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Partial response to Chinese patent medicine kangliu pill for adult glioblastoma: A case report and review of the literature

引用

World Journal of Clinical Cases 2021年第12期9卷 2845-2853页

作者： Ge Sun Wei Zhuang Qing-Tang Lin Lei-Ming Wang Yu-Hang Zhen Sheng-Yan Xi Xiao-Lan Lin Department of Pharmacy Xuanwu Hospital of Capital Medical UniversityBeijing 100053China Department of Neurosurgery Xuanwu Hospital of Capital Medical UniversityBeijing 100053China Department of Traditional Chinese Medicine School of Medicine and Cancer Research CenterXiamen UniversityXiamen 361102Fujian ProvinceChina

BACKGROUND Glioblastoma is the most common type of brain tumor and is invariably fatal,with a mean survival time of 8-15 mo for recently diagnosed tumors,and a 5-year survival rate of only 7.2%.The standard treatment for newly diagnosed glioblastoma includes surgery followed by concurrent chemoradiotherapy and further adjuvant ***,the prognosis remains poor and longterm survival is *** report aimed to demonstrate a new therapeutic strategy for the treatment of *** SUMMARY A patient was referred to the Department of Neurosurgery with an intracranial space-occupying lesion with a maximum diameter of approximately 5 *** tumor was compressing functional areas,and the patient accordingly underwent partial resection and concurrent *** imaging and pathological findings were consistent with a diagnosis of glioblastoma with oligodendroglioma differentiation(World Health Organization IV).The patient was finally diagnosed with ***,the patient discontinued treatment due to intolerable side effects,and was prescribed kangliu pill(KLP)7.5 g three times/d,which he has continued to *** shrinkage of the tumor(maximum diameter reduced from about 3.5 to about 2 cm)was found after 3 mo of KLP therapy,and the tumor was further reduced to about 1 cm after 3 *** patient’s symptoms of headache,limb weakness,and left hemiplegia were relieved,with no side *** KLP has been a successful intervention for glioblastoma, and the current caseindicates that traditional Chinese medicine may offer effective alternativetherapies for glioblastoma.

关键词： Glioblastoma kangliu pill Traditional Chinese medicine Therapeutic effect Adjunct therapy Chinese patent medicine Case report

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