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kimura disease: A Rare Case of Parotid Localization and Review of the Literature (Case Report)

International Journal of Otolaryngology and Head & Neck Surgery 2023年第4期12卷 287-292页

作者： Drissia Benfadil Lachakar Azzedine Fahd El Idrissi El Ayoubi Department of Otorhinolaryngology and Head & Neck Surgery Oto-Neuro-Ophthalmology Research Laboratory (LRONO) Medicine Faculty University Mohammed I Oujda Morocco

kimura’s disease is a rare chronic affection of unknown etiology, endemic in the far east with a net male predominance. We present the case of a 37-year-old female patient who developed a tumor process in the left parotid region over a period of 3 years. A total left parotidectomy was performed with simple postoperative course. The anatomopathological study of the surgical specimen was in favor of kimura’s disease. Through this case and a review of the literature, we present the main clinical, anatomopathological, therapeutic and evolutionary characteristics of this rare disease.

关键词： kimura disease Parotid Rare

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kimura disease:review of the literature

Kimura disease:review of the literature

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作者： Q.-F.Sun,~1 D.-Z.Xu,~2 S.-H.Pan,~3 J.-G.Ding,~1 Z.-Q.Xue,~4 C.-S.Miao,~4 G.-J.Cao~5 and D.-J.Jin~1 Departments of lInfectious diseases,3Pathology,4Nephrology and 5Surgery,The Third Affiliated Hospital to Wenzhou Medical College, Wenzhou,Zhejiang and 2Beijing Di-tan Hospital,Beijing,China

kimura disease(KD) is a rare,chronic inflammatory disease of unknown cause and is characterized by painless *** and lymphadenopathy commonly affecting the head and neck *** therapeutics has been used to treat KD,but is not satisfactory because of frequent *** has been reported previously to be useful for treatment of hypereosinophilic syndrome and may work by selectively blocking protein -tyrosine kinases,such as plateletderived growth factor receptor, and *** out immunohistochemical examination of platelet-derived growth factor receptor and cit in tissues from patients with KD. The results were positive and suggested that Imatinib might be an effective drug for the treatment of the *** have also briefly reviewed the epidemiology,aetiology,clinical manifestations,laboratory and pathological examinations,differential diagnoses,treatment and prognosis of KD in this manuscript.

关键词： kimura disease eosinophilia immunohistochemistry protein-tyrosine kinase Imatinib.

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