检索结果-南通市图书馆

Gastric cancer incidence based on endoscopic kyoto classification of gastritis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2023年第31期29卷 4763-4773页

作者： Osamu Toyoshima Toshihiro Nishizawa Shuntaro Yoshida Tatsuya Matsuno Gota Fujisawa Akira Toyoshima Hirotoshi Ebinuma Mitsuhiro Fujishiro Yutaka Saito Hidekazu Suzuki Department of Gastroenterology Toyoshima Endoscopy ClinicTokyo 157-0066Japan Department of Gastroenterology and Hepatology International University of Health and WelfareNarita HospitalNarita 286-8520Japan Department of Colorectal Surgery Japanese Red Cross Medical CenterTokyo 150-8935Japan Department of Gastroenterology Graduate School of MedicineThe University of TokyoTokyo 113-8655Japan Division of Endoscopy National Cancer Center HospitalTokyo 104-0045Japan Division of Gastroenterology and Hepatology Department of Internal MedicineTokai University School of MedicineIsehara 259-1193Japan

BACKGROUND Gastric cancer(GC)incidence based on the endoscopic kyoto classification of gastritis has not been systematically investigated using time-to-event *** To examine GC incidence in an endoscopic surveillance *** This study was retrospectively conducted at the Toyoshima Endoscopy *** who underwent two or more esophagogastroduodenoscopies were *** incidence was based on kyoto classification scores,such as atrophy,intestinal metaplasia(IM),enlarged folds(EFs),nodularity,diffuse redness(DR),and total kyoto *** ratios(HRs)adjusted for age and sex were calculated using a Cox hazard *** A total of 6718 patients were enrolled(median age 54.0 years;men 44.2%).During the follow-up period(max 5.02 years;median 2.56 years),GC developed in 34 *** average frequency of GCs per year was 0.19%.kyoto atrophy scores 1[HR with score 0 as reference:3.66,95%confidence interval(CI):1.06 to 12.61],2(11.60,3.82-35.27),IM score 2(9.92,4.37-22.54),EF score 1(4.03,1.63-9.96),DR scores 1(6.22,2.65-14.56),and 2(10.01,3.73-26.86)were associated with GC incidence,whereas nodularity scores were *** total kyoto scores of 4(HR with total kyoto scores 0-1 as reference:6.23,95%CI:1.93 to 20.13,P=0.002)and 5-8(16.45,6.29-43.03,Pkyoto scores 2-3 were *** HR of the total kyoto score for developing GC per 1 rank was 1.75(95%CI:1.46 to 2.09,Pkyoto score(≥4)was associated with GC *** endoscopy-based diagnosis of gastritis can stratify GC risk.

关键词： Gastric cancer Gastritis Endoscopy Atrophy Intestinal metaplasia kyoto classification

Endoscopy-based kyoto classification score of gastritis related to pathological topography of neutrophil activity

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2020年第34期26卷 5146-5155页

作者： Osamu Toyoshima Toshihiro Nishizawa Shuntaro Yoshida Yoshiki Sakaguchi Yousuke Nakai Hidenobu Watanabe Hidekazu Suzuki Chizu Tanikawa Koichi Matsuda Kazuhiko Koike Department of Gastroenterology Toyoshima Endoscopy ClinicTokyo 157-0066Japan Department of Gastroenterology Graduate School of MedicineThe University of TokyoTokyo 113-8655Japan Department of Gastroenterology and Hepatology International University of Health and WelfareNarita HospitalChiba 286-8520Japan Department of Endoscopy and Endoscopic Surgery Graduate School of MedicineThe University of TokyoTokyo 113-8655Japan Department of Pathology Pathology and Cytology Laboratory JapanTokyo 166-0003Japan Department of Gastroenterology and Hepatology Tokai University School of MedicineKanagawa 259-1193Japan Laboratory of Molecular Medicine Human Genome CenterInstitute of Medical ScienceThe University of TokyoTokyo 108-8639Japan Department of Computational Biology and Medical Sciences Laboratory of Clinical Genome SequencingGraduate School of Frontier SciencesThe University of TokyoTokyo 108-8639Japan

BACKGROUND Endoscopy-based kyoto classification for gastritis and pathological topographic distribution of neutrophil infiltration are correlated with gastric cancer *** To investigate the association between kyoto classification and the topographic distribution of neutrophil *** kyoto classification score,ranging from 0 to 8,consisted of atrophy,intestinal metaplasia,enlarged folds,nodularity,and diffuse *** activity was scored according to the updated Sydney System using biopsy samples obtained from the greater curvature of the corpus and the *** participants were divided into four categories,inactive stomach,antrumpredominant gastritis,pangastritis,and corpus-predominant gastritis,based on the topographic distribution of neutrophil *** of sex,age,body mass index,drinking habit,smoking habit,family history of gastric cancer,serum Helicobacter pylori(***)antibody,and kyoto score on topography of neutrophil infiltration were *** A total of 327 patients(comprising 50.7%women,with an average age of 50.2 years)were enrolled in this *** infection rate was 82.9%with a mean kyoto score of *** kyoto score was associated with the topographic distribution of neutrophil *** scores were significantly higher in the order of inactive stomach,antrum-predominant gastritis,pangastritis,and corpuspredominant gastritis(3.05,4.57,5.21,and 5.96,respectively).Each individual score of endoscopic findings(i.e.,atrophy,intestinal metaplasia,enlarged folds,nodularity,and diffuse redness)was correlated with the topographic distribution of neutrophil *** multivariate analysis,the kyoto score,age,and serum *** antibody were independently associated with the topographic distribution of neutrophil *** The kyoto classification score was associated with the topographic distribution of neutrophil activity.

关键词： kyoto classification Helicobacter pylori Neutrophil activity Updated Sydney System Gastritis Gastric cancer Endoscopy Pathology

Endoscopic kyoto classification of Helicobacter pylori infection and gastric cancer risk diagnosis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2020年第5期26卷 466-477页

作者： Osamu Toyoshima Toshihiro Nishizawa Kazuhiko Koike Department of Gastroenterology Toyoshima Endoscopy ClinicTokyo 157-0066Japan Department of Gastroenterology Graduate School of MedicineThe University of TokyoTokyo 113-8655Japan Department of Gastroenterology and Hepatology International University of Health and WelfareMita HospitalTokyo 108-8329Japan

Recent advances in endoscopic technology allow detailed observation of the gastric ***,endoscopy is used in the diagnosis of gastritis to determine the presence/absence of Helicobacter pylori(***)infection and evaluate gastric cancer *** 2013,the Japan Gastroenterological Endoscopy Society advocated the kyoto classification,a new grading system for endoscopic *** kyoto classification organized endoscopic findings related to *** *** kyoto classification score is the sum of scores for five endoscopic findings(atrophy,intestinal metaplasia,enlarged folds,nodularity,and diffuse redness with or without regular arrangement of collecting venules)and ranges from 0 to ***,intestinal metaplasia,enlarged folds,and nodularity contribute to gastric cancer *** redness and regular arrangement of collecting venules are related to *** infection *** subjects without a history of *** eradication,the infection rates in those with kyoto scores of 0,1,and≥2 were 1.5%,45%,and 82%,respectively.A kyoto classification score of 0 indicates no *** infection.A kyoto classification score of 2 or more indicates *** *** classification scores of patients with and without gastric cancer were 4.8 and 3.8,respectively.A kyoto classification score of 4 or more might indicate gastric cancer risk.

关键词： Gastric cancer Helicobacter pylori Endoscopy kyoto classification Atrophy Intestinal metaplasia Enlarged fold Nodularity Diffuse redness Regular arrangement of collecting venules

kyoto classification in patients who developed multiple gastric carcinomas after Helicobacter pylori eradication

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Endoscopy 2020年第9期12卷 276-284页

作者： Kosuke Sakitani Toshihiro Nishizawa Akira Toyoshima Shuntaro Yoshida Tatsuya Matsuno Tomoharu Yamada Masatoshi Irokawa Yoshiyuki Takahashi Yousuke Nakai Osamu Toyoshima Kazuhiko Koike Department of Gastroenterology Toyoshima Endoscopy ClinicTokyo 157-0066Japan Department of Gastroenterology Sakitani Endoscopy ClinicChiba 275-0026Japan Department of Gastroenterology International University of Health and WelfareNarita HospitalChiba286-8520Japan Department of Colorectal Surgery Japanese Red Cross Medical CenterTokyo 150-8935Japan Department of Gastroenterology Graduate School of Medicinethe University of TokyoTokyo 113-8655Japan

BACKGROUND Endoscopic kyoto classification predicts gastric cancer risk;however,the score in the patients with primary gastric cancer after Helicobacter pylori(***)eradication therapy is *** To elucidate the kyoto classification score in patients with both single gastric cancer and multiple gastric cancers developed after *** *** The endoscopist recorded the kyoto classification at the endoscope and the kyoto classification score at the time of the first diagnosis of gastric cancer after *** *** score was compared between single gastric cancer group and multiple gastric cancers *** The kyoto score at the time of diagnosis of 45 cases of gastric cancer after *** eradication was 4.0 points in *** score was 3.8 points in the single gastric cancer group,and 5.1 points in the multiple gastric cancers *** multiple group had a significantly higher score than the single group(P=0.016).In the multiple gastric cancers group,all the patients(7/7)had 5 or higher kyoto score,while in single gastric cancer group,the proportion of patients with a score of 5 or higher was less than half,or 44.7%(17/38).CONCLUSION Patients diagnosed with gastric cancer after *** eradication tended to have advanced *** particular,in cases of multiple gastric cancers developed after *** eradication,the endoscopic kyoto classification score tended to be 5 or higher in patients with an open type atrophic gastritis and the intestinal metaplasia extended to the corpus.

关键词： kyoto classification Gastric cancer Helicobacter pylori Eradication therapy Metachronous Intestinal metaplasia

Comparison of endoscopic gastritis based on kyoto classification between diffuse and intestinal gastric cancer

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Endoscopy 2021年第5期13卷 125-136页

作者： Osamu Toyoshima Toshihiro Nishizawa Shuntaro Yoshida Tomonori Aoki Fumiko Nagura Kosuke Sakitani Yosuke Tsuji Hayato Nakagawa Hidekazu Suzuki Kazuhiko Koike Department of Gastroenterology Toyoshima Endoscopy ClinicTokyo 157-0066Japan Department of Gastroenterology and Hepatology International University of Health and WelfareNarita HospitalNarita 286-8520Japan Department of Gastroenterology Graduate School of MedicineThe University of TokyoTokyo 113-8655Japan Internal Medicine Chitosefunabashi Ekimae ClinicTokyo 157-0054Japan Department of Gastroenterology Sakiatani Endoscopy ClinicNarashino 275-0026Japan Department of Gastroenterology and Hepatology Tokai University School of MedicineIsehara 259-1193Japan

BACKGROUND Gastric cancers can be categorized into diffuse-and intestinal-type cancers based on the Lauren histopathological *** two subtypes show distinct differences in metastasis frequency,treatment application,and ***,accurately assessing the Lauren classification before treatment is ***,studies on the gastritis endoscopy-based kyoto classification have recently shown that endoscopic diagnosis has *** To investigate patient characteristics including endoscopic gastritis associated with diffuse-and intestinal-type gastric cancers in Helicobacter pylori(***)-infected *** Patients who underwent esophagogastroduodenoscopy at the Toyoshima Endoscopy Clinic were *** kyoto classification included atrophy,intestinal metaplasia,enlarged folds,nodularity,and diffuse *** effects of age,sex,and kyoto classification score on gastric cancer according to the Lauren classification were *** developed the Lauren predictive background score based on the coefficients of a logistic regression model using variables independently associated with the Lauren *** under the receiver operative characteristic curve and diagnostic accuracy of this score were *** A total of 499 ***-infected patients(49.6%males;average age:54.9 years)were enrolled;132 patients with gastric cancer(39 diffuse-and 93 intestinal-type cancers)and 367 cancer-free controls were *** cancer was independently associated with age≥65 years,high atrophy score,high intestinal metaplasia score,and low nodularity score when compared to the *** independently associated with intestinal-type cancer were age≥65 years(coefficient:1.98),male sex(coefficient:1.02),high intestinal metaplasia score(coefficient:0.68),and low enlarged folds score(coefficient:-1.31)when compared to diffuse-type *** Lauren predictive background score was defined as the sum of+2(age≥65 years),+1(

关键词： Gastric cancer Lauren classification Endoscopy Pathology Gastritis kyoto classification

Non-improvement of atrophic gastritis in cases of gastric cancer after successful Helicobacter pylori eradication therapy

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2024年第14期12卷 2342-2349页

作者： Yuto Suzuki Yasumi Katayama Yo Fujimoto Ikuhiro Kobori Masaya Tamano Department of Gastroenterology Dokkyo medical University Saitama Medical CenterKoshigayaSaitama 343-8555Japan Endoscopy Center Dokkyo Medical University Saitama Medical CenterKoshigayaSaitama 343-8555Japan

BACKGROUND Helicobacter pylori(***)infection is closely related to the development of gastric cancer(GC).However,GC can develop even after *** ***,it would be extremely useful if GC could be predicted after *** kyoto classification score for gastritis(GA)is closely related to cancer ***,how the score for GC changes after eradication before onset is not well *** To investigate the characteristics of the progression of kyoto classification scores for GC after *** *** Eradication of *** was confirmed in all patients using either the urea breath test or the stool antigen *** kyoto classification score of GC patients was evaluated by endoscopy at the time of event onset and three years *** ad-dition,the modified atrophy score was evaluated and compared between the GC group and the control GA *** In total,30 cases of early GC and 30 cases of chronic GA were *** pathology of the cancer cases was differentiated adenocarcinoma,except for one case of undifferentiated *** total score of the kyoto classifi-cation was significantly higher in the GC group both at the time of cancer onset and three years earlier(4.97 vs 3.73,P=0.0034;4.2 vs 3.1,P=0.0035,respectively).The modified atrophy score was significantly higher in the GC group both at the time of cancer onset and three years earlier and was significantly improved only in the GA group(5.3 vs 5.3,P=0.5;3.73 vs 3.1,P=0.0475,respectively).CONCLUSION The course of the modified atrophy score is useful for predicting the onset of GC after *** with severe atrophy after *** eradication require careful monitoring.

关键词： Helicobacter pylori kyoto classification Gastritis Eradication therapy Gastric cancer

Enlarged folds on endoscopic gastritis as a predictor for submucosal invasion of gastric cancers

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Endoscopy 2021年第9期13卷 426-436页

作者： Osamu Toyoshima Shuntaro Yoshida Toshihiro Nishizawa Akira Toyoshima Kosuke Sakitani Tatsuya Matsuno Tomoharu Yamada Takashi Matsuo Hayato Nakagawa Kazuhiko Koike Department of Gastroenterology Toyoshima Endoscopy ClinicSetagayaku 157-0066TokyoJapan Department of Gastroenterology and Hepatology International University of Health and WelfareNarita HospitalNarita 286-8520ChibaJapan Department of Colorectal Surgery Japanese Red Cross Medical CenterShibuya-ku 150-8935TokyoJapan Department of Gastroenterology Sakitani Endoscopy ClinicNarashino 275-0026ChibaJapan Department of Gastroenterology Graduate School of MedicineThe University of TokyoBunkyo-ku 113-8655TokyoJapan Department of Internal Medicine Sakura Internal Medicine ClinicSetagayaku 157-0071TokyoJapan

BACKGROUND Accurate diagnosis of the depth of gastric cancer invasion is crucial in clinical *** diagnosis of gastric cancer depth is often made using endoscopic characteristics of the tumor and its margins;however,evaluating invasion depth based on endoscopic background gastritis remains *** To investigate predicting submucosal invasion using the endoscopy-based kyoto classification of *** Patients with gastric cancer detected on esophagogastroduodenoscopy at Toyoshima Endoscopy Clinic were *** analyzed the effects of patient and tumor characteristics,including age,sex,body mass index,surveillance endoscopy within 2 years,current Helicobacter pylori infection,the kyoto classification,and Lauren’s tumor type,on submucosal tumor invasion and curative endoscopic *** kyoto classification included atrophy,intestinal metaplasia,enlarged folds,nodularity,and diffuse *** was characterized by non-reddish and low *** metaplasia was detected as patchy whitish or grayish-white flat elevations,forming an irregular uneven *** enlarged fold referred to a fold width≥5 mm in the greater curvature of the *** was characterized by goosebump-like multiple nodules in the *** redness was characterized by uniform reddish nonatrophic mucosa in the greater curvature of the *** A total of 266 gastric cancer patients(mean age,66.7 years;male sex,58.6%;mean body mass index,22.8 kg/m2)were ***-three patients underwent esophagogastroduodenoscopy for surveillance within 2 years,and 140 had current Helicobacter pylori *** mean kyoto score was ***-eight cancers were diffuse-type,and 87 cancers had invaded the *** analysis revealed that low body mass index(odds ratio 0.88,P=0.02),no surveillance esophagogastroduodenoscopy within 2 years(odds ratio 0.15,P<0.001),endoscopic enlarged folds of gastritis(odds ratio 3.39,P=0.001),and Lauren’s

关键词： Gastric cancer Gastritis Enlarged fold Endoscopy kyoto classification