检索结果-南通市图书馆

Factors Associated with Development of Vitiligo in Patients with Halo Nevus

Chinese Medical Journal 2017年第22期130卷 2703-2708页

作者： Hui Zhou Liang-Cai Wu Mu-Kai Chen Qi-Man Liao Ren-Xiang Mao Jian-De Han Department of Dermatology The First Affiliated Hospital Sun Yat-sen University Guangzhou Guangdong 510080 China Department of Dermatology The Sixth Affiliated Hospital Sun Yat-sen University Guangzhou Guangdong 510650 China

Background： Halo nevus （HN） has been shown to be associated with vitiligo, but no standard signs are currently available to identify HN patients at risk of vitiligo, and the relevant data obtained in previous studies are somewhat conflicting. This study aimed to identify factors affecting the presence of vitiligo in HN patients. Methods： We performed a retrospective study on consecutive patients with HN at the First Affiliated Hospital of Sun Yat-sen University between January 2011 and December 2016. Detailed demographic and clinical data were collected to identify the factors associated with the presence ofvitiligo in this cohort of patients using uni- and multi-variate logistic regression analyses. Results： A total of 212 HN patients were included, 101 of whom had vitiligo-associated HN （HNV）. Univariate analysis indicated that a personal history of thyroid diseases was positively associated with HNV （odds ratio [OR] 10.761, P = 0,025）, while the onset age of HN was negatively associated with HNV （OR =0.537, P= 0.026）. Multivariate analysis demonstrated that the koebner phenomenon （KP： OR = 10.632, P 〈 0.0001）, multiple HN （OR = 3.918, P 〈 0.0001）, and a familial history of vitiligo （OR = 3.222, P= 0.014） were independent factors associated with HNV. Conclusions： HN without vitiligo has clinical features distinct from HN associated with vitiligo. HN patients with KR multiple lesions, or familial history ofvitiligo are more likely to develop vitiligo and theretbre should be monitored for clinical signs of such accompanied conditions.

关键词： koebner phenomenon Nevus Halo Risk Factors Vitiligo

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：