exercise habits with IOP were evaluated by multiple regression analyses and analyses of covariance. The results of this study showed that SBP, DBP, and BMI had a significantly positive association with IOP in both sexes. In men, the number of cigarette smoking per day was also positively related to IOP

关键词： Intraocular Pressure Blood Pressure life-style Epidemiology Glaucoma

Effect of a counseling-supported treatment with the Mediterranean diet and physical activity on the severity of the non-alcoholic fatty liver disease

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World Journal of Gastroenterology 2017年第17期23卷 3150-3162页

作者： Chiara Gelli Mirko Tarocchi Ludovico Abenavoli Laura Di Renzo Andrea Galli Antonino De Lorenzo Division of Clinical Nutrition and Nutrigenomics Department of Biomedicine and PreventionUniversity of Rome“Tor Vergata” Department of Experimental and Clinical Biomedical Sciences University of Florence Department of Health Sciences University Magna Graecia

AIM To determine the clinical effectiveness of nutritional counseling on reduction of non-alcoholic fatty liver disease(NAFLD) severity, weight loss, metabolic and anthropometric indexes and liver *** Forty-six adults with NAFLD received a 6-mo clinical and a dietary intervention(based on Mediterranean diet) carried out respectively by a gastroenterologist and a nutritionist with counseling license. The counseling process consisted of monthly meeting(about 45 min each). The effect of the treatment was evaluated monitoring liver enzymes, metabolic parameters, cardiovascular risk indexes, NAFLD severity [assessed by ultrasound(US)] and related indexes. All parameters were assessed at baseline. Biochemistry was also assessed at mid-and end-interventions and US was repeated at *** The percentage of patients with steatosis grade equal or higher than 2 was reduced from 93% to 48% and steatosis regressed in 9 patients(20%). At the end of the treatment the end-point concerning the weight(i.e., a 7% weight reduction or achievement/maintenance of normal weight) was accomplished by 25 out of 46 patients(i.e., 54.3%). As far as the liver enzymes is concerned, all three liver enzymes significantly decrease during the treatment the normalization was particularly evident for the ALT enzyme(altered values reduced from 67% down to 11%). Several parameters, i.e., BMI, waist circumference, waist-to-hip ratio, AST, ALT, GGT, HDL, serum glucose, Tot-Chol/HDL, LDL/HDL, TG/HDL, AIP, HOMA, FLI, Kotronen index, VAI, NAFLD liver fat score and LAP, showed a significant improvement(P lifestyle can be considered a safe therapeutic approach for reducing risk and severity of NAFLD and related disease states. The proposed approach may be proposed as a valid and recommended approach for improving the clinical profile of NAFLD p

关键词： Non-alcoholic fatty liver disease Non-alcoholic steatohepatitis Mediterranean diet Metabolic syndrome Therapeutic approach Counseling Diet life-style

Counting your sperm before they fertilize： are sperm counts really declining？

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Asian Journal of Andrology 2013年第2期15卷 179-183,I0004,I0005页

作者： Alexander W Pastuszak Dolores J Lamb Scott Department of Urology Baylor College of Medicine Houston TX 77030 USA Center for Reproductive Medicine Baylor College of Medicine Houston TX 77030 USA Department of Molecular Cell Biology Baylor College of Medicine Houston TX 77030 USA

Apurported global decline in sperm counts has been a source of controversy since the early 1990s. Numerous studies performed since then, as well as reanalysis of the original data, show either no changes, or even increases, in sperm concentrations over time. In this review, we discuss the 1992 meta-analysis that initiated the continuing debate on whether sperm concentrations are declining, and the com- munity discussion surrounding it over the past two decades. We also highlight studies evaluating sperm concentrations performed since the initial study that produced different results, and conclude that no definitive cause for a decrease in sperm counts has been established, and the effects of geography and environment on sperm counts are unclear.

关键词： YOUNG DANISH MEN SEMEN QUALITY DECREASING QUALITY life-style REGIONAL DIFFERENCES GENERAL-POPULATION MALE-INFERTILITY HEALTHY-MEN FINNISH MEN AREA

Self-assessed health and its aspects in the case of Mongolia

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Health 2012年第7期4卷 415-422页

作者： Amarsanaa Gan-Yadam Ryoji Shinohara Yuka Sugisawa Emiko Tanaka Taeko Watanabe Maki Hirano Etsuko Tomisaki Kentaro Morita Yoko Onda Yuri Kawashima Kentaro Toketake Yukiko Mochizuki Mayumi Nanba Tokie Anme Graduate School of Comprehensive Human Sciences University of Tsukuba Tsukuba Japan

Self health assessment is a simple indicator that is widely used for measuring an individual’s perception of his or her overall health. Many studies have been conducted by way of showing which particular aspects should be included in health self assessment, especially in developed world. In the developing world, however, very few studies have examined self health assessment. The aim of this study was to identify particular aspects and associations in self health assessment and differences between subgroups in Ulaanbaatar, Mongolia. The area sampling approach and Kish tables were used for selecting respondents. Total 500 respondents were surveyed by paper-based questionnaires. Spearman’s analysis and multiple logistic regression analysis were used to show relations between variables. Sociodemographic status, such as age and gender, proved to be important in self health assessment. Other factors affecting self health assessment included the number of family members, daily life and lifestyles, social environment, community motivation, and utilization of health services. Women, the elderly, or people with less-than- normal access to information suffer from poor self-assessed health. People who are socially inactive and who have poor living conditions are less likely to use health care services and are likely to assess their health as “poor.” In order to reduce the poor self-assessed health status it is important to address disparities in socioeconomic factors, such as age, gender, employment, and residential area. In addition, more attention should be paid to community and health services, as well as to health promotion and empowerment activities, including income-generation activities. Further research is also needed, however, for better understanding of about the local people and their health-related issues.

关键词： Self-Assessed Health Socio-Demographic Status Daily life and life-style Community Motivation Social Environment Health Service Utilization and Mongolia

Cigarette smoking and the risk of endometrial cancer:A meta-analysis

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南京医科大学学报(自然科学版) 2008年第7期 939-939页

作者： Zhou,B. Yang,L. Sun,Q.M. Cong,R.H. Gu,H.J. Tang,N.P. Zhu,H.J. Wang,B.Nanjing Med Univ,Dept Pharmacol,Key Lab Reproduct Med,Nanjing 210029,Jiangsu,Peoples R China.Nanjing Med Univ,Affiliated Hosp 1,Dept Gen Surg,Nanjing 210029,Jiangsu,Peoples R China.Nanjing Univ,Sch Med,Affiliated Drum Tower Hosp,Nanjing 210008,Jiangsu,Peoples R China.

OBJECTIVE:Epidemiologic findings are inconsistent concerning the association of endometrial cancer risk with cigarette *** conducted a meta-analysis of epidemiologic studies to examine this ***:A systematic literature search up to June of 2007 was performed in MEDLINE and ***-specific risk estimates were pooled using a random-effects ***:Ten prospective and 24 case-control studies were included in the analysis of the effect of ever *** smoking was statistically significantly associated with a reduced risk of endometrial cancer among prospective studies(relative risk 0.81;95% confidence interval[CI],0.74-0.88) and case-control studies(odds ratio 0.72;95% CI,0.66-0.79).The inverse association was significant among current and former *** prospective and 6 case-control studies were included in the quantitative *** noted that an increase in smoking of 20 cigarettes per day was statistically significantly associated with 16% and 27% reduced risks of endometrial cancer in prospective and case-control studies,*** also found that cigarette smoking was significantly associated with a decreased risk of endometrial cancer among postmenopausal women(relative risk 0.71;95% CI,0.65-0.78) but not among premenopausal *** addition,the risk reduction seemed to be stronger among hormone replacement therapy users than ***:Cigarette smoking was found to be significantly associated with a reduced risk of endometrial cancer,especially among postmenopausal women.(C) 2008 Elsevier *** rights reserved.

关键词： cigarette smoking endometrial cancer meta-analysis risk hormone-replacement therapy dose-response data alcohol-consumption postmenopausal women trend estimation estrogen use life-style aarp diet follow-up cohort